Penicolinate B is a picolinic acid derivative with significant biological activity. It demonstrates potent antimalarial properties (IC50: 1.40 μg/mL), along with effective antitubercular activity (MIC: 25.0 μg/mL) and inhibition of Bacillus cereus (IC50: 25.0 μg/mL). Additionally, it shows antifungal activity against Candida albicans (IC50: 1.45 μg/mL) and exhibits cytotoxic effects on cancer cell lines, including MCF-7, KB, and NCI-H187. This compound is useful in research focused on malaria, tuberculosis, bacterial and fungal infections, as well as cancer.
Penicolinate B is a picolinic acid derivative with significant biological activity. It demonstrates potent antimalarial properties (IC50: 1.40 μg/mL), along with effective antitubercular activity (MIC: 25.0 μg/mL) and inhibition of Bacillus cereus (IC50: 25.0 μg/mL). Additionally, it shows antifungal activity against Candida albicans (IC50: 1.45 μg/mL) and exhibits cytotoxic effects on cancer cell lines, including MCF-7, KB, and NCI-H187. This compound is useful in research focused on malaria, tuberculosis, bacterial and fungal infections, as well as cancer.
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