Catalog No.
Product Name
Application
Product Information
Citations
-
Antibiotic
Aldgamycin E is a neutral macrolide antibiotic derived from the culture filtrates of Streptomyces lavendulae. It exhibits significant antibacterial activity against various Gram-positive bacteria. This compound is utilized in microbiological studies for elucidating antibiotic mechanisms and assessing microbial resistance. -
Antibiotic
Malonomicin is an antibiotic that primarily targets bacterial and protozoan pathogens. It exhibits notable anti-protozoa and anti-trypanosome activities, demonstrating efficacy in both in vitro and in vivo models against Trypanosoma species. This compound is valuable for research in infectious disease mechanisms and the development of novel therapeutics for protozoan infections. -
Antibiotic
Epopromycin A is a potent antibiotic that disrupts cell wall synthesis in lettuce protoplasts, demonstrating significant herbicidal activity. Additionally, it exhibits notable cytotoxic effects against B16 melanoma cells, with an IC50 value of 0.003 µg/mL. This compound may be utilized in research applications focused on plant pathology and cancer therapeutics. -
Broad-Spectrum Antibiotic
(4S,5S,6S,12aS)-Oxytetracycline is a broad-spectrum antibiotic that targets bacterial protein synthesis by inhibiting ribosomal translation. This compound is a significant member of the bacterial aromatic polyketone family, exhibiting various biological activities. It is commonly utilized in research to study antibiotic mechanisms and bacterial resistance, as well as to explore the role of protein synthesis in microbial physiology. -
Antibiotic
Azlocillin is a semisynthetic penicillin antibiotic that acts primarily by inhibiting bacterial cell wall synthesis. This compound exhibits broad-spectrum antibacterial activity, making it effective against a variety of gram-positive and gram-negative bacteria. Notably, Azlocillin demonstrates activity against drug-tolerant Borrelia burgdorferi sensu stricto JLB31, thus serving as a valuable tool in research focused on antibiotic resistance and Lyme disease. -
Antibiotic
Garenoxacin mesylate is an orally active quinolone antibiotic that targets DNA gyrase and topoisomerase IV. It exhibits a broad spectrum of antibacterial activity against both gram-positive and gram-negative bacteria, as well as anaerobic organisms. This compound is utilized in research applications focusing on antibacterial efficacy and resistance mechanisms. -
Antibiotic
11-Demethyltomaymycin is an antibiotic that exhibits potent antiviral activity against Escherichia coli T1 and T3 phages, as well as antibacterial effects against Gram-positive bacterial strains. Additionally, this compound demonstrates cytotoxicity against leukemia L1210 cells, making it a valuable tool in cancer research and microbiological studies. Its multifaceted biological activity supports its potential applications in both therapeutic development and mechanistic studies of bacterial and viral infections. -
Antibiotic
Arizonin B1 is an antibiotic compound primarily targeting Gram-positive bacteria. Derived from microbial sources, it exhibits significant antibacterial activity, making it a valuable tool for research in microbial resistance and antibiotic efficacy. Its application extends to studies focusing on the mechanisms of action against pathogenic strains, contributing to the development of new therapeutic strategies. -
Antibacterial Agent
Mupirocin calcium is an orally active antibacterial agent derived from Pseudomonas fluorescens. It primarily functions by reversibly inhibiting isoleucyl-transfer RNA, which disrupts bacterial protein and RNA synthesis, leading to effective antimicrobial activity. This compound is utilized in research applications aimed at studying bacterial resistance mechanisms and the development of new antibacterial therapies. -
Antibiotic
Alahopcin is a dipeptide antibiotic that exerts its activity by inhibiting bacterial protein synthesis. It demonstrates a broad spectrum of antibacterial efficacy, making it useful for research applications in microbiology and infectious disease studies. Its unique mechanism of action allows for exploration of antibiotic resistance and the development of new therapeutic strategies. -
Antibiotic
Phospholine is an antibiotic that targets bacterial growth and proliferation. It demonstrates potent cytotoxic activity, with IC50 values of 3.37 μg/mL for Ll 210 cells, 2.20 μg/mL for P388 cells, and 1.99 μg/mL for EL-4 cells. This compound is applicable in research settings focused on antimicrobial resistance and the development of novel therapeutic strategies. -
Antibiotic
YM-17K is a macrolide antibiotic that targets bacterial cell function. It demonstrates broad-spectrum antimicrobial activity against Gram-positive and Gram-negative bacteria as well as anaerobic bacteria. With stable activity in serum and reduced sensitivity to pH fluctuations, YM-17K is valuable for research applications in microbiology and antibiotic resistance studies. -
Bacterial Inhibitor
MGB-BP-3 is a bacterial inhibitor that targets multi-resistant Gram-positive pathogens. This antibiotic exhibits potent activity across a variety of clinically relevant bacterial strains, making it a valuable tool for studies focused on combating antibiotic resistance. Its broad-spectrum efficacy supports research applications in antibiotic development and microbiology. -
Antibiotic
Rubiginone D2 is an antibiotic known for its antimicrobial activity against Bacillus subtilis, Staphylococcus aureus, and Escherichia coli. In addition to its antibacterial properties, Rubiginone D2 demonstrates significant antitumor efficacy, inhibiting the proliferation of various cancer cell lines, including HM02, Kato III, HepG2, and MCF7, with GI50 values of 0.1, 0.7, less than 0.1, and 7.5 μM, respectively. This compound is valuable for research on antibiotic resistance and cancer therapeutics. -
Antibiotic
Amicetin is a potent antibiotic that primarily targets bacterial protein synthesis. Demonstrating significant activity against gram-positive bacteria, Amicetin effectively disrupts cellular processes essential for bacterial growth and replication. This compound is valuable for research applications focused on elucidating antibiotic mechanisms and developing new therapeutic strategies against resistant bacterial strains. -
Antibiotic
Martinomycin is an antibiotic that targets bacterial infections by inhibiting the growth of Staphylococcus spp., Streptococcus spp., and Enterococcus spp. It demonstrates a minimum inhibitory concentration (MIC) range of 0.06 to 0.5 μg/mL, indicating potent antibacterial activity. This compound is valuable in microbiological studies and research focused on antibiotic resistance mechanisms. -
Macrolide Antibiotic
PF-945863 is an orally active macrolide antibiotic that targets bacterial ribosomes, thereby inhibiting protein synthesis. This compound demonstrates significant efficacy against multidrug-resistant respiratory tract bacterial strains, making it a valuable tool for research in combating antibiotic resistance. Its application extends to studies aimed at understanding bacterial resistance mechanisms and developing new therapeutic strategies. -
Antibiotic
Diastovaricin I, a derivative of naphthomycin, functions primarily as an antibiotic. It is notable for its ability to induce differentiation in mouse Friend cells, making it a valuable tool for studies in cell biology and differentiation processes. Its unique mechanism and biological activity position it as a potential reagent for research involving cellular development and related applications. -
Antibiotic
Cefalonium dihydrate is a cephalosporin antibiotic with a primary action against Staphylococcus aureus. This compound exhibits both antibacterial and anti-inflammatory properties, making it a valuable reagent in the study of bacterial infections and inflammation-related research. Cefalonium dihydrate is suitable for applications in microbiology and pharmacology, providing insights into antibiotic efficacy and therapeutic development. -
β-lactam Antibiotic
Mezlocillin is a β-lactam antibiotic with a semisynthetic structure and extended-spectrum activity. It demonstrates efficacy against a wide range of both gram-negative and gram-positive bacteria. Mezlocillin is suitable for research applications focused on bacterial infections and the investigation of antibiotic resistance mechanisms. -
oxazolidinone antibiotic
Posizolid (AZD2563) is an oxazolidinone antibiotic designed for the treatment of bacterial infections. This compound exhibits potent anti-mycobacterial activity, making it a valuable tool in research focused on mycobacterial diseases, including tuberculosis. Its mechanism of action involves inhibition of protein synthesis, targeting the bacterial ribosome. -
Antibiotic
Leucomycin tartrate is a potent 16-membered macrolide antibiotic that primarily targets bacterial protein synthesis. It exhibits strong antibacterial activity against a range of Gram-positive organisms, making it useful in research applications focused on antimicrobial resistance and the mechanisms of action of antibiotics. This compound is instrumental for studies investigating bacterial infections and developing novel therapeutic strategies. -
Antibiotic
Armeniaspirol B is a selective antibiotic that primarily targets Gram-positive pathogens. It exhibits minimal inhibitory concentration (MIC) values of 0.5 μg/mL against Staphylococcus aureus Newman and 2.0 μg/mL against Staphylococcus aureus USA300. This compound is of particular interest for research focused on Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) infections. -
Antibacterial Agent
Valnemulin is a broad-spectrum antibacterial agent with efficacy against both Gram-positive and Gram-negative bacteria, as well as anaerobic bacteria, Mycoplasma, and Spirochetes. It is primarily utilized in veterinary medicine to treat enteric diseases, acute polyarthritis, and enzootic pneumonia in swine. Additionally, Valnemulin demonstrates anti-inflammatory properties, effectively mitigating lipopolysaccharide-induced lung injury in experimental models. -
Antibiotic
TMC-169 is a potent antibiotic belonging to the Aspochalasin group, isolated from Aspergillus flavipes. This compound demonstrates significant anti-tumor activity across various cancer cell types, making it relevant for research into hematologic malignancies, non-small cell lung cancer, breast cancer, and glioma. TMC-169 serves as a valuable tool for exploring therapeutic strategies against these malignancies. -
Bacteriostatic Antibiotic
Trimethoprim sulfate is a potent bacteriostatic antibiotic that functions primarily as a dihydrofolate reductase inhibitor. It exhibits broad-spectrum activity against various Gram-positive and Gram-negative aerobic bacteria, making it valuable in the study of urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, Trimethoprim sulfate has demonstrated potential in inhibiting Influenza A virus infection in chick embryos when used in combination with zinc, highlighting its multifaceted applications in microbial research. -
Antibiotic/Antimicrobial Peptide
Aurein 2.2 is an antimicrobial peptide that exhibits broad-spectrum antibacterial activity, primarily targeting Gram-positive bacteria including Staphylococcus aureus and S. epidermidis. Isolated from the skin secretions of L. aurea, Aurein 2.2 demonstrates potential as an effective antibiotic, making it a valuable tool for research in microbiology and antimicrobial therapy. Its unique mechanism of action and efficacy against resistant strains underline its relevance in the study of infection control and antibiotic development. -
Macrolide Antibiotic
Aldgamycin G is a macrolide antibiotic that targets Gram-positive bacteria. Isolated from Streptomyces avidinii, it exhibits significant antibacterial activity, making it a valuable compound for research in microbiology and antibiotic resistance studies. Its mechanism of action involves inhibition of bacterial protein synthesis, enhancing its utility in the investigation of microbial pathogenicity and treatment options against Gram-positive infections. -
Antibiotic
LL-Z1220 is a novel antibiotic targeting bacterial cell integrity. Featuring a unique 2-(3,8-dioxopentacyclo[5.1.0.0^~^~]oct-5-en-5-yl)-4H-pyran-4-one structure, it represents the first known natural product containing a benzene dioxide group. LL-Z1220 exhibits valence isomerization, forming 1,4-dioxopentacyclo, with spectral properties indicating a cis configuration of the benzene dioxide moiety. Its distinctive mechanism and structure make it a valuable compound for antibiotic research and development. -
Antibiotic
Daunosamnyl-daunorubicin is an antibiotic that binds to calf thymus DNA, exhibiting significant intercalation properties. This compound is primarily utilized in research focused on anticancer therapies and the study of DNA-drug interactions. Its mechanism of action involves disrupting the normal functioning of DNA, making it valuable for investigations into its therapeutic efficacy against various malignancies. -
Antibacterial Agent
Altromycin D is an antibiotic primarily targeting Gram-positive bacteria. It exhibits significant antibacterial activity, making it a valuable reagent for research applications focused on the study of bacterial resistance and the development of new antimicrobial therapies. Its specific mechanism of action contributes to its efficacy in inhibiting the growth of pathogenic bacteria. -
Quinolone Antibiotic
Lomefloxacin (aspartate) targets bacterial DNA gyrase, exhibiting potent antibacterial activity as a broad-spectrum quinolone antibiotic. It is effective against a wide range of bacterial pathogens and is utilized in research concerning respiratory tract infections, genitourinary infections, gastrointestinal infections, and ENT infections. Its mechanism of action disrupts bacterial DNA replication, making it a valuable tool for investigating antibiotic resistance and treatment efficacy. -
Antibiotic
Spiramycin (hexanedioate) is a macrolide antibiotic derived from Streptomyces ambofaciens, primarily targeting bacterial infections and Toxoplasma gondii. Its chemical structure features a 16-membered lactone ring with three sugar moieties: mycaminose, forosamine, and mycarose. Spiramycin exhibits significant antibacterial and antiparasitic activity, making it valuable in the study of infectious diseases and potential therapeutic applications. -
Antibiotic
BAL-19403 is a macrolide antibiotic that primarily targets bacterial infections. It demonstrates potent activity against Propionibacterium acnes, specifically against strains resistant to erythromycin and clindamycin. BAL-19403 exhibits both antibacterial and anti-inflammatory properties, making it a valuable reagent for research focused on acne treatment and related inflammatory skin conditions. -
Bacterial Inhibitor
Gramicidin C is a polypeptide antibiotic with a primary mechanism of action as a bacterial inhibitor. It disrupts bacterial cell membrane function, resulting in increased permeability that leads to cell lysis. This compound is widely utilized in microbiology research to study bacterial resistance mechanisms and to investigate antibiotic efficacy against various gram-positive and gram-negative bacteria. -
Antibiotic
BU-2313 A is an antibiotic that exhibits antimicrobial activity through its unique dienoyltetraamide acid structure. This compound is related to streptolysin and tilamycin, making it a valuable tool for studying bacterial resistance mechanisms and evaluating potential therapeutic strategies. Its efficacy in combating bacterial infections positions it as a relevant candidate for research in antimicrobial drug development. -
Peptide Antibiotic
Angiotensin III antipeptide is a peptide antibiotic that inhibits the activity of angiotensin II, a key regulator in the renin-angiotensin system. It exhibits biological activity by modulating blood pressure and fluid balance, making it a valuable tool in cardiovascular and renal research. Its applications include studying the effects of angiotensin peptides on physiological processes and exploring potential therapeutic interventions in related diseases. -
Antitumor Antibiotic
Kapurimycin A2 is an antitumor antibiotic derived from the culture of Streptomyces sp., primarily targeting bacterial infections. It exhibits notable antibacterial activity, particularly against Gram-positive bacteria. This compound is utilized in research applications to investigate its potential therapeutic effects in tumor treatment and microbial resistance studies. -
Antibacterial Agent
Antofloxacin is a potent, orally active broad-spectrum 8-amino-fluoroquinolone that serves as an antibacterial agent. It exhibits enhanced activity against gyrA mutation-positive Helicobacter pylori strains, particularly those with Asn87 mutations, outperforming levofloxacin. Additionally, Antofloxacin acts as a weak, reversible inhibitor of CYP1A2, making it a valuable tool for the study of infections caused by various bacterial species. -
Antibiotic
A2315A, also known as Madumycin II, is an alanine-containing streptogramin A antibiotic that functions as a potent inhibitor of the peptidyl transferase center (PTC) within the ribosome. By targeting the ribosomal machinery, A2315A effectively prevents the initiation of the first cycle of peptide bond formation, demonstrating significant antibiotic activity. This compound is valuable for research focusing on ribosomal function and antibiotic mechanism of action. -
Antibiotic/Antimicrobial Peptide
Aurein 2.6 is an antimicrobial peptide that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity, with minimum inhibitory concentrations (MIC) of 25 to 30 μM against various strains, including Micrococcus luteus, Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus mutans, and Bacillus subtilis. Aurein 2.6 is valuable for research applications involving antibiotic resistance studies and the development of new antimicrobial agents. -
Antibiotic
Okilactomycin is a lactone antibiotic derived from the culture filtrate of Streptomyces species. It exhibits antibacterial activity by inhibiting bacterial growth mechanisms, making it valuable for studying antibiotic resistance and bacterial infections. This compound can be utilized in research related to microbiology and pharmacology to further understand antibiotic properties and develop new therapeutic strategies. -
Antibiotic
Boromycin is an antibiotic that targets bacterial ribosomes, inhibiting protein synthesis. Isolated from Streptomyces antibioticus, it exhibits potent activity against a range of gram-positive bacteria. This compound is valuable for research applications related to antimicrobial resistance and the development of new therapeutic agents. -
Peptide Antibiotic
Clavanin A is a peptide antibiotic that disrupts the integrity of the cytoplasmic membrane in target cells. It demonstrates effective bactericidal activity against Micrococcus flavus, making it a valuable tool for studying bacterial membrane dynamics and antibiotic mechanisms. Researchers can utilize Clavanin A for investigations into microbial resistance and the development of new antimicrobial strategies. -
Antibiotic
Altersolanol B, a fungal-derived compound, exhibits antibiotic properties through its ability to induce ATP catabolism in Ehrlich ascites tumor cells. This molecular action highlights its potential as a research tool for studying cellular energy dynamics and responses to antimicrobial agents. Altersolanol B may contribute to the understanding of antibiotic mechanisms and resistance patterns in cancer biology. -
Antibiotic
Ranbezolid is an orally active oxazolidinone antibiotic primarily targeting Gram-positive and Gram-negative anaerobes, including Staphylococcus aureus and Bacteroides fragilis. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, demonstrating an IC50 of 17 μM. Ranbezolid is effective in rapidly reducing bacterial load and has an enhanced cardiovascular safety profile. This compound is valuable for research applications focused on antibiotic effects against anaerobic bacteria. -
Sulfur-containing Antibiotic
Tropodithietic acid is a sulfur-containing antibiotic derived from the marine bacterium Phaeobacter inhibens. It demonstrates potent antibacterial activity against a wide range of bacterial species, including alpha- and gammaproteobacteria, flavobacteria, and actinobacteria. This compound is valuable for research applications involving antimicrobial resistance and the study of microbial interactions in marine environments. -
Antibiotic, Insecticide
Cafamycin is a polyether antibiotic that targets gram-positive bacteria, notably Staphylococcus aureus. In addition to its antibacterial properties, Cafamycin exhibits insecticidal and antiprotozoal activities. It is isolated from the culture fluid of Streptomyces sp., an organism recognized for producing various bioactive compounds, including the anthracycline antibiotic galtamycin. This compound is valuable for research applications in microbiology and pest control. -
Antibacterial Peptide
KT2 is a cationic amphipathic antibacterial peptide that targets bacterial membranes. It exhibits potent antibacterial activity against E. coli O157:H7, demonstrating complete bactericidal effects and significant inhibition of biofilm formation. KT2 interacts with bacterial surface lipopolysaccharides (LPS) and penetrates lipid layers, facilitating its binding to DNA and other cytoplasmic components, making it a valuable reagent for research in antimicrobial therapies and biofilm-related studies. -
Bacterial Inhibitor
Anhydroerythromycin A is a bacterial inhibitor derived from the degradation of the macrolide antibiotic erythromycin. It exhibits antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentrations of 12.5 µg/ml and 6.25 µg/ml, respectively. Additionally, Anhydroerythromycin A inhibits steroid 6β-hydroxylase activity linked to the cytochrome P450 isoform CYP3A in human liver microsomes, making it a valuable tool for studying bacterial resistance and metabolic pathways.
