Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
Tembetarine chloride is an alkaloid derived from Tinospora cordifolia, primarily acting as an antibacterial agent. It demonstrates significant antibacterial activity while exhibiting weak cytotoxicity against mouse fibroblasts (L929) and human embryonic kidney cells (HEK293), with IC50 values of 1245.33 μg/mL and 1642.81 μg/mL, respectively. This compound is suitable for research applications focused on understanding antibacterial mechanisms and evaluating cytotoxic effects in cellular models. -
Anti-Bacterial Agent
Grahamimycin B is an anti-bacterial agent with demonstrated weak activity against Gram-positive bacteria, as well as varying effects on Gram-negative bacteria, cyanobacteria, and green algae. Its unique biochemical properties make it a valuable compound for research in microbial inhibition and the study of bacterial resistance mechanisms. Grahamimycin B serves as a useful tool in investigations related to antibiotic development and the ecological impact of microbial communities. -
Anti-Bacterial Agent
Neoviridogrisein II is an anti-bacterial agent that exhibits activity against Gram-positive bacteria and mycoplasma. Its mechanism involves disrupting cellular processes in target organisms, making it a valuable compound for research applications focused on the development of novel antibacterial therapies and the study of bacterial resistance mechanisms. Neoviridogrisein II is ideal for investigations seeking to understand bacterial pathogenesis and the efficacy of antimicrobial treatments. -
Anti-Bacterial Agent
Cirramycin B1 is an anti-bacterial agent effective against Gram-positive and Gram-negative bacteria, as well as mycoplasmas. This compound demonstrates strong antimicrobial activity, making it a valuable reagent for research focused on combating bacterial infections and studying antibiotic resistance mechanisms. Its broad spectrum of activity supports investigations in microbiology and pharmacology. -
Anti-bacterial Agent
Diaporthin is a phytotoxin derived from Cryphonectria parasitica, exhibiting potent antibacterial properties. This compound is effective against various bacterial strains, making it a valuable tool for studies focused on antimicrobial activity and resistance. Its unique mechanism of action positions Diaporthin as a significant candidate for research in the development of new antibacterial agents. -
Anti-Bacterial Agent
Megovalicin D is an anti-bacterial agent known for its efficacy against Bacillus subtilis and Escherichia coli, as well as its inhibitory action on Pseudomonas aeruginosa. This compound is critical for research applications focused on combating bacterial infections and studying the mechanisms of bacterial resistance. Its broad-spectrum activity makes it a valuable tool in microbiological research and antibiotic development. -
Bacterial Inhibitor
Lysine hydroxamate is an amino acid hydroxamate that acts as a bacterial inhibitor by selectively reducing the growth of Escherichia coli K-12. This compound demonstrates significant antibacterial activity among amino acid hydroxamates, with a unique mechanism of action that allows for the reversible inhibition of bacterial growth through the addition of L-serine. Lysine hydroxamate provides a valuable tool for researchers investigating bacterial growth inhibition and exploring amino acid analogs in microbial studies. -
Antifbacterial Agent
Antibacterial Agent 323 is characterized as an antibacterial compound with modest activity against bacterial pathogens. It has potential applications in the study of bacterial infections, specifically targeting strains of Acinetobacter baumannii. Researchers can utilize this reagent to explore mechanisms of resistance and evaluate therapeutic strategies for combating bacterial diseases. -
Antibacterial Agent
2-Quinoxalinecarboxylic acid is an antibacterial agent specifically targeting Mycobacterium tuberculosis with a minimum inhibitory concentration (MIC) greater than 128 µg/mL. This compound shows potential in the study of tuberculosis, contributing to the development of new therapeutic strategies against this persistent pathogen. -
Anti-Bacterial Agent
Granaticin A functions as an anti-bacterial agent by inhibiting the initial stages of RNA biosynthesis. It exhibits activity against Gram-positive bacteria and demonstrates weak inhibitory effects on Mycobacterium and Vaginal trichomonas. Additionally, Granaticin A has potential applications in cancer research due to its ability to inhibit tumor cell proliferation. -
Anti-Bacterial Agent
Empedopeptin is an anti-bacterial agent targeting Gram-negative bacteria. It exhibits significant activity against a range of these pathogens, making it a valuable reagent for research in microbiology and infectious disease studies. Its mechanism of action and efficacy position it as a promising candidate for further exploration in the development of new antimicrobial therapies. -
Anti-Bacterial Agent
Citreamicin β is an anti-bacterial agent that exhibits potent activity against Gram-positive aerobic and anaerobic bacteria. This compound is particularly useful in microbiological research for investigating bacterial resistance mechanisms and the efficacy of antibacterial therapies. Its targeted action provides valuable insights into the development of new antibacterial strategies. -
Antibacterial Agent
Antibacterial Agent 303 is an antibacterial compound that demonstrates significant efficacy against multidrug-resistant strains, particularly with minimum inhibitory concentrations (MICs) of 10 and 100 µg/mL against Pseudomonas aeruginosa MDR1 and Staphylococcus aureus MDR strains, respectively. This agent exhibits strong binding affinities for E. coli DNA gyrase and Candida albicans lanosterol 14α-demethylase. Antibacterial Agent 303 is suitable for research focused on drug-resistant infections, providing valuable insights into combating antimicrobial resistance. -
Antibacterial Agents
CAP 3 is a cholic acid-peptide conjugate that acts as an effective antibacterial agent targeting Gram-negative bacteria. It demonstrates potent antibacterial activity with minimum inhibitory concentration (MIC99) values of 8 μM, 16 μM, and 16 μM against E. coli, Klebsiella pneumoniae, and Acinetobacter baumannii, respectively. CAP 3 functions by disrupting the structural integrity of bacterial lipopolysaccharide (LPS) outer membranes, leading to rapid bacterial cell death. Additionally, it inhibits biofilm formation and shows efficacy against drug-resistant strains, making it valuable for addressing persistent bacterial infections in research settings. -
Anti-Bacterial Agent
Kerriamycin A is a potent anti-bacterial agent targeting Gram-positive bacteria. This compound exhibits significant antibacterial activity and has also been shown to inhibit ascites cancer in animal models, making it valuable for further research in infectious diseases and cancer therapy. Its dual mechanism offers promising avenues for studies in therapeutic applications. -
Anti-Bacterial Agent
Megovalicin H is a potent antibacterial agent that targets a broad spectrum of bacteria, including Bacillus subtilis and Escherichia coli, as well as Pseudomonas aeruginosa. Its efficacy in inhibiting bacterial growth makes it a valuable reagent for microbiological studies and research into antibiotic resistance mechanisms. Megovalicin H is suitable for applications in both basic and applied microbiology. -
Antibiotic
Istamycin Y0 is an aminoglycoside antibiotic with primary activity against bacterial ribosomes. Isolated from Streptomyces tenjimariensis ATCC 31603, it exhibits limited antibacterial efficacy against select bacterial strains. Istamycin Y0 is primarily used in microbiological research to study antibiotic resistance mechanisms and the pharmacodynamics of aminoglycosides. -
Bacterial Metabolite
ε-Rhodomycinone is a bacterial metabolite derived from Streptomyces griseoruber that acts as a precursor to Rhodomycin D. This compound plays a critical role in the bioconversion pathway leading to the production of clinically relevant anthracycline antibiotics, including Daunorubicin and Doxorubicin. Its study is significant for understanding antibiotic biosynthesis and developing novel therapeutic agents. -
Bacterial Inhibitor
Negamycin is a bacterial inhibitor that targets protein synthesis by binding to the head domain of the bacterial ribosomal small subunit. This interaction disrupts normal translation, leading to cell death and enhancing the misreading of near-cognate codons. Negamycin is valuable for research applications focused on understanding antibiotic mechanisms and bacterial resistance. -
Anti-Bacterial Agent
Lunatoic acid A functions as an anti-bacterial agent with notable effects against specific bacterial strains. In addition to its antibacterial properties, this compound also exhibits partial anti-mould activity. It is applicable in research focused on microbial inhibition and the development of antimicrobial therapies. -
Anti-Bacterial Agent
γ-Chloronorvaline is an anti-bacterial agent that exhibits resistance against Pseudomonas aeruginosa, Serratia, Klebsiella pneumoniae, and Bacillus subtilis in synthetic media. This compound is particularly useful in research applications focused on combating infections caused by these specific pathogens. Notably, it shows no activity against Escherichia coli, making it a selective agent for targeted bacterial strains. -
Anti-Bacterial Agent
3-epi-Deoxynegamycin is an antibacterial agent that primarily targets Gram-positive bacteria. It exhibits significant antibacterial activity against a wide range of Gram-positive strains, while displaying limited efficacy against Gram-negative bacteria. This compound is valuable for research applications focused on understanding bacterial resistance and developing new therapeutic strategies against bacterial infections. -
Antibacterial Agent
PGE 9262932 is a quinolone antibacterial agent that targets bacterial DNA gyrase and topoisomerase IV, disrupting core processes of bacterial replication. This compound exhibits significant antibacterial activity, making it suitable for research applications focused on infections caused by a variety of bacterial pathogens. It serves as a valuable tool in the study of bacterial resistance mechanisms and the development of novel antimicrobial therapies. -
Bacterial Inhibitor
3-Fluoro-DL-valine is an unnatural amino acid that functions as a bacterial inhibitor by disrupting protein synthesis in targeted bacterial strains. This compound demonstrates significant antibacterial activity, making it a valuable tool in microbiological studies. Additionally, 3-Fluoro-DL-valine can be utilized in peptide synthesis, offering versatile applications for the development of bioactive peptides in biochemical research and drug discovery. Its distinct structural properties position it as a promising candidate for innovative compound research and development. -
Antibacterial Agent
Dapabutan is an antimicrobial agent primarily targeting Gram-positive bacteria. It exhibits potent antibacterial activity, making it suitable for research focused on the development of novel treatments for bacterial infections. Its mechanism of action involves disrupting bacterial cell wall synthesis, thereby inhibiting growth and proliferation. This compound is valuable for studies in microbiology and pharmaceutical development. -
MRSA Antibiotic
MRSA Antibiotic 2 selectively targets methicillin-resistant Staphylococcus aureus (MRSA) with a minimum inhibitory concentration (MIC) of 2 μg/mL. This compound demonstrates enhanced efficacy against Gram-positive bacteria while exhibiting minimal impact on Gram-negative bacteria and human cells. It is a valuable tool in the study of antibiotic resistance and the development of new therapeutic strategies for treating MRSA infections. -
Anti-Bacterial Agent
Pyloricidin A is an antibiotic that specifically targets Helicobacter pylori, derived from Bacillus sp. HC-70. It exhibits potent anti-H. pylori activity, making it a valuable reagent for studying this pathogen. Pyloricidin A is selective and shows no activity against other bacterial strains or yeast, providing a focused approach for research applications related to H. pylori infections. -
Anti-Bacterial Agent
Dihydrogranaticin is an anti-bacterial agent targeting Bacillus cereus. It exhibits significant antimicrobial activity, making it a valuable tool in the study and development of treatments against bacterial infections. This compound is suitable for research applications focused on antimicrobial resistance and the efficacy of new antibacterial therapies. -
Anti-Bacterial Agent
Coumermycin A2 is an anti-bacterial agent that primarily targets Gram-positive bacteria, displaying weak activity against mycobacterium. This compound has significant applications in research focused on bacterial resistance and the development of novel antibacterial therapies. Its mechanism of action involves inhibition of bacterial growth, providing a valuable tool for studies in microbiology and drug discovery. -
Antibacterial Agent
KY-9 is an antibacterial agent that functions by inhibiting bacterial growth through its targeted mechanism of action. This compound exhibits notable efficacy against a range of Gram-positive and Gram-negative bacteria. As a result, KY-9 serves as a valuable tool in microbiological research and the development of antimicrobial therapies. -
Bacterial
Flambalactone is a degradation product derived from the methanolysis of the antibiotic flambamycin. It targets bacterial systems and exhibits inhibitory activity against various strains of pathogenic bacteria. This compound is useful in research applications focused on understanding antibiotic resistance mechanisms and bacterial cell viability. -
Antibacterial Agent
LB 10517 (sodium) is a cephalosporin antibiotic known for its broad-spectrum antibacterial activity. It effectively targets both Gram-positive and Gram-negative bacteria, including notable pathogens such as Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus, and Streptococcus. This compound is valuable for research applications focused on bacterial infections and antibiotic resistance mechanisms. -
Anti-Bacterial Agent
9-Hydroxycrisamicin, an anti-bacterial agent, exhibits weak activity against Gram-positive bacteria with a minimum inhibitory concentration (MIC) ranging from 6.25 to 25 μg/mL. Additionally, 9-Hydroxycrisamicin demonstrates significant growth inhibition in various human tumor cell lines, making it a valuable compound for research in both antibacterial and oncological studies. -
Anti-Bacterial Agent
Kigamicin A is an anti-bacterial agent with demonstrated efficacy against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Its minimum inhibitory concentrations (MICs) range from 0.025 to 0.78 μg/mL, indicating potent antibacterial activity. This compound is valuable in research focused on combating antibiotic-resistant bacterial infections and exploring new therapeutic options. -
Antibacterial Agent
PYO12 is a selective antibacterial compound targeting Gram-positive bacteria. It demonstrates potent activity against S. aureus, B. subtilis, S. pneumoniae, and MRSA, with minimum inhibitory concentrations (MIC) of 1 μg/mL for the first three and 4 μg/mL for MRSA. PYO12 enhances bacterial membrane permeability and upregulates stress-related genes by potentially binding to the C55-PP moiety of lipid II. Its concentration-dependent bactericidal effect, coupled with low toxicity to mammalian cells and lack of hemolytic activity, positions PYO12 as a promising candidate for the development of novel antibiotics focused on bacterial cell wall synthesis. -
Polyketide
Reveromycin C is a polyketide compound originally derived from Streptomyces, exhibiting significant antifungal activity against Candida albicans, with minimum inhibitory concentrations of 2.0 μg/mL at pH 3 and above 500 μg/mL at pH 7.4. It inhibits EGF-induced mitogenic activity in Balb/MK mouse epidermal cells and effectively reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells with an EC50 of 1.58 μg/mL. Additionally, Reveromycin C suppresses the proliferation of KB cells and K562 human chronic myelogenous leukemia cells, both with an IC50 of 2.0 μg/mL, making it a valuable tool for cancer research and antifungal studies. -
Antibacterial Agent
ML370 is an antibacterial agent that functions by inhibiting the activity of the Vibrio cholerae LuxO kinase. This inhibition disrupts bacterial signaling, thereby impeding the growth and virulence of cholera pathogens. ML370 is suitable for research applications focused on infectious diseases, particularly in studies related to cholera and other Vibrio species. -
Anti-Bacterial Agent
Emerimicin III is an anti-bacterial agent primarily targeted against Gram-positive bacteria. This compound exhibits potent inhibitory effects, making it a valuable tool in research focused on bacterial infections and resistance mechanisms. Its unique structure and activity profile facilitate studies into novel therapeutic approaches for combatting Gram-positive pathogens. -
Anti-Bacterial Agent
Hazimycin 5 is an anti-bacterial agent with demonstrated activity against Gram-negative bacteria, as well as select yeast and skin fungi. This compound is useful in research applications focused on identifying and characterizing the mechanisms of bacterial resistance and the effects of antimicrobial agents. Its weak activity profile makes it particularly relevant in studies exploring the efficacy of combination therapies or the development of new antimicrobial compounds. -
Antibacterial Agent
Antibacterial agent 311 targets bacterial infections through its potent antibacterial activity. It demonstrates efficacy against clinically relevant pathogens, including Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, and resistant strains such as E. CTXM1 and E. NDM1, with minimal inhibitory concentrations (MICs) ranging from 0.7 to 1 mg/mL. This compound is valuable for research applications focused on antimicrobial resistance and the development of novel antibacterial therapies. -
Anti-Bacterial Agent
Curvulic acid is an anti-bacterial agent that exhibits modest inhibitory activity against both Gram-positive and Gram-negative bacteria. Its biological activity makes it a potential candidate for research in antimicrobial studies and the development of new antibacterial therapies. This compound can be utilized in investigations focusing on bacterial resistance mechanisms and the evaluation of novel antibacterial agents. -
Bacterial Inhibitor
WQ3810 is a fluoroquinolone antibiotic that acts by inhibiting bacterial DNA gyrase and topoisomerase IV, critical enzymes for DNA replication and transcription. This compound exhibits potent antibacterial activity against a range of gram-positive and gram-negative bacteria. WQ3810 is valuable for research applications focused on studying bacterial infections and developing effective antimicrobial therapies. -
Bacterial Inhibitor
Vebufloxacin is a synthetic antibacterial agent that targets bacterial DNA gyrase, leading to the inhibition of bacterial DNA replication and transcription. It demonstrates potent activity against both gram-positive and gram-negative bacteria, making it a valuable tool in studying bacterial infections and resistance mechanisms. Research applications include evaluating the efficacy of antibacterial treatments and understanding the molecular basis of bacterial survival. -
Bacterial Inhibitor
BO3482 is a bacterial inhibitor that exhibits antimicrobial activity against methicillin-resistant Staphylococci (MRS). It demonstrates a minimum inhibitory concentration (MIC90) of 6.25 mg/mL, effectively halting bacterial growth. This compound is valuable for research applications focused on antibiotic resistance and the development of new antibacterial agents. -
Bacterial Inhibitor
A7132 is a potent antibacterial agent that targets bacterial infections. This compound exhibits broad-spectrum antibacterial activity, making it a valuable tool for research applications in antimicrobial studies and the development of new therapies against bacterial resistance. A7132 is suitable for evaluating the efficacy of antibacterial compounds in various biological assays. -
Antiviral Agent
Amustaline is an antiviral agent that functions as a nucleic acid-targeted chemical decontaminant. It effectively inactivates a range of pathogens, particularly mosquito-borne viruses such as Chikungunya virus (CHIKV), Dengue virus (DENV), and Zika virus (ZIKV). When used in conjunction with glutathione (GSH), Amustaline maintains the integrity of red blood cell membranes, enhancing its safety profile. This compound is primarily applied in the inactivation of pathogens in red blood cell concentrates (RBCC), significantly mitigating the risk of transfusion-transmitted infections (TTI). -
HIV Replication Inhibitor
PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication, demonstrating significant antiviral activity. In addition to its efficacy against HIV, PMEDAP exhibits anti-murine cytomegalovirus (MCMV) properties and effectively inhibits Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality. This compound is valuable for research applications focused on viral pathogenesis and therapeutic interventions in retroviral infections. -
Anti-HIV Synthetic Peptides
T-22 is an anti-HIV synthetic peptide that specifically targets viral entry by disrupting the fusion process of the virus with host cells. Demonstrating potent antiviral activity with an EC50 of 0.008 μg/mL, T-22 exhibits a CC50 of 54 μg/mL, indicating its relative safety for cellular application. In addition to its antiviral properties, T-22 has been shown to enhance plant growth, photosynthesis, total chlorophyll content, and gas exchange in tomatoes, as well as provide resistance against Cucumber Mosaic Virus (CMV). This multifunctional peptide serves as a valuable tool in both virology and agricultural research. -
TRPML Agonist
ML-SA1 is a selective agonist of TRPML channels, promoting lysosomal acidification and enhancing protease activity, which leads to the inhibition of Dengue virus 2 (DENV2) and Zika virus (ZIKV). The compound exhibits IC50 values of 8.3 μM for DENV2 RNA and 52.99 μM for ZIKV RNA. Additionally, ML-SA1 stimulates autophagy, making it a valuable tool for research into broad-spectrum antiviral strategies. -
Dengue Virus Inhibitor
Mosnodenvir is an orally active pan-serotype inhibitor of the dengue virus (DENV), exhibiting EC50 values between 0.057 and 11 nM across four DENV serotypes. Its primary mechanism involves inhibiting the interaction between nonstructural proteins NS3 and NS4B, which is critical for preventing the replication of viral RNA. With demonstrated picomolar to nanomolar antiviral activity in vitro, Mosnodenvir also shows antiviral efficacy in murine and non-human primate models, making it a valuable tool for research into dengue virus treatment.
