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HIV-1-IN-88

Catalog No.: A51725
HIV‑1 Protease Inhibitor
HIV-1-IN-88 is a potent HIV-1 protease inhibitor, demonstrating an IC50 value of 10 pM and an antiviral EC50 value of 10.4 nM. This compound retains efficacy against multidrug-resistant HIV-1 variants, including HIV-1Muta and HIV-1I50V, with EC50 values of 30.0 nM and 34.3 nM, respectively. HIV-1-IN-88 serves as a valuable tool for research aimed at understanding and combating HIV infection and resistance mechanisms.
HIV-1-IN-88 2459707-59-4 HIV‑1 Protease Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionHIV-1-IN-88 is a potent HIV-1 protease inhibitor, demonstrating an IC50 value of 10 pM and an antiviral EC50 value of 10.4 nM. This compound retains efficacy against multidrug-resistant HIV-1 variants, including HIV-1Muta and HIV-1I50V, with EC50 values of 30.0 nM and 34.3 nM, respectively. HIV-1-IN-88 serves as a valuable tool for research aimed at understanding and combating HIV infection and resistance mechanisms.
Product Information
Catalog NumA51725
FormulaC32H44N4O10S
Molecular Weight676.78
CAS Number2459707-59-4
SMILESO[C@@H]([C@@H](NC([C@H](CC(N)=O)NC(O[C@@]1([C@]2([C@@]([H])(OC1)OCC2)[H])[H])=O)=O)CC3=CC=CC=C3)CN(CC(C)C)S(=O)(C4=CC=C(C=C4)OC)=O
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Microbiology > Antifection > HIV