Antifection

Items 4301-4350 of 4946

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  1. Anti-Bacterial Agent

    Azirinomycin is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. Its mechanism of action involves the inhibition of bacterial protein synthesis, making it a valuable tool in the study of bacterial infections and resistance mechanisms. This compound holds potential for the development of novel therapeutic strategies in combating bacterial pathogens.
  2. Anti-Bacterial Agent

    Naphthomycin A is an anti-bacterial agent that primarily targets Gram-positive bacteria and fungi. It functions by inhibiting fatty acid synthesis in coliform bacteria, making it a valuable tool for studying bacterial resistance and metabolic pathways. This compound is suitable for research applications in microbiology and pharmacology, particularly in developing antibiotic compounds.
  3. Antibacterial Agent

    (E)-Nitrofurazone, a topical broad-spectrum antibacterial agent, targets both Gram-negative and Gram-positive bacteria. It also exhibits antiprotozoal and antiparasitic activities. This compound is utilized in research related to superficial wounds, burns, skin infections, pyoderma, infectious skin diseases, as well as conditions such as trypanosomiasis and acute bacillary dysentery.
  4. Anti-Bacterial Agent

    Dihydrodaunomycin is an anti-bacterial agent that exhibits significant antibacterial and antitumor properties. It is effective in research applications aimed at elucidating mechanisms of action against bacterial infections and cancer cell proliferation. Its dual activity makes it a valuable compound for studying the interplay between antibacterial and antitumor effects in various biological contexts.
  5. Bacterial Metabolite

    Deoxyenterocin is a bacterial metabolite obtained from Streptomyces, primarily known for its diverse biological activities, including antibiotic, antiviral, and antioxidant effects. It exhibits significant antibacterial activity by inhibiting the growth of pathogens such as S. lutea, S. aureus, K. pneumoniae, and V. percolans at a concentration of 500 μg/mL. Additionally, deoxyenterocin demonstrates antiviral properties, reducing the cytopathic effect of influenza A H1N1 by 60.6% at 50 μg/mL. Moreover, at a concentration of 1 μM, it protects mouse primary cortical neurons from hydrogen peroxide-induced oxidative stress by preserving glutathione levels and mitochondrial membrane potential.
  6. Anti-Bacterial Agent

    Ochracenomicin A is an anti-bacterial agent that exhibits potent activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), as well as Gram-negative bacteria and Candida albicans. This compound is valuable for research applications aimed at investigating bacterial resistance mechanisms and developing new antimicrobial therapies. Its broad-spectrum efficacy makes it a key reagent in studies focused on bacterial infections and potential treatments.
  7. Anti-Bacterial Agent

    Piloquinone is a phenanthrene derivative that exhibits antibacterial activity primarily against mycobacteria and certain protozoa. While its inhibitory effects are not exceptionally potent, it serves as a valuable tool for research applications targeting microbial resistance and the study of antimicrobial mechanisms. This compound may assist in understanding the biochemical pathways involved in bacterial infection and resistance.
  8. LasB Inhibitor, Antibacterial Activity

    Elastase LasB-IN-1 is a selective inhibitor of elastase LasB, exhibiting a potent IC50 value of 76 nM. This compound demonstrates significant antibacterial activity, making it an important tool for research applications focused on bacterial infections. Its specificity for LasB facilitates investigations into the role of elastolytic enzymes in microbial pathogenesis.
  9. Antibiotic

    2-Hydroxyaclacinomycin B is an anthracycline antibiotic known for its ability to inhibit RNA synthesis. Isolated from Streptomyces galilaeus A-862 (FERM BP-45), this compound exhibits significant anti-tumor activity. It serves as a valuable tool in cancer research, enabling studies focused on mechanisms of action and therapeutic potential within oncology.
  10. Bacterial Inhibitor

    Antibacterial agent 149 is a potent laccase inhibitor that exhibits significant antibacterial properties. This compound is particularly effective against bacterial pathogens and has demonstrated high fungicidal activity, making it a valuable tool for studying rice sheath blight and related diseases. Its mechanism of action and specificity enhance its utility in researching bacterial inhibition and plant pathogenic interactions.
  11. Anti-Bacterial Agent

    Bamicetin is an anti-bacterial agent that primarily targets Gram-positive bacteria and Mycobacteria. It exhibits significant activity against various strains, making it a valuable tool for research in microbial resistance and infectious disease studies. Its efficacy in combating these pathogens supports its use in investigations focused on antibiotic development and bacterial virulence mechanisms.
  12. Antifungal Agent

    Ayapin is a phytoalexin primarily derived from sunflower, functioning as a potent antifungal agent. It effectively inhibits the growth of Sclerotinia sclerotiorum, exhibiting an IC50 value of 0.16 mM for 50% inhibition. Ayapin is valuable for research applications focused on the mechanisms of antifungal resistance and strategies to combat sclerotinia infections.
  13. Anti-Bacterial Agent

    4-Diazo-3-methoxy-2,5-cyclohexadien-1-one primarily targets bacterial cells to exert its anti-bacterial activity. It demonstrates effective inhibition against anaerobic bacteria, with a minimum inhibitory concentration (MIC) of 0.4 μg/mL for Clostridium and Bacteroides, and 0.2 μg/mL for Haemophilus. This compound is suitable for research applications focused on developing antibacterial agents and understanding mechanisms of bacterial resistance.
  14. Antibacterial Agent

    2-Acetylthiophene thiosemicarbazone acts as an antibacterial agent, demonstrating significant efficacy against various bacterial strains. Additionally, it exhibits anticancer activity, with an IC50 value of 8.6 μM against HT-29 colon cancer cells. This compound is suitable for research applications focusing on antibacterial and anticancer mechanisms.
  15. Bacterial Inhibitor

    15-Methylhexadeca Sphinganine is an iso-branched sphingolipid that acts as a bacterial inhibitor. It is identified as a component of ceramide-containing phospholipids in bacterial cell membranes. This compound is valuable for research applications focused on understanding bacterial lipid metabolism and exploring potential therapeutic strategies against bacterial infections.
  16. Anti-Bacterial Agent

    Chrysospermin C is an antibacterial agent with demonstrated activity against various Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, as well as the pathogen Klebsiella pneumoniae. Additionally, it exhibits efficacy against individual yeast strains such as Ocher echinoderma and Saccharomyces cerevisiae. This compound is valuable for research applications focusing on antimicrobial resistance and infection control.
  17. Anti-Bacterial Agent

    Cephaibol A is an anti-bacterial agent primarily effective against Gram-positive bacteria. It demonstrates significant activity in targeting infections caused by sensitive Gram-positive strains while showing no efficacy against Gram-negative bacteria. Additionally, Cephaibol A exhibits properties that aid in deworming and combating ectoparasitic infestations. This versatility makes it a valuable tool in research focused on bacterial infections and parasitic diseases.
  18. Anti-Bacterial Agent

    Saquayamycin C1 is an anti-bacterial agent with significant antimicrobial properties. It demonstrates a pronounced inhibitory effect on leukemia P388 cells as well as Adriamycin-resistant P388 cells, making it a valuable compound for cancer research. Its selective activity, particularly against specific cancer cell lines, underscores its potential applications in exploring therapeutic strategies targeting resistant leukemia. However, it shows a weaker effect against Gram-negative bacteria, indicating a selectivity that may be beneficial in tailored antibiotic research.
  19. Anti-Bacterial Agent

    Chloroquinocin is an anti-bacterial agent that exhibits moderate activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). This compound is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing new therapeutic strategies against resistant strains. Its targeted action makes it a significant tool for researchers focusing on infections caused by resilient bacterial pathogens.
  20. Anti-Bacterial Agent

    Papyracon D, an anti-bacterial agent, demonstrates a modest inhibitory effect on L1210 and HL60 cell lines, indicating potential cytotoxicity in certain cancer research applications. Additionally, Papyracon D exhibits weak antibacterial activity against Gram-positive bacteria and some nematodes. Its biological activities may be explored in studies focusing on bacterial resistance and cancer cell modulation.
  21. Antibacterial Agnet

    Carfecillin sodium is an orally active phenyl ester of carbenicillin that functions as an antibacterial agent. It exhibits significant antibacterial activity, making it suitable for research on urinary tract infections and related microbial studies. Its profile allows for exploration in clinical settings focused on antibiotic efficacy and resistance patterns.
  22. Antibacterial Agent

    Celesticetin is an antibacterial agent that targets and inhibits the growth of Sulfolobus acidocaldarius. It demonstrates significant bactericidal activity, making it useful in studying microbial dynamics and mechanisms of antibacterial resistance. Its application extends to various research areas, including microbiology and biochemistry, facilitating the exploration of bacterial cell processes.
  23. Anti-Bacterial Agent

    Griseolutein B is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. This compound is useful in studies focused on bacterial infection mechanisms and the development of new antimicrobial therapies. Its broad-spectrum efficacy makes it a valuable tool for researchers investigating bacterial resistance and treatment options.
  24. Anti-Bacterial Agent

    Monorden B is an anti-bacterial agent that disrupts the cell cycle in Jurkat cells, effectively halting progression in both G1 and G2/M phases. This compound demonstrates notable anti-Aspergillus niger activity, making it a valuable tool for research in microbiology and cell cycle regulation. Its unique mechanism of action may provide insights into therapeutic strategies against bacterial infections and fungal pathogens.
  25. Antibacterial Agent

    (E)-2-(4-Cinnamoylphenoxy)acetic acid functions as an antibacterial agent. It exhibits potent antimicrobial activity, demonstrating a minimum inhibitory concentration of 125 μg/mL against various pathogens, including Mycobacterium smegmatis, Staphylococcus aureus, and Candida albicans. This compound is valuable for research applications focused on antimicrobial resistance and the development of new therapeutic agents.
  26. Anti-Bacterial Agent

    Fomecin A is an anti-bacterial agent that exhibits significant activity against Gram-positive bacteria, with weaker effects observed against Gram-negative bacteria and fungi. Its mechanism of action involves disruption of bacterial cell wall synthesis, making it a valuable tool for research focused on combating bacterial infections. Fomecin A can be utilized in studies exploring the efficacy of new antimicrobial compounds and their potential applications in clinical settings.
  27. Anti-Bacterial Agent

    2"-N-Formimidoylsporaricin A is an anti-bacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria, including strains resistant to aminoglycosides. This compound demonstrates potent antibacterial properties, making it a valuable tool for microbiological research and the development of new therapeutic strategies against resistant bacterial infections. Its broad-spectrum efficacy positions it as a significant candidate for studies focused on antimicrobial resistance and therapeutic intervention.
  28. Anti-Bacterial Agent

    Azicemicin A is an antibacterial agent that exhibits weak antibacterial activity. It has been shown to possess no acute toxicity in mouse models, making it a potential candidate for further research in antibiotic development and safety assessments. Its unique properties may facilitate investigations into the mechanisms of antibiotic action and resistance.
  29. Anti-Bacterial Agent

    Megovalicin B is an anti-bacterial agent that exhibits potent activity against Bacillus subtilis and Escherichia coli. This compound is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing novel antibacterial therapies. Its efficacy in inhibiting pathogenic microbial growth makes it an important tool in microbiology and pharmaceutical development.
  30. Anti-Bacterial Agent

    Ostreogrycin B3 is an anti-bacterial agent targeting Gram-positive bacteria. This compound exhibits significant inhibitory effects against various strains, making it suitable for studies in microbial resistance and antibacterial efficacy. It is a valuable reagent for research applications focused on developing new therapeutics for bacterial infections.
  31. Antibacterial Agent

    VPC162134 is an antibacterial agent that targets and inhibits pyruvate ferredoxin oxidoreductase (PFOR), showing effectiveness against H. pylori, C. jejuni, MRSA, and S. epidermidis with minimum inhibitory concentrations (MIC) of 2.9, 17.5, 93.3, and 93.3 μM, respectively. Its notable antibacterial properties make it useful for research in combating antibiotic-resistant bacteria and understanding microbial resistance mechanisms.
  32. Bacterial

    2,3-Diphenylquinoxaline-6-sulphonamide acts as an antibacterial agent targeting bacterial pathways. This compound demonstrates significant antibacterial activity, making it suitable for research applications focused on bacterial infections. Additionally, it exhibits analgesic and anti-inflammatory properties, providing insights into its potential therapeutic roles beyond antimicrobial effects.
  33. Anti-Bacterial Agent

    Cerexin D4 is an anti-bacterial agent targeting Gram-positive bacteria. It exhibits significant activity against various strains, making it a valuable tool in the study of bacterial infections and the development of new therapeutic strategies. Researchers can utilize Cerexin D4 in investigations related to antibiotic resistance and the efficacy of antibacterial compounds.
  34. Anti-Bacterial Agent

    Chrysospermin B is an anti-bacterial agent that demonstrates significant activity against various Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, as well as the pathogen Klebsiella pneumoniae. Additionally, it exhibits efficacy against specific yeasts such as Ocher echinoderma and Saccharomyces cerevisiae. This compound is valuable for investigations into bacterial and fungal infections and the development of new antimicrobial therapies.
  35. Anti-Bacterial Agent

    Glucosylquestiomycin is an anti-bacterial agent that targets both Gram-positive and Gram-negative bacteria, as well as yeast. Its broad-spectrum activity makes it a valuable tool in microbiological research and the development of new antimicrobial therapies. Researchers can utilize Glucosylquestiomycin to investigate bacterial resistance mechanisms and explore potential applications in infection control.
  36. Bacterial

    Linearmycin A is a polyene antibiotic targeting bacterial pathogens, derived from Streptomyces. It demonstrates significant antimicrobial activity against Staphylococcus aureus and Escherichia coli, with minimum inhibitory concentrations (MICs) of 3.1 and 1.6 μg/disc, respectively. Additionally, Linearmycin A exhibits antifungal properties, inhibiting Saccharomyces cerevisiae and Candida albicans with MICs of 0.1 and 1.6 μg/disc, respectively, and also shows effectiveness against the plant pathogenic fungus Aspergillus niger (MIC=0.2 μg/disc). This compound is valuable in research applications focused on bacterial and fungal infections, as well as the mechanisms of antibiotic action.
  37. Anti-Bacterial Agent

    Carpetimycin A is a potent anti-bacterial agent that demonstrates robust activity against both Gram-positive and Gram-negative bacteria, including strains that produce β-lactamase. This compound effectively inhibits β-lactamase activity, making it a valuable tool for research focused on antibiotic resistance mechanisms and potential therapeutic development. Its broad-spectrum efficacy positions Carpetimycin A as an important reagent for studies in microbiology and infectious disease.
  38. Antibacterial Agent

    HT-61 is a quinolone antibacterial agent that demonstrates potent bactericidal activity against gram-positive bacteria, including both methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). This compound shows potential in enhancing the efficacy of Tobramycin against Pseudomonas aeruginosa, making it a valuable tool for research on antibiotic resistance and mechanisms of bacterial infection. Its applications span microbiological studies and the development of novel antibacterial therapies.
  39. Anti-mycotic Agent

    Tioxaprofen is an effective anti-mycotic agent that targets Trichophyton mentagrophytes and T. rubrum. Its primary mechanism of action involves acting as a potent uncoupling agent of mitochondrial respiration, disrupting the energy production in fungal cells. This compound is valuable for research focused on fungal infections and mitochondrial function, providing insights into potential therapeutic avenues.
  40. Antibacterial Agent

    Apalcillin sodium is an antibacterial agent effective against carbenicillin- and ampicillin-resistant strains of gram-negative bacilli. It functions by inhibiting bacterial cell wall synthesis, demonstrating significant activity in combating various bacterial infections. This reagent is particularly useful in research applications focused on antibiotic resistance and the development of new antibacterial therapies.
  41. Antibacterial Agent

    HMRZ-62 is an antibacterial agent that targets Gram-positive bacteria. It exhibits potent antibacterial activity against Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus faecalis (VRE). HMRZ-62 is particularly valuable for research focused on overcoming antibiotic resistance and developing new therapeutic strategies against resistant bacterial infections.
  42. Anti-Bacterial Agent

    Carpetimycin C is an anti-bacterial agent that exhibits potent activity against both Gram-positive and Gram-negative bacteria, including strains that produce β-lactamase. This compound effectively inhibits β-lactamase activity, making it a valuable tool in research aimed at understanding and combating antibiotic resistance in bacterial infections. Its significant biological effects provide insights into potential therapeutic applications in the field of microbiology.
  43. Anti-Bacterial Agent

    Megovalicin G is an anti-bacterial agent that targets bacterial cells, exhibiting potent activity against Bacillus subtilis, Escherichia coli, and Pseudomonas aeruginosa. This compound is valuable for research applications focused on understanding bacterial resistance mechanisms and developing new antimicrobial therapies. Its broad-spectrum efficacy makes it suitable for studies in microbiology and pharmaceutical development.
  44. Anti-Bacterial Agent

    Nocathiacin I is a potent anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits strong efficacy against methicillin-resistant Staphylococcus aureus (MRSA), penicillin-resistant Streptococcus pneumoniae (PRSP), and multidrug-resistant Enterococcus faecalis (MREF). Nocathiacin I is valuable for research applications focused on combating antibiotic-resistant infections and understanding bacterial resistance mechanisms.
  45. Antibacterial Agent

    LMW peptide is an antimicrobial peptide that targets a broad spectrum of bacterial strains. It exhibits significant antibacterial activity against both Gram-positive bacteria, such as Bacillus subtilis and Listeria monocytogenes, as well as Gram-negative bacteria, including Escherichia coli, Pseudomonas aeruginosa, and Vibrio cholerae. This makes LMW peptide a valuable reagent for research applications aimed at investigating antimicrobial mechanisms and developing new antibacterial therapies.
  46. Anti-Bacterial Agent

    Polymyxin P1 is an anti-bacterial agent derived from Bacillus polymyxa T-39, known for its ability to inhibit Gram-positive bacteria. This compound exhibits significant antibacterial activity, making it a valuable tool for studying bacterial infections and developing antimicrobial therapies. Its unique mechanism of action targets the bacterial cell membrane, disrupting integrity and function. Research applications include evaluating bacterial resistance and testing the efficacy of antibacterial compounds in various experimental models.
  47. Anti-Bacterial Agent

    Cremeomycin is an anti-bacterial agent with potent activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), exhibiting a minimum inhibitory concentration (MIC) of 0.2-0.39 μg/mL. In addition to its antibacterial properties, Cremeomycin demonstrates significant cytotoxicity against various mouse tumor cell lines, such as P388, L1210, IMC, S180, B16, and SS3 in vitro. This compound is valuable in research focused on antibiotic resistance and anticancer therapies.
  48. Antibacterial Agent

    PNU-140457 is an antibacterial agent that targets the 30S ribosomal subunit, effectively inhibiting bacterial protein synthesis. It demonstrates significant antibacterial activity, making it a valuable tool in the study of bacterial infections. This compound is suitable for use in research applications aimed at understanding and combating bacterial growth and resistance mechanisms.
  49. Anti-Bacterial Agent

    Saframycin E is an anti-bacterial agent that primarily targets Gram-positive bacteria, demonstrating effective inhibitory activity against this group. Additionally, it exhibits weak activity against mycobacteria, making it relevant for research in bacterial infections and antibiotic resistance mechanisms. This compound is of interest for studies focused on the development of new antimicrobial therapies.
  50. Anti-Bacterial Agent

    Diperamycin is an anti-bacterial agent primarily targeting Gram-positive bacteria, such as Enterococcus seriolicida and methicillin-resistant Staphylococcus aureus (MRSA), with observed minimum inhibitory concentrations (MICs) ranging from 0.10 to 0.20 μg/mL. Additionally, Diperamycin exhibits potent cytotoxic activity against various cancer cell lines, including L1210, P388, LS-180, KB, HeLaS3, Meth A, and B16-BL6, with IC50 values between 0.009 and 0.098 μg/mL. This compound is valuable for research focusing on bacterial resistance and cancer-related investigations.

Items 4301-4350 of 4946

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