Deoxyenterocin is a bacterial metabolite obtained from Streptomyces, primarily known for its diverse biological activities, including antibiotic, antiviral, and antioxidant effects. It exhibits significant antibacterial activity by inhibiting the growth of pathogens such as S. lutea, S. aureus, K. pneumoniae, and V. percolans at a concentration of 500 μg/mL. Additionally, deoxyenterocin demonstrates antiviral properties, reducing the cytopathic effect of influenza A H1N1 by 60.6% at 50 μg/mL. Moreover, at a concentration of 1 μM, it protects mouse primary cortical neurons from hydrogen peroxide-induced oxidative stress by preserving glutathione levels and mitochondrial membrane potential.
Deoxyenterocin is a bacterial metabolite obtained from Streptomyces, primarily known for its diverse biological activities, including antibiotic, antiviral, and antioxidant effects. It exhibits significant antibacterial activity by inhibiting the growth of pathogens such as S. lutea, S. aureus, K. pneumoniae, and V. percolans at a concentration of 500 μg/mL. Additionally, deoxyenterocin demonstrates antiviral properties, reducing the cytopathic effect of influenza A H1N1 by 60.6% at 50 μg/mL. Moreover, at a concentration of 1 μM, it protects mouse primary cortical neurons from hydrogen peroxide-induced oxidative stress by preserving glutathione levels and mitochondrial membrane potential.
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