Catalog No.
Product Name
Application
Product Information
Citations
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Antibacterial Agent
BAY-Y 3118 hydrochloride is a quinolone antibacterial agent targeting bacterial infections. It demonstrates a broad antibacterial spectrum in vitro, exhibiting strong activity against gram-positive cocci and anaerobes, with moderate efficacy against Enterobacteriaceae and Pseudomonas aeruginosa. This reagent is useful for research applications in infectious diseases, providing a valuable tool for studying antibacterial mechanisms and resistance. -
Antibacterial Agent
(E)-Pinocembrin chalcone is an antibacterial compound derived from Helichrysum trilineatum. It exhibits significant antibacterial activity, making it a valuable reagent for research applications focused on bacterial infections and antimicrobial studies. This compound serves as a potential lead for the development of novel antibacterial agents. -
Anti-Bacterial Agent
Fosfadecin is an anti-bacterial agent that demonstrates moderate antibacterial activity. It is utilized in research to study bacterial infections and evaluate potential therapeutic strategies against bacterial pathogens. Its mechanism of action may provide insights into the development of new antibacterial compounds. -
Antibacterial Agent
Aspersitin is a bioactive metabolite derived from Aspergillus parasiticus, exhibiting potent antibacterial properties. This compound has demonstrated effectiveness against various bacterial strains, making it a valuable research tool in the study of antibacterial mechanisms and the development of new antimicrobial agents. Its utility extends to exploring the biochemical pathways involved in bacterial resistance and susceptibility. -
Antibacterial Agent
Fusaricidin B is an antibacterial agent derived from the lipopeptide biosurfactant of the marine bacterium Paenibacillus polymyxa. This compound exhibits significant inhibitory effects on the formation of biofilms across various bacterial species, including both Gram-positive and Gram-negative bacteria. Additionally, Fusaricidin B demonstrates the ability to disrupt complex and mature biofilms, making it a valuable tool for research into bacterial infections and biofilm-related challenges. -
Anti-Bacterial Agent
Cyathin A3 is an anti-bacterial agent with demonstrated activity against Gram-positive bacteria, Gram-negative bacteria, actinomycetes, and dermatophytes. In addition to its anti-bacterial properties, Cyathin A3 exhibits protective effects in ischemic conditions, showing potential for improving cerebral ischemia in relevant rat models. This compound is valuable for research in microbiology and neurological studies. -
Anti-Bacterial Agent
Chrysospermin D functions as an anti-bacterial agent, exhibiting potent antibacterial activity against various Gram-positive bacteria, including Staphylococcus aureus and Bacillus subtilis, as well as Klebsiella pneumoniae. Additionally, it demonstrates efficacy against specific yeasts such as Ocher echinoderma and Saccharomyces cerevisiae. This compound is useful for research applications focused on bacterial and yeast infections, as well as studies investigating antibacterial mechanisms. -
Anti-Bacterial Agent
Carpetimycin B is a potent anti-bacterial agent known for its robust activity against both Gram-positive and Gram-negative bacteria, including strains that produce β-lactamase. It effectively inhibits β-lactamase activity, making it a valuable tool for research on antibiotic resistance and bacterial infections. This compound is particularly relevant in studies aimed at understanding bacterial mechanisms and developing novel antibacterial therapies. -
Bacterial Metabolite
Reveromycin B is a spiroketal bacterial metabolite that targets epidermal growth factor (EGF) signaling. It effectively inhibits EGF-induced mitogenic activity in Balb/MK cells with an IC50 of 6 μg/mL. Additionally, Reveromycin B displays pH-dependent antifungal properties against Candida albicans, with minimum inhibitory concentrations (MICs) of 15.6 μg/mL at pH 3.0 and greater than 500 μg/mL at pH 7.4, while showing no inhibitory effect on the proliferation of KB and K562 cells. This compound is useful for studying EGF signaling pathways and exploring antifungal mechanisms. -
Anti-Bacterial Agent
11-Deoxydoxorubicin is an anthracycline compound that demonstrates significant antibacterial activity against Gram-positive bacteria as well as notable efficacy against Gram-negative bacteria and tumors. It is utilized in research focused on microbial resistance mechanisms and potential therapeutic interventions for bacterial infections, making it a valuable tool for studying both antibacterial and anticancer properties. -
Anti-Bacterial Agent
Saframycin G is an anti-bacterial agent predominantly effective against Gram-positive bacteria. It exhibits notable cytotoxic activity by inhibiting mouse lymphocyte L-1210 cells, with an ID50 value of 0.03 µM. This compound has potential applications in antibacterial research and the study of lymphocyte proliferation. -
Anti-Bacterial Agent
Heneicomycin is an anti-bacterial agent that exhibits activity against Gram-positive and Gram-negative bacteria, as well as mycoplasma. Its broad-spectrum antimicrobial properties make it valuable for research applications in microbiology and veterinary studies. Additionally, Heneicomycin has been reported to promote animal growth, highlighting its potential in agricultural and animal health research. -
Antibacterial Synergist
Isoreserpiline is an orally active indole alkaloid that functions as an antibacterial synergist by inhibiting bacterial efflux pumps. This compound exhibits both antibacterial and antipsychotic properties and is particularly effective when used in combination with antibiotics. Isoreserpiline has also shown to mitigate amphetamine-induced hyperactivity in animal models, highlighting its potential utility in neuropharmacological research. -
Anti-Bacterial Agent
Amicenomycin B is an anti-bacterial agent with specific activity against Gram-positive bacteria. This compound exhibits potent antimicrobial effects and is valuable for research applications aimed at understanding bacterial resistance mechanisms and developing new therapeutic strategies. Its unique mode of action offers insights into bacterial cell wall synthesis and potential targets for novel antibiotic design. -
Anti-Bacterial Agent
Citreamicin γ is an antibacterial agent effective against Gram-positive aerobic and anaerobic bacteria. This compound exhibits significant antimicrobial activity, making it a valuable tool in studying bacterial infections and resistance mechanisms. Its potential applications extend to research involving antibiotic development and evaluating the efficacy of antibacterial therapies. -
Antibacterial Agent
(1,5-Cyclooctadiene)dimethylplatinum(II) is an antibacterial agent that targets specific bacterial strains. It demonstrates selective activity against certain Gram-positive bacteria, including methicillin-resistant *Staphylococcus aureus* (MRSA) and glycopeptide-intermediate *Staphylococcus aureus* (GISA). Notably, this compound exhibits no hemolytic activity, highlighting its potential for therapeutic applications in treating resistant bacterial infections. -
Anti-Bacterial Agent
Kibdelin A is an anti-bacterial agent that exhibits effective resistance against Gram-positive bacteria. It demonstrates comparable activity to Vancomycin against Staphylococcus aureus, including methicillin-resistant strains. This compound is relevant for research studies focusing on antibiotic resistance and the development of new therapeutic strategies. -
Antibacterial Agent
WCK-1152 is a fluoroquinolone antibacterial agent that targets DNA gyrase and topoisomerase IV. It exhibits significant activity against resistant pathogens, including those with mutations in these enzymes and expressing efflux pumps. This compound is suitable for research focused on infections, particularly respiratory infections caused by resistant strains of pneumococci and staphylococci. -
Antibiotic
Sannamycin E is an aminoglycoside antibiotic derived from Streptomyces sannanensis KC-7038. It exhibits weak antibacterial activity primarily against Gram-positive bacteria. This compound is useful in research applications focused on antibiotic efficacy and resistance mechanisms. -
triazole fungicide
Ipconazole is a triazole fungicide that primarily targets the biosynthesis of ergosterol, a key component of fungal cell membranes. It exhibits potent antifungal activity, making it effective in the control of various fungal pathogens that affect rice seed and other crops. This reagent is valuable for research applications focused on plant protection strategies and the study of fungal resistance mechanisms. -
Anti-bacterial Agent
Tylosin lactate is an anti-bacterial agent effective against spore-forming bacteria. It promotes the growth of Enterococcus and lactobacilli, making it useful in studies related to gastrointestinal health. Tylosin lactate is also employed in research focused on alleviating tylosin-responsive diarrhea in canine models. -
Bacterial Metabolite
Reveromycin D is a bacterial metabolite derived from Streptomyces, known for its ability to inhibit EGF-induced mitogenic activity in Balb/MK cells. This compound exhibits pH-dependent antifungal activity against Candida albicans, with minimum inhibitory concentrations (MICs) of 2 μg/mL at pH 3 and >500 μg/mL at pH 7.4. Additionally, Reveromycin D demonstrates significant antiproliferative effects on KB and K562 cancer cell lines, with IC50 values of 1.6 and 1.3 μg/mL, respectively, making it valuable for research in cell signaling and cancer therapeutics. -
Anti-Bacterial Agent
Manumycin F is an anti-bacterial agent that primarily targets Gram-positive bacteria and exhibits some activity against Escherichia coli. Although its efficacy against other Gram-negative bacteria is limited and it shows no antifungal properties, it is noted for its ability to inhibit RAS Faraday base transfer. In addition, Manumycin F displays weak cytotoxic activity against human colorectal cancer cell lines, specifically HCT-116, with an IC50 value of 15.6 μg/mL, making it a compound of interest in cancer research and antibacterial studies. -
Anti-Bacterial Agent
Cationomycin is an anti-bacterial agent that targets Gram-positive bacteria and mycobacteria. It effectively inhibits their growth while leaving Gram-negative bacteria, yeast, and fungi unaffected. Cationomycin demonstrates potential in veterinary applications, such as preventing coccidiosis in poultry at concentrations of 50-100 ppm. -
Bacterial Inhibitor
AGS1286 sodium, an organosulfur compound, functions as a bacterial inhibitor by targeting enzymatic activities and metabolic pathways influenced by sulfur-containing compounds. This reagent is utilized in research to examine the regulatory effects on bacterial growth and gene expression, making it valuable for studies in microbiology and metabolic regulation. Its unique structural features provide insights into the role of sulfur in microbial dynamics and enzymatic processes. -
Anti-Bacterial Agent
Formadicin A is a potent anti-bacterial agent that exhibits strong activity against various strains of Pseudomonas, Proteobacteria, and alkaline-producing bacilli. Its effectiveness in inhibiting bacterial growth makes it a valuable tool for research applications focused on infectious diseases and antibiotic resistance mechanisms. Further studies may elucidate its potential role in therapeutic development and microbiological investigations. -
Anti-Bacterial Agent
Fujianmycin A is an anti-bacterial agent with demonstrated activity against Bacillus subtilis. This compound functions by inhibiting bacterial growth, making it a valuable tool for research into bacterial infections and the development of new antimicrobial therapies. Its unique mechanism provides insights into bacterial resistance and potential strategies for combatting antibiotic-resistant strains. -
Anti-Bacterial Agent
Lipomycin β is an anti-bacterial agent targeting Gram-positive bacteria. It exhibits potent activity against a variety of Gram-positive pathogens while demonstrating no antifungal effects, including activity against yeasts. This compound is primarily utilized in research focused on bacterial infections and antibiotic development. -
Anti-Bacterial Agent
Cerexin B4 is an anti-bacterial agent specifically targeting Gram-positive bacteria. It exhibits potent activity against a range of pathogenic strains, making it a valuable tool for research in infectious disease and antibiotic resistance. This compound is essential for studies focused on developing new antimicrobial therapies and understanding bacterial mechanisms of resistance. -
Antibacterial Agent
Pefloxacin impurity 1, also known as Pefloxacin impurity B, acts as an antibacterial agent with notable in vitro activity against both Gram-positive and Gram-negative bacteria. This compound serves as a valuable reference standard for research in antibiotic efficacy and bacterial resistance mechanisms, aiding in the development of new antimicrobial agents and understanding of bacterial pathogenesis. -
Antibacterial Agent
Antibacterial Agent 304 is a bactericidal compound that primarily targets the cell wall of bacteria. It exhibits a minimum inhibitory concentration (MIC) of 8 μg/mL against Staphylococcus aureus and Pseudomonas aeruginosa, demonstrating significant antibacterial activity. This reagent is suitable for research applications focused on bacterial infections and the development of sustainable organic photocatalysts. -
Sulfonamide Antibacterial
Sulfamerazine-d4 is a deuterated form of sulfamerazine, a sulfonamide antibacterial agent. It functions by inhibiting bacterial dihydrofolic acid synthesis through competitive inhibition of para-aminobenzoic acid (PABA) binding to dihydropteroate synthase. This compound is valuable for studying sulfonamide mechanisms and understanding bacterial resistance in research applications. -
Anti-bacterial Agent
3,4-Dimethoxytropolone is an anti-bacterial agent with activity against both Gram-positive and Gram-negative bacteria. This compound can be isolated from fermentation broths of Streptoverticillium hadanonense. Its potent antimicrobial properties make it a valuable tool for research applications focused on bacterial resistance and infection mechanisms. -
Anti-Bacterial Agent
20-Deoxysalinomycin is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits significant efficacy against coccidia in poultry, making it a valuable compound for studies on veterinary pharmacology and animal health. Its specific action on these pathogens supports research into effective treatments and prevention strategies in agricultural settings. -
Anti-Bacterial Agent
Cerexin A is an anti-bacterial agent that exhibits strong activity against Gram-positive bacteria. This compound disrupts bacterial cell wall synthesis, leading to cell lysis and death. It holds potential for research applications in developing novel antibacterial therapies and studying mechanisms of resistance in Gram-positive pathogens. -
Antibacterial Metabolite
Renierone is an antibacterial metabolite derived from the marine sponge Reniera sp. It exhibits significant antibacterial activity, making it a valuable tool for research focused on antibiotic development and the exploration of marine-derived compounds. Its unique structure and mechanism of action provide insight into novel therapeutic approaches against bacterial infections. -
Anti-Bacterial Agent
Coriolin C is an anti-bacterial agent known for its activity against Gram-positive bacteria, with limited efficacy against Gram-negative bacteria and yeast, as well as effects on vaginal trichomoniasis. At a concentration of 5 μg/mL, Coriolin C demonstrates a significant inhibitory effect on the growth of Yoshida sarcoma by 61.6%. It is important to note that Coriolin C does not exhibit inhibitory effects on Ehrlich ascites carcinoma in animal models. This compound is valuable for research in microbiology and cancer biology. -
Antibacterial Agent
Leoidin is an inhibitor of the OATP1B1 and OATP1B3 transporters, exhibiting Ki values of 0.08 and 1.84 μM, respectively. This compound effectively blocks sodium fluorescein uptake in CHO cells expressing these transporters. As an antibacterial agent, Leoidin demonstrates activity against both Gram-positive and Gram-negative bacteria by inhibiting phenylalanyl-tRNA synthetase (PheRS) with an IC50 of 42 μM, thereby disrupting bacterial protein synthesis. Leoidin can be isolated from the marine organism L. gangaleoides, making it a valuable tool for microbiological research. -
Antibacterial Agent
Crenatine is an antibacterial agent that primarily targets and disrupts the cell wall synthesis of bacteria. It exhibits greater efficacy against Gram-positive bacteria compared to Gram-negative strains, making it a valuable tool for studies in bacterial infections. Crenatine is ideal for research applications aiming to evaluate antibacterial activity and mechanisms of resistance. -
Anti-Bacterial Agent
Glysperin A is an anti-bacterial agent that targets both Gram-positive and Gram-negative bacteria, including those resistant to aminoglycoside antibiotics. Its broad-spectrum activity makes it a valuable reagent for research applications focused on bacterial resistance mechanisms and the development of new antimicrobial therapies. Glysperin A may facilitate investigations into the efficacy of novel anti-infective strategies and the understanding of bacterial pathogenicity. -
Anti-Bacterial Agent
Monorden E is an anti-bacterial agent that primarily targets cell cycle progression, effectively arresting Jurkat cells in the G1 and G2/M phases. In addition to its cytostatic properties, Monorden E exhibits potent anti-Aspergillus niger activity, making it a valuable tool for research in microbial pathogenesis and cell cycle regulation. -
Antibacterial Activity
Coreoside B, also known as 14-Hydroxycoreoside A, is a naturally occurring flavonoid derived from Coreopsis tinctoria Nutt. It exhibits weak antibacterial activity, making it of interest in microbiological research. Its potential as a lead compound for investigating antibacterial properties can support studies focused on developing new antibacterial agents. -
Anti-Bacterial Agent
Janthinocin A is a potent anti-bacterial agent that targets Gram-positive bacteria, demonstrating strong antimicrobial activity, while also exhibiting moderate efficacy against Gram-negative bacteria. This compound is useful in research aimed at understanding bacterial resistance mechanisms and the development of new antimicrobial therapies. Its unique properties make it a valuable tool for investigating the effects of bacterial infections and potential treatment strategies in the field of microbiology. -
Anti-Bacterial Agent
Saframycin B is an anti-bacterial agent primarily targeting Gram-positive bacteria. It exhibits notable efficacy against various strains, while also demonstrating weak activity against mycobacteria. This compound is useful in research applications aimed at understanding bacterial resistance and developing new antimicrobial strategies. -
Anti-Bacterial Agent
Ekatetrone is an anti-bacterial agent primarily effective against both Gram-positive and Gram-negative bacteria, with notable potency against Mycobacterium tuberculosis. This compound demonstrates significant antibacterial properties, making it a valuable tool for research focused on tuberculosis and other bacterial infections. Its selective activity positions Ekatetrone as a candidate for further investigation in antimicrobial drug development. -
Antibacterial Agent
Antibacterial Agent 310 is a bis-benzimidazole-derived chelating ligand primarily targeting bacterial infections. This compound exhibits significant antibacterial activity and demonstrates the ability to inhibit intracellular viruses. It is suitable for use in antibacterial research and related studies. -
Anti-Bacterial Agent
Pyrronamycin A is an antibacterial agent that exhibits activity against both Gram-positive and Gram-negative bacteria. It has demonstrated efficacy against a range of pathogens, including Staphylococcus aureus, Enterococcus, Escherichia coli, Klebsiella pneumoniae, Proteus, Shigella, and Salmonella. This compound is valuable for research applications focused on antibacterial development and the mechanisms of bacterial resistance. -
Bacterial Inhibitor
VCC234718 is a selective inhibitor of inosine monophosphate dehydrogenase (GuaB2), effectively targeting Mycobacterium tuberculosis (Mtb) to inhibit its growth. With a K value of 100 nM, VCC234718 exhibits non-competitive inhibition involving both IMP and NAD+, demonstrating its ability to disrupt enzymatic function through direct interactions with these metabolites. This compound is valuable for studying mycobacterial infections and developing new treatments for tuberculosis. -
Bacterial Inhibitor
Antitubercular agent-47 (compound 5C) is a potent bacterial inhibitor specifically targeting Mycobacterium tuberculosis. It demonstrates significant efficacy against drug-sensitive (DS), multidrug-resistant (MDR), and extensively drug-resistant (XDR) clinical isolates. This compound is valuable for research applications focused on tuberculosis treatment and drug resistance mechanisms. -
Antibacterial Agent
Austroside A is an antibacterial agent derived from Evodia austrosinensis, targeting bacterial cell functions. It exhibits significant antibacterial activity against antibiotic-resistant strains of Staphylococcus aureus. This compound is particularly valuable for research exploring new therapeutic approaches to combat resistant bacterial infections.
