Peptides

tert-Butyl (2S,4R)-4-hydroxy-2-hydroxymethylpyrrolidine-1-carboxylate is a proline derivative.

N-(tert-Butoxycarbonyl)-S-butylhomocysteine is a cysteine derivative.

(S)-isopropyl 2-(((S)-(perfluorophenoxy)(phenoxy)phosphoryl)amino)propanoate is an alanine derivative.

(S)-2-(Methoxycarbonylamino)-3,3-dimethylbutanoic acid is a leucine derivative.

(R)-2-amino-3-cyclohexylpropanoic acid is an alanine derivative.

Boc-D-Cyclopropylglycine is a small molecule peptide, it can be used for compounds synthesis.

Z-D-Phg-OH (D-Cbz phenylglycine) is a N-blocked amino acids with Kd values of 390 μM and 323 μM for tBuCQN and tBuCQD, respectively.

3-(4-Nitro-phenyl)-L-alanine ethyl ester hydrochloride is an alanine derivative.

(S)-tert-butyl 1-hydroxy-3-phenylpropan-2-ylcarbamate is a phenylalanine derivative.

Glycine ethyl ester monohydrochloride is a Glycine derivative.

Z-DL-Pro-OH (N-Cbz-DL-proline) is a proline derivative, can be used for the synthesis of agents or other compounds.

(S)-2-Methylpyrrolidine-2-carboxylic acid is a proline derivative.

Z-Ala-OSu is an alanine derivative.

Ethyl 2-((3-fluoro-4-(methylcarbamoyl)phenyl)amino)-2-methylpropanoate is an alanine derivative.

Z-D-Chg-OH is a glycine derivative that can be used for amino acid synthesis.

(2R,2'R)-4,4'-Disulfanediylbis(2-aminobutanoic acid) is a cysteine derivative.

Ethyl (tert-Butoxycarbonyl)glycinate is a Glycine derivative.

N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-L-leucine is a leucine derivative.

[(tert-butoxycarbonyl)amino](3-chlorophenyl)acetic acid is a Glycine derivative.

(2S,3S)-2-(Benzyl(methyl)amino)-3-methylpentanoic acid is an isoleucine derivative.

D-Alloisoleucine is an isoleucine derivative.

N-Fmoc-O-benzyl-L-tyrosine is a tyrosine derivative.

(2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3,4-difluorophenyl)propionic acid is a phenylalanine derivative.

S-tert-Leucine N-methylamide is a leucine derivative.

N-BOC-3-Fluoro-D-phenylalanine is a phenylalanine derivative.

L-Alanine, N-[(S)-(4-nitrophenoxy)phenoxyphosphinyl]-, 1-methylethyl ester is an alanine derivative.

4-Methyl-L-leucine is a Glycine derivative.

Ac2-12, an annexin/lipocortin 1 (LC1)-mimetic peptide, inhibit neutrophil extravasation. Ac2-12 has antimigratory action and inhibits recruitment of neutrophils in experimental inflammation models.

Antagonist G is a potent vasopressin antagonist. Antagonist G is also a weak antagonist of GRP and Bradykinin. Antagonist G induces AP-1 transcription and sensitizes cells to chemotherapy.

pp60 c-src (521-533) (phosphorylated) is a peptide corresponding to the pp60c-src carboxy terminal regulatory domain, phosphorylated at Tyr527.

Exendin-3/4 (59-86) is a Exendin-4 peptide derivative.

HAEGTFTSDVS is the first N-terminal 1-11 residues of GLP-1 peptide.

HAEGTFTSD is a 9-residue peptide of human GLP-1 peptide or GLP-1(7-36), amide. GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretionin a glucose-dependant manner

HAEGTFT is the first N-terminal 1-7 residues of GLP-1 peptide.

HAEGT is the first N-terminal 1-5 residues of glucagon like peptide-1 (GLP-1) peptide, and the sequence is His-Ala-Glu-Gly-Thr. HAEGT acts as a competitive substrate for probing prime substrate binding sites of human dipeptidyl peptidase-IV (DPP-IV) 1, in which the N-terminal His-Ala is catalyzed cleavage by DPP-IV. HAEGT can be used in the research of diabetes, obesity.

GR 64349 is a potent and highly selective NK2 receptor peptide antagonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively.

Urocortin, rat (Urocortin (Rattus norvegicus)) is a neuropeptide and a potent endogenous CRFR agonist with Kis of 13 nM, 1.5 nM, and 0.97 nM for human CRF1, rat CRF2α and mouse CRF2β, respectively.

CART(55-102)(rat) is a rat satiety factor with potent appetite-suppressing activity. CART(55-102)(rat) is closely associated with leptin and neuropeptide Y. CART(55-102)(rat) can induces anxiety and stress-related behavior.

[D-Trp34]-Neuropeptide Y is a potent and selective neuropeptide Y (NPY) Y5 receptor agonist. [D-Trp34]-Neuropeptide Y is a significantly less potent agonist at the NPY Y1, Y2, Y4, and y6 receptors. [D-Trp34]-Neuropeptide Y markedly increases food intake in rats.

Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.

Obestatin(human) is a 23-amino acid amidated peptide that regulates appetite and gastrointestinal motility via its interaction with GPR39. Obestatin(human) can be used for weight loss. Obestatin(human) cannot penetrate the cell membrane.

BeKm-1 is a HERG (human ether-a-go-go-related gene) blocking compound. BeKm-1 can be used for the research of heart disease.

Adrenomedullin (AM) (13-52), human is a 40 amino acid peptide, which acts as an endothelium-dependent vasodilator agent.

ACTH (1-13) is a 13-aa peptide, with cytoprotective effects in the model of ethanol induced gastric lesions in rats.

Ceratotoxin A, a 29-residue peptide isolated from the accessory gland secretion fluid, with strong anti-bacterial activity.

MARK Substrate is a MARK substrate peptide.

Gluten exorphin C is an opioid peptide derived from wheat gluten. Its IC50 values are 40 μM and 13.5 μM for μ opioid and δ opioid activities in the GPI and MVD assays, respectively.

Malantide is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts. Malantide is also an efficient substrate for PKC with a Km of 16 μM.

Buforin II, derived from buforin I, a protein isolated from the stomach of the Asian toad Bufo bufo gargarizans, is a potent antimicrobial peptide. Buforin II has antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria.

[Sar9] Substance P is a potent and selective neurokinin (NK)-1 receptor agonist.