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Pelteobagrin

Catalog No.: A27722
Antimicrobial Peptide
Pelteobagrin is an antimicrobial peptide known for its broad-spectrum activity against both Gram-positive and Gram-negative bacteria, as well as fungi, with a minimum inhibitory concentration (MIC) ranging from 2 to 16 μg/mL. Its mechanism of action involves non-competitive disruption of cell wall and cytoplasmic membrane integrity, leading to bactericidal effects. Pelteobagrin holds significant potential for research applications in the study and treatment of infectious diseases.
Pelteobagrin 1314639-41-2 Antimicrobial Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionPelteobagrin is an antimicrobial peptide known for its broad-spectrum activity against both Gram-positive and Gram-negative bacteria, as well as fungi, with a minimum inhibitory concentration (MIC) ranging from 2 to 16 μg/mL. Its mechanism of action involves non-competitive disruption of cell wall and cytoplasmic membrane integrity, leading to bactericidal effects. Pelteobagrin holds significant potential for research applications in the study and treatment of infectious diseases.
Product Information
Catalog NumA27722
FormulaC108H182N26O25
Molecular Weight2244.76
CAS Number1314639-41-2
SequenceGly-Lys-Leu-Asn-Leu-Phe-Leu-Ser-Arg-Leu-Glu-Ile-Leu-Lys-Leu-Phe-Val-Gly-Ala-Leu
Sequence shorteningGKLNLFLSRLEILKLFVGAL
SMILES[C@@H](CC1=CC=CC=C1)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCCN)NC(CN)=O)=O)CC(C)C)=O)CC(N)=O)=O)CC(C)C)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C)=O)=O)[C@@H](C)C)=O)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CO)=O)CC(C)C)=O
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