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Dermaseptin-S2

Catalog No.: A27205
Antimicrobial Peptide
Dermaseptin-S2 is an antimicrobial peptide derived from frog skin, exhibiting potent activity against filamentous fungi. It disrupts cellular membranes, leading to fungal cell death. This peptide is applicable in research related to antifungal mechanisms and the development of novel antimicrobial agents.
Dermaseptin-S2 151896-13-8 Antimicrobial Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDermaseptin-S2 is an antimicrobial peptide derived from frog skin, exhibiting potent activity against filamentous fungi. It disrupts cellular membranes, leading to fungal cell death. This peptide is applicable in research related to antifungal mechanisms and the development of novel antimicrobial agents.
Product Information
Catalog NumA27205
FormulaC155H255N43O43S2
Molecular Weight3473.08
CAS Number151896-13-8
SequenceAla-Leu-Trp-Phe-Thr-Met-Leu-Lys-Lys-Leu-Gly-Thr-Met-Ala-Leu-His-Ala-Gly-Lys-Ala-Ala-Leu-Gly-Ala-Ala-Ala-Asn-Thr-Ile-Ser-Gln-Gly-Thr-Gln
Sequence shorteningALWFTMLKKLGTMALHAGKAALGAAANTISQGTQ
SMILESC([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)[C@@H](C)O)=O)=O)CCC(N)=O)=O)CO)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CC(N)=O)=O)C)=O)C)=O)C)=O)=O)CC(C)C)=O)C)=O)C)=O)CCCCN)=O)=O)C)=O)=O)CC(C)C)=O)C)=O)CCSC)=O)[C@@H](C)O)=O)=O)CC(C)C)=O)CCCCN)=O)CCCCN)=O)CC(C)C)=O)CCSC)=O)[C@@H](C)O)=O)=O)NC([C@@H](NC([C@H](C)N)=O)CC(C)C)=O)C=3C=4C(NC3)=CC=CC4
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