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ToAP2

Catalog No.: A28038
Antimicrobial peptide
ToAP2 is a potent antimicrobial peptide that targets fungal cell membranes. It enhances membrane permeability in Candida albicans, leading to significant alterations in fungal cell morphology. This compound is useful in research focused on fungal pathogenesis, antimicrobial drug development, and the mechanisms of peptide-based antimicrobial activity.
ToAP2 2659258-28-1 Antimicrobial peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionToAP2 is a potent antimicrobial peptide that targets fungal cell membranes. It enhances membrane permeability in Candida albicans, leading to significant alterations in fungal cell morphology. This compound is useful in research focused on fungal pathogenesis, antimicrobial drug development, and the mechanisms of peptide-based antimicrobial activity.
Product Information
Catalog NumA28038
FormulaC144H235N35O32S
Molecular Weight3000.69
CAS Number2659258-28-1
SequencePhe-Phe-Gly-Thr-Leu-Phe-Lys-Leu-Gly-Ser-Lys-Leu-Ile-Pro-Gly-Val-Met-Lys-Leu-Phe-Ser-Lys-Lys-Lys-Glu-Arg
Sequence shorteningFFGTLFKLGSKLIPGVMKLFSKKKER
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC(CNC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CC=CC=C3)N)=O)=O)=O)[C@@H](C)O)=O)CC(C)C)=O)=O)CCCCN)=O)CC(C)C)=O)=O)CO)=O)CCCCN)=O)CC(C)C)=O)[C@H](CC)C)(=O)N4[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=CC=C5)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCC(O)=O)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)CO)=O)=O)CC(C)C)=O)CCCCN)=O)CCSC)=O)[C@@H](C)C)=O)=O)CCC4
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