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WP9QY

Catalog No.: A26223
Bioactive Peptide
WP9QY is a bioactive peptide designed as a TNF-α antagonist. This cyclic peptide effectively mimics the essential recognition loop of tumor necrosis factor on TNF receptor I, thereby inhibiting TNF-receptor interactions. WP9QY serves as a valuable template for developing small molecular inhibitors aimed at mitigating inflammatory bone destruction and systemic bone loss associated with rheumatoid arthritis.
WP9QY 199999-60-5 Bioactive Peptide
Grouped product items
Size Price Stock Qty
500µg
$110.00
In stock
1mg
$185.00
In stock
5mg
$560.00
In stock
10mg
$855.00
In stock
25mg
$1,455.00
In stock
50mg
$1,995.00
In stock
100mg
$2,720.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionWP9QY is a bioactive peptide designed as a TNF-α antagonist. This cyclic peptide effectively mimics the essential recognition loop of tumor necrosis factor on TNF receptor I, thereby inhibiting TNF-receptor interactions. WP9QY serves as a valuable template for developing small molecular inhibitors aimed at mitigating inflammatory bone destruction and systemic bone loss associated with rheumatoid arthritis.
Product Information
Catalog NumA26223
FormulaC58H71N11O15S2
Molecular Weight1226.38
CAS Number199999-60-5
SequenceTyr-Cys-Trp-Ser-Gln-Tyr-Leu-Cys-Tyr (Disulfide bridge:Cys2-Cys8)
Sequence shorteningYCWSQYLCY (Disulfide bridge:Cys2-Cys8)
SMILESCC(C)C[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1
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Peptides