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DOTA-GGNle-CycMSHhex

Catalog No.: A61687
MC1R-targeting peptide
DOTA-GGNle-CycMSHhex is a peptide that targets the melanocortin-1 receptor (MC1R), facilitating radionuclide labeling for imaging applications in melanoma. Its specificity for MC1R makes it an invaluable tool for advancing research in melanoma diagnostics and therapeutic monitoring. This compound is designed to aid in the development of targeted imaging techniques, enhancing the visualization of melanoma in research studies.
DOTA-GGNle-CycMSHhex 1309855-53-5 MC1R-targeting peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDOTA-GGNle-CycMSHhex is a peptide that targets the melanocortin-1 receptor (MC1R), facilitating radionuclide labeling for imaging applications in melanoma. Its specificity for MC1R makes it an invaluable tool for advancing research in melanoma diagnostics and therapeutic monitoring. This compound is designed to aid in the development of targeted imaging techniques, enhancing the visualization of melanoma in research studies.
Product Information
Catalog NumA61687
FormulaC68H99N21O17
Molecular Weight1482.64
CAS Number1309855-53-5
Sequence{DOTA}-Gly-Gly-{Nle}-Asp-His-{dPhe}-Arg-Trp-Lys-NH2 (amide bridge:Asp4-Lys9)
Sequence shortening{DOTA}-GG-{Nle}-DH-{dPhe}-RWK-NH2 (amide bridge:Asp4-Lys9)
SMILESC(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H](NC([C@@H](NC(CNC(CNC(CN6CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC6)=O)=O)=O)CCCC)=O)CC(=O)NCCCC[C@@H](C(N)=O)NC3=O
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