Substance P (6-11)

Catalog No.: A62020
Neuropeptide
Substance P (6-11) is a neuropeptide specifically targeting the NK-1 tachykinin receptor. This C-terminal hexapeptideamide derivative of Substance P demonstrates significant biological activity, including the depolarization of motoneurons and a hypotensive effect. It serves as a valuable tool in research applications focused on neurobiology, pain modulation, and cardiovascular studies.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSubstance P (6-11) is a neuropeptide specifically targeting the NK-1 tachykinin receptor. This C-terminal hexapeptideamide derivative of Substance P demonstrates significant biological activity, including the depolarization of motoneurons and a hypotensive effect. It serves as a valuable tool in research applications focused on neurobiology, pain modulation, and cardiovascular studies.
Product Information
Catalog NumA62020
FormulaC36H52N8O7S
Molecular Weight740.91
CAS Number51165-07-2
Sequence shorteningQFFGLM-NH2
SMILESCSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCC(N)=O)C(N)=O
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