Lys-γ3-MSH(human)

Catalog No.: A61697
Melanocortin Peptide
Lys-γ3-MSH (human) is a melanocortin peptide that targets the melanocortin receptor system, derived from the C-terminal fragment of pro-opiomelanocortin (POMC). It effectively enhances the steroidogenic response of adrenal cells to adrenocorticotrophin (ACTH) and exhibits potent lipolytic activity with an EC50 of 3.56 nM. Lys-γ3-MSH activates hormone-sensitive lipase (HSL) and Perilipin A, making it valuable for research in metabolic regulation and obesity-related studies.
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Size Price Stock Qty
1mg
$355.00
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLys-γ3-MSH (human) is a melanocortin peptide that targets the melanocortin receptor system, derived from the C-terminal fragment of pro-opiomelanocortin (POMC). It effectively enhances the steroidogenic response of adrenal cells to adrenocorticotrophin (ACTH) and exhibits potent lipolytic activity with an EC50 of 3.56 nM. Lys-γ3-MSH activates hormone-sensitive lipase (HSL) and Perilipin A, making it valuable for research in metabolic regulation and obesity-related studies.
Product Information
Catalog NumA61697
FormulaC128H193N45O39S
Molecular Weight3018.25
CAS Number156159-18-1
SequenceLys-Tyr-Val-Met-Gly-His-Phe-Arg-Trp-Asp-Arg-Phe-Gly-Arg-Arg-Asn-Ser-Ser-Ser-Ser-Gly-Ser-Ser-Gly-Ala-Gly-Gln
Sequence shorteningKYVMGHFRWDRFGRRNSSSSGSSGAGQ
SMILESC([C@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC(CNC([C@@H](NC([C@@H](NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](CCCCN)N)=O)=O)C(C)C)=O)CCSC)=O)=O)=O)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=CC=C4)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)C)=O)=O)CO)=O)CO)=O)=O)CO)=O)CO)=O)CO)=O)CO)=O)CC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)C=5C=6C(NC5)=CC=CC6
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