Codactide

Catalog No.: A61674
Peptide
Codactide is a synthetic octadecapeptide that mimics the action of corticotropin, targeting the corticotropin-releasing hormone receptor. This compound exhibits significant neuroendocrine activity that may modulate stress response pathways. Codactide is primarily utilized in research focused on stress-related disorders and the investigation of hypothalamic-pituitary-adrenal (HPA) axis functions.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCodactide is a synthetic octadecapeptide that mimics the action of corticotropin, targeting the corticotropin-releasing hormone receptor. This compound exhibits significant neuroendocrine activity that may modulate stress response pathways. Codactide is primarily utilized in research focused on stress-related disorders and the investigation of hypothalamic-pituitary-adrenal (HPA) axis functions.
Product Information
Catalog NumA61674
FormulaC101H158N30O23S
Molecular Weight2192.59
CAS Number22572-04-9
Sequence{d-Ser}-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Lys-Lys-NH2
Sequence shortening{d-Ser}-YSMEHFRWGKPVGKKKK-NH2
SMILESC([C@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CN=CN1)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=C(O)C=C2)NC([C@@H](CO)N)=O)=O)CO)=O)CCSC)=O)CCC(O)=O)=O)=O)CC3=CC=CC=C3)=O)CCCNC(=N)N)=O)C(NCC(N[C@H](C(=O)N4[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(N)=O)=O)CCCCN)=O)CCCCN)=O)CCCCN)=O)=O)[C@H](C)C)=O)CCC4)CCCCN)=O)=O)C=5C=6C(NC5)=CC=CC6
SynonymsBA-41795
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