Reverse Transcriptase

Inhibitory Selectivity
Catalog No.Inhibitor Name Reverse TranscriptaseOther
A10306Didanosine
**
A12587Dapivirine (TMC120)
***
A10908Tenofovir
A10909Tenofovir Disoproxil Fumarate
A10349Emtricitabine
A11216Entecavir Hydrate
A10039Adefovir Dipivoxil
A10639Nevirapine
A10512Lamivudine
A15428Zidovudine
A11120Abacavir sulfate
A11542Rilpivirine

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.



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Catalog No. Product Name Application Product Information
A10908 SALE

Tenofovir (Viread)

HIV reverse transcriptase inhibitor
Tenofovir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood.
A15428

Zidovudine

NRTI Inhibitor
Zidovudine is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. Azidothymidine decreases CRISPR-mediated homology directed repair (HDR) efficiency.
A14435

Elvucitabine

NRT inhibitor
Elvucitabine is an experimental nucleoside reverse transcriptase inhibitor (NRTI).
A10512 SALE

Lamivudine

-
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).
A12667

Lersivirine (UK-453061)

NNRT inhibitor
Lersivirine (UK-453,061) is a next-generation nonnucleoside reverse transcriptase inhibitor, active against wild-type HIV-1 and several nonnucleoside reverse transcriptase inhibitor-resistant strains.
A12587 SALE

Dapivirine

HIV reverse transcriptase inhibitor
Dapivirine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI)
A10639 SALE

Nevirapine (Viramune)

-
Nevirapine (Viramune) is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase.
A12443

MK-1439

NNRT inhibitor
MK-1439 is a non-nucleoside reverse transcriptase inhibitor
A10306

Didanosine

Reverse transcriptase inhibitor
Didanosine is a reverse transcriptase inhibitor, effective against HIV and used in combination with other antiretroviral drug therapy as part of highly active antiretroviral therapy (HAART).
A10349 SALE

Emtricitabine

NRT inhibitor
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) for the treatment of HIV infection.
A11542 SALE

Rilpivirine (R 278474, TMC 278)

NNRT inhibitor
Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
A10039 SALE

Adefovir dipivoxil

-
Adefovir dipivoxil is an orally-administered nucleotide analog reverse transcriptase inhibitor (ntRTI). It is used for treatment of hepatitis B and herpes simplex virus infection.
A11115 SALE

Abacavir

Transcriptase inhibitor
Abacavir is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS.
A11120 SALE

Abacavir sulfate

Transcriptase inhibitor
Abacavir sulfate is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS.
A10909 SALE

Tenofovir Disoproxil Fumarate

nucleotide reverse transcriptase inhibitor
Tenofovir Disoproxil Fumarate is employed as an anti-HIV agend and a reverse transcriptase inhibitor.
A11216 SALE

Entecavir

Reverse transcriptase inhibitor
Entecavir is a nucleoside analog (more specifically, a guanosine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection.
A15772

GS-7340

NRT inhibitor
GS-7340 is a prodrug of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than TFV disoproxil fumarate.

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