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Adefovir dipivoxil

Catalog No.: A10039

ntRT inhibitor

Adefovir dipivoxil

Adefovir dipivoxil Chemical Structure

CAS NO. 142340-99-6

Adefovir dipivoxil is an orally-administered nucleotide analog reverse transcriptase inhibitor (ntRTI). It is used for treatment of hepatitis B and herpes simplex virus infection.

Availability: In stock

Package Price Qty
50 mg
$40.00
100 mg
$70.00
200 mg
$120.00
10mM * 1mL in DMSO
$63.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Kazumoto Murata, .et al. Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection, Gut, 2018, Feb; 67(2): 362-371 PMID: 27789659

Biological Activity

Adefovir dipivoxil is an orally-administered nucleotide analog reverse transcriptase inhibitor (ntRTI). It is used for treatment of hepatitis B and herpes simplex virus infection.
In vitro DMSO 85 mg/mL (169.5 mM)
Water Insoluble
Ethanol 85 mg/mL (169.5 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10039
Actions Inhibitor
CAS No. 142340-99-6
Formula C20H32N5O8P
M. Wt 501.5
Purity >98%
Synonyms Bis-POM PMEA, Preveon, Hepsera
SMILES CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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