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- Kazumoto Murata, .et al. Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection, Gut, 2018, Feb; 67(2): 362-371 PMID: 27789659
Biological Activity
Adefovir dipivoxil is an orally-administered nucleotide analog reverse transcriptase inhibitor (ntRTI). It is used for treatment of hepatitis B and herpes simplex virus infection.
In vitro | DMSO | 85 mg/mL (169.5 mM) | |
Water | Insoluble | ||
Ethanol | 85 mg/mL (169.5 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.94 mL | 99.7 mL | 199.4 mL |
0.5 mM | 3.99 mL | 19.94 mL | 39.88 mL |
1 mM | 1.99 mL | 9.97 mL | 19.94 mL |
5 mM | 0.4 mL | 1.99 mL | 3.99 mL |
*The above data is based on the productmolecular weight 501.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10039 |
---|---|
Actions | Inhibitor |
CAS No. | 142340-99-6 |
Formula | C20H32N5O8P |
M. Wt | 501.5 |
Purity | >98% |
Synonyms | Bis-POM PMEA, Preveon, Hepsera |
SMILES | CC(C)(C)C(=O)OCOP(=O)(COCCN1C=NC2=C1N=CN=C2N)OCOC(=O)C(C)(C)C |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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