Fig. 1 · Structure
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Zaragozic acid A
Cat. No.
A71406
CAS
142561-96-4
Endogenous Metabolite
Zaragozic acid A is a reversible competitive inhibitor of squalene synthase, acting as an endogenous metabolite. This compound effectively inhibits acute hepatic cholesterol synthesis in mouse models, with an IC50 value of 6 μM. Its application is significant in studies investigating cholesterol metabolism and the regulation of lipid biosynthesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 142561-96-4 |
| Applications | Endogenous Metabolite |
| Formula | C35H46O14 |
| Molecular Weight | 690.73 |
| Synonyms | Squalestatin S1 |
| SMILES | CC[C@@H](C[C@@H](/C=C/C(O[C@@H]1[C@H]([C@]2(O[C@@H]([C@@](C(O)=O)([C@]1(C(O)=O)O2)O)C(O)=O)CCC([C@H]([C@@H](CC3=CC=CC=C3)C)OC(C)=O)=C)O)=O)C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.