Fig. 1 · Structure
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3-(3-Hydroxyphenyl)propionic acid
Cat. No.
A66109
CAS
621-54-5
Endogenous Metabolite
3-(3-Hydroxyphenyl)propionic acid (3HPPA) functions as an endothelium-dependent promoter of nitric oxide (NO) release and an activator of endothelial nitric oxide synthase (eNOS). This compound facilitates vascular smooth muscle relaxation by enhancing NO synthesis in endothelial cells, leading to vasodilation and decreased peripheral vascular resistance. In studies, 3HPPA has shown a dose-dependent ability to lower systolic and diastolic blood pressure in spontaneously hypertensive rats without affecting cardiac contractility or heart rate. Its antihypertensive and vascular protective properties make it a valuable reagent for investigating cardiovascular disease prevention and treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 621-54-5 |
| Applications | Endogenous Metabolite |
| Formula | C9H10O3 |
| Molecular Weight | 166.18 |
| SMILES | O=C(O)CCC1=CC=CC(O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.