Catalog No.
Product Name
Application
Product Information
Citations
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Endogenous Metabolite
ATP ditromethamine is an endogenous metabolite primarily involved in energy storage and metabolism. This compound provides the metabolic energy essential for driving metabolic pumps and acts as a crucial coenzyme in cellular processes. Additionally, ATP ditromethamine functions as an important signaling molecule in immune responses and inflammatory pathways, making it valuable for research in cellular metabolism and immunology. -
Endogenous Metabolite
Secaubryenol is a naturally occurring metabolite classified as a 3,4-secocycloartane triterpene, derived from Coussarea macrophylla. It has demonstrated the absence of cytotoxic effects at concentrations up to 10 μg/mL, suggesting its potential as a safe compound for biological applications. Secaubryenol can be utilized in research exploring plant-derived metabolites and their effects on biological systems. -
Endogenous Metabolite
N-Trifluoroacetyladriamycin (AD-41) is a chemotherapeutic agent that primarily targets tumor cells through its antitumor activity. This compound is notable for its significant accumulation in various tissues, including the small intestine, liver, kidneys, spleen, large intestine, lung, and heart, which correlates with its biological efficacy. As a metabolite of Valrubicin, it plays a crucial role in the inhibition of bladder cancer and is relevant in studies investigating metabolic pathways and antitumor mechanisms associated with its derivatives. -
Endogenous Metabolite
D-Ribose 5-phosphate is an endogenous metabolite and a key intermediate in the oxidative branch of the pentose phosphate pathway (PPP). It plays a crucial role in nucleotide and nucleic acid synthesis, making it essential for cellular processes involving DNA and RNA. This compound is valuable for research focused on metabolic pathways, cellular metabolism, and the biochemistry of nucleotides. -
Fungal Metabolite
Maximiscin is a fungal metabolite known for its ability to induce DNA damage. It exhibits selective cytotoxic activity specifically against a subtype of triple-negative breast cancer, making it a valuable compound for cancer research. Its unique mechanism of action and targeted effects provide insights into potential therapeutic applications for challenging malignancies. -
Fungal Secondary Metabolite
Herbaridine B is a fungal secondary metabolite derived from the endophytic fungus Anteaglonium FL0768, which was isolated from the photosynthetic tissues of Selaginella arenicola. This compound exhibits notable biological activity, making it a valuable tool for research in mycology and phytopathology. Its potential applications include studying fungal metabolomics and interactions between endophytes and their host plants. -
Endogenous Metabolite
Protein-arginine deiminase is an enzyme that catalyzes the conversion of peptidyl-arginine to peptidyl-citrulline through hydrolysis. This post-translational modification plays a significant role in various biological processes, including gene regulation, cellular signaling, and the modulation of immune responses. It is particularly relevant in the study of inflammatory diseases and autoimmune conditions, making it a valuable reagent for research applications in biochemistry and molecular biology. -
Endogenous Metabolite
Eprozinol hydrochloride is an endogenous metabolite with antibronchoconstrictor activity. This compound is primarily utilized in the study of bronchospasm and related respiratory disorders. Its mechanism of action makes it a valuable tool for researchers investigating bronchial hyperreactivity and potential therapeutic approaches for asthma and other obstructive pulmonary conditions. -
Endogenous Metabolite
Heptanoyl-L-carnitine chloride is an acylcarnitine that acts as an endogenous metabolite. This compound is known to induce exercise-related changes in the human metabolome, particularly in plasma and skeletal muscle tissues. Its biological activity makes it a valuable reagent for research into metabolic processes and the effects of physical activity on metabolism. -
Endogenous Metabolite
1,3-Distearoyl-2-palmitoyl glycerol is an endogenous metabolite primarily involved in the composition of triglycerides. This compound has been extensively analyzed using various chromatographic techniques, contributing to the characterization of bovine milk fat and identifying a total of 120 distinct triglycerides. Its study offers valuable insights into lipid metabolism and dairy science research applications. -
Endogenous Metabolite
Deutarserine is a deuterium-modified analogue of the endogenous metabolite D-serine. It acts as a co-agonist at the NMDA receptor, playing a crucial role in neurotransmission and neuromodulation. This compound is primarily utilized in research focused on schizophrenia and other neuropsychiatric disorders, aiming to elucidate the pathways and therapeutic potential associated with D-serine in adult populations. -
Endogenous Metabolite
Oxogestone phenpropionate is an endogenous metabolite with a primary mechanism of action as a progesterone receptor modulator. This compound is utilized in research to investigate hormone regulation and the physiological effects of progesterone in various biological systems. Its applications extend to studies related to reproductive biology and endocrine function. -
Endogenous metabolites
13,14-dihydro-15(R)-Prostaglandin E1 serves as an analog of 13,14-dihydro-Prostaglandin E1, featuring a hydroxyl group at C-15 in the R configuration. This compound is primarily engaged in research applications focused on endogenous metabolites. Its unique structural characteristics allow for investigations into prostaglandin signaling pathways and their physiological implications. -
Endogenous Metabolite
Guanoxyfen nitrate is a targeted inhibitor of the serine protease TMPRSS2, which is essential for the entry of coronaviruses into host cells. This compound exhibits significant biological activity by inhibiting TMPRSS2-mediated proteolytic processes, thereby diminishing viral infectivity. Additionally, guanoxyfen nitrate effectively suppresses vasoconstrictor responses to sympathetic nerve stimulation, making it a valuable reagent for research in virology and cardiovascular physiology. -
Fungal Metabolite
Beauverolide Ka is a cyclodepsipeptide metabolite derived from the Beauveria bassiana fungus. This compound enhances glucose uptake in cultured rat L6 myoblasts at a concentration of 50 μM and demonstrates protective effects on HEI-OC1 cells at 10 μM. Additionally, Beauverolide Ka exhibits dose-dependent biological activity in both L6 myoblasts and myotubes, making it a valuable reagent for research in cellular metabolism and neuroprotection. -
Endogenous Metabolites
NAD Synthetase is an enzyme that catalyzes the final step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). This enzyme demonstrates differing Km values for its substrates, with values of 200 μM for NAD, 11 μM for ATP, and 0.65 μM for ammonia in Escherichia coli, and 170 μM for NAD, 190 μM for ATP, and 64 μM for ammonia in yeast. NAD Synthetase is applicable for enzymatic assays targeting ATP, ammonia, urea, or creatinine, and is suitable for enzymatic cycling methods. Furthermore, it holds promise for advancing research in metabolic diseases, cancer, aging, and neurodegenerative disorders. -
Fungal Metabolite
Banksialactone A is a fungal metabolite derived from Aspergillus banksianus. This compound exhibits significant antifungal activity, making it a valuable tool for investigating fungal biology and potential therapeutic applications. Research involving Banksialactone A can contribute to understanding fungal metabolism and the development of antifungal agents. -
Endogenous Metabolite
sn-Glycerol 3-phosphate biscyclohexylammonium salt is a key endogenous metabolite involved in glycolysis and lipid metabolism. It is produced through the NADH-dependent activity of cytosolic sn-Glycerol 3-phosphate dehydrogenase, converting dihydroxyacetone phosphate into sn-Glycerol 3-phosphate. This compound is essential for glyceroneogenesis, contributing significantly to lipid synthesis and energy production, making it valuable for research in metabolic pathways and lipid-related studies. -
Endogenous Metabolite
AZD-3289 is a potent β-secretase 1 (BACE1) inhibitor, aimed at modulating the production of β-amyloid protein. Its primary biological activity involves reducing β-amyloid accumulation in the brain, which may contribute to slowing the progression of Alzheimer's disease. AZD-3289 is primarily utilized in research focused on neurodegenerative disorders, with potential applications in enhancing cognitive function by targeting the underlying mechanisms of Alzheimer's pathology. -
Endogenous Metabolite
Flucythrinate is a synthetic pyrethroid that exerts its effects primarily through binding to the vitamin D nuclear receptor (VDR), exhibiting a binding affinity score of -11.0 kcal/mol. This compound possesses endocrine suppressive properties and has been suggested as a multi-target ligand capable of interacting with various proteins implicated in breast cancer. Flucythrinate's efficacy in binding site prediction and affinity estimation has been validated through rigorous screening methods, making it a valuable reagent for research in cancer biology and endocrine disruption studies. -
Endogenous Metabolite
GSK-1562590 is a high-affinity antagonist of the uropeptide-II receptor, demonstrating notable selectivity. This compound exhibits significant antagonistic activity across various biological assays and maintains prolonged receptor binding. GSK-1562590 effectively inhibits human urinary peptide-II-induced aortic contraction in rat models, with effects persisting for a minimum of 24 hours. Its properties make it a valuable tool for investigating the role of uropeptide-II in cardiovascular physiology and related metabolic research. -
Leukotriene
Leukotriene C4 methyl ester is a metabolic derivative of leukotriene C4, primarily functioning as a potent mediator in inflammatory responses. It exhibits significant biological activity in promoting vascular permeability and bronchoconstriction, making it relevant for studying a variety of inflammatory conditions. This compound is particularly useful for research focused on psoriasis and other related dermatological disorders, facilitating the exploration of leukotriene signaling pathways. -
Endogenous Metabolite
1-Myristoyl-2-linoleoyl-3-palmitoyl-rac-glycerol is a triglyceride characterized by its unique structural composition and distribution in biological matrices. This endogenous metabolite has been identified in human milk, infant formulas, various mammalian milks, and certain vegetable oils, providing insights into its potential role in nutrition and metabolism. Research applications include studying lipid metabolism, evaluating dietary sources of essential fats, and investigating the health benefits associated with triglycerides in human development. -
Fungal Metabolite
Butyrolactone II is a fungal metabolite derived from Aspergillus flavipes, known for its activity as a biosynthetic precursor. It exhibits significant biological activity, particularly in the regulation of secondary metabolites and has been identified for its role in modulating fungal growth. This compound is primarily utilized in research applications studying fungal biology, metabolic pathways, and the development of antifungal strategies. -
Endogenous Metabolite
Linoleoyl-L-carnitine chloride is an endogenous metabolite that functions as a long-chain acylcarnitine. It has been shown to exhibit significant biological activity, particularly in lipid metabolism and energy homeostasis. Research applications include studies on metabolic dysregulation and the pharmacological effects of compounds like isoniazid, which can elevate hepatic levels of linoleoyl-L-carnitine in murine models at high doses. -
Endogenous Metabolite
Conicasterol is a 4-mercaptosteroid known for its significant cytotoxic activity against cancer cells. It exhibits an IC50 value of 6.23 μg/mL in human breast adenocarcinoma cell line (MCF-7), indicating strong potential for antitumor applications. This compound may serve as a valuable bioactive lead molecule in cancer research and therapeutic development. -
Endogenous Metabolite
1-Stearoyl-2-palmitoyl-3-oleoyl-rac-glycerol is an endogenous metabolite primarily associated with triglyceride composition. It plays a vital role in lipid metabolism and has been utilized in research to analyze the triglyceride profiles within bovine milk fat. The compound has been characterized through various chromatographic techniques, contributing to the identification of a diverse array of triglycerides in biological samples. -
Endogenous Metabolite
Demethyl PL265 is a selective dual ENKephalinase inhibitor (DENKi) targeting the enzymatic breakdown of endogenous enkephalins. This compound demonstrates significant potential in alleviating pain through the modulation of endogenous opioid signaling pathways. Its ability to enhance enkephalin levels may provide valuable insights into pain management strategies and the study of opioid-related mechanisms in neurobiology. -
Endogenous Metabolite
NPE-caged-proton functions as a caged proton donor that releases protons upon exposure to UV light. This reagent enhances the activity of the fusion protein GP64 under mildly acidic conditions, facilitating the interaction of enveloped viruses with liposome membranes comprised of acidic phospholipids at pH levels ranging from 4.0 to 5.5. Utilized in viral membrane fusion studies, NPE-caged-proton serves as an essential tool for investigating viral behavior and interactions in diverse chemical and biochemical environments. -
Endogenous Metabolite
Glucoiberin potassium is an endogenous metabolite known for its role in modulating metabolic pathways. This compound exhibits biological activity that can influence glucose metabolism and insulin sensitivity. Research applications include studies on diabetes, metabolic disorders, and the evaluation of cellular response to dietary components. -
Endogenous Metabolite
4-Chloro-N,N-diisopropylbenzamide is an amide with significant relevance as a substrate for cytochrome P450 enzymes in vivo and for acetylcholinesterase in vitro. This compound plays a crucial role in metabolic studies, enabling the investigation of enzyme kinetics and substrate specificity. Its application extends to research focused on drug metabolism and neuropharmacology. -
Endogenous metabolite
13,14-EDT is an endogenous metabolite derived from oxylipids and adrenal acid, produced via the cytochrome P450 (CYP) enzymatic pathway. This compound is of significant interest in the study of lipid metabolism and related biological processes. It serves as a valuable tool for investigating the roles of CYP enzymes in metabolic pathways and their implications in various physiological conditions. -
Endogenous Metabolite
Methyl β-D-Galactopyranoside is an endogenous metabolite primarily involved in carbohydrate metabolism. This compound serves as a galactose donor and is utilized in various biological assays to study glycosylation processes and carbohydrate-binding proteins. Its role in cell signaling and metabolism makes it valuable for research applications focusing on glycobiology and cellular interactions. -
Endogenous Metabolite
Cedefingol is an endogenous metabolite that acts as an α-glucosidase inhibitor. This compound demonstrates antitumor properties and exhibits diverse bioactivities influenced by the fermentation time of dark tea samples. Additionally, cedefingol displays antioxidant activity, as evidenced by its effectiveness in the DPPH assay. Research applications include studies on metabolic pathways, enzymatic processes, and potential therapeutic effects in cancer research. -
Endogenous Metabolite
SSR180711 is a potent and subtype-selective agonist of the α7 nicotinic acetylcholine receptor. This compound demonstrates significant activity in the context of Alzheimer's disease and schizophrenia, making it valuable for research into cognitive function. Additionally, SSR180711 can be utilized to investigate intracerebral hemorrhage subtypes related to cerebral small vessel disease and is applicable in electrophysiological and behavioral studies focused on cerebrovascular lesions and their impacts. -
Endogenous Metabolite
Thromboxane B2 ethanolamide (TXB2-EA) is an endogenous metabolite derived from the hydrolysis of thromboxane A2 ethanolamide. It serves as a critical regulator in various physiological processes, including platelet function and vascular tone. TXB2-EA is useful in research focused on cardiovascular health and thrombotic disorders, providing insights into the roles of thromboxane signaling in health and disease. -
Endogenous Metabolite
Xanthosine-5'-monophosphate is an endogenous metabolite involved in nucleoside metabolism. It plays a role in the purine nucleotide cycle and has implications in various cellular processes. Xanthosine-5'-monophosphate is utilized in research applications related to metabolic pathways, enzyme activity studies, and the investigation of nucleotide signaling mechanisms. -
Endogenous Metabolite
(R)-3-Hydroxyisobutyric acid sodium is an endogenous metabolite associated with the metabolic disorder 3-hydroxyisobutyric aciduria, which is characterized by increased urinary levels of this compound. This reagent is instrumental in metabolic studies and can be used in research investigating metabolic pathways and associated disorders. Its utility in diagnosing metabolic abnormalities makes it an important tool in clinical and biochemical research. -
Endogenous Metabolite
9(S)-HODE cholesteryl ester is an endogenous metabolite associated with atherosclerotic lesions. Its structure contains an oxidized fatty acid component, likely derived from either enzymatic lipoxygenation or lipid peroxidation. This compound serves as a valuable standard for the analysis of chiral HODE cholesteryl esters, facilitating research into lipid metabolism and cardiovascular disease. -
Endogenous Metabolite
Rovicurt is a mixture of permethrin and tetramethrin that targets endogenous metabolites, demonstrating significant effects on reproductive physiology. It stimulates biological adaptation mechanisms, leading to an increase in the diameter of seminiferous tubules and the proliferation of Sertoli cells. Additionally, Rovicurt enhances the fertilizing ability of sperm, making it a valuable reagent for research in reproductive biology and environmental toxicology studies. -
Endogenous Metabolite
(Rac)-Terreic acid is a natural product that primarily inhibits mitotic kinase 8, a key regulator in cell division. With its capability to modulate cell signaling pathways, (Rac)-Terreic acid serves as a valuable bioactive molecule for studying the mechanisms of cell proliferation and survival. This compound is relevant for research applications focused on cellular dynamics and cancer biology. -
Endogenous Metabolite
Carbonate Ionophore VII is a selective transporter for carbonate ions, facilitating their movement across lipid membranes. This compound is primarily employed in the development of ion-selective electrodes, enabling precise measurement of carbonate concentrations in various biological and environmental samples. Its application is crucial for studies involving cellular metabolism and physiological processes where carbonate ions play a significant role. -
Endogenous Metabolite
Diadenosine pentaphosphate pentaammonium is an endogenous vasoactive purine dinucleotide that serves as a crucial metabolite in cellular signaling. It is primarily found in platelet secretory vesicles and plays a significant role in the regulation of vascular tone and thrombocyte function. This compound is useful in research related to purinergic signaling, platelet activation, and neurobiology, providing insights into cellular communication mechanisms and potential therapeutic targets. -
Endogenous Metabolite
1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol is a triglyceride enriched with fatty acid esters of hydroxy fatty acids (FAHFAs) that serves as a significant intracellular reservoir of FAHFAs. This compound plays a crucial role in modulating cellular levels of FAHFAs, thereby influencing lipid metabolism and signaling pathways. Research applications include investigating triglyceride and FAHFAs metabolism, as well as understanding their implications in metabolic diseases and cellular homeostasis. -
Endogenous Metabolite
(±)20-HDHA is a racemic mixture and an autoxidation product of Docosahexaenoic acid (DHA). It is produced via peroxidation processes in human platelets and rat brain homogenate. This compound serves as an endogenous metabolite, making it relevant for research into lipid metabolism and the oxidative stress response in various biological systems. -
Endogenous Metabolite
D-Glyceric acid is an endogenous metabolite that plays a significant role in metabolic pathways. It is particularly valuable in research related to primary hyperoxaluria type I and glutaric acidemia type 2. Its presence in urine makes it a key biomarker for studying these metabolic disorders and aids in understanding the biochemical mechanisms underlying these conditions. -
Endogenous Metabolite
9α,11β-Prostaglandin F2α is an endogenous metabolite that plays a significant role in various physiological processes. It is primarily studied for its involvement in respiratory conditions, particularly asthma, where it may influence bronchial tone and inflammation. This compound offers vital insights into the mechanisms of asthma and related disorders, facilitating research into potential therapeutic strategies. -
Endogenous Metabolite
Phosphorylcholine chloride calcium salt tetrahydrate is an endogenous metabolite that plays a crucial role in cellular signaling and membrane integrity. This compound is involved in various biological processes, including cell proliferation and differentiation. It is utilized in research applications focusing on cell biology, neurobiology, and immunology, serving as a key component in studies related to lipid metabolism and membrane dynamics. -
Endogenous Metabolite
4-Methyl-1-phenyl-2-pentanone is an endogenous metabolite with potential implications in metabolic studies. This compound is involved in various biochemical pathways and may play a role in the regulation of neurochemical processes. Its application spans research areas such as pharmacology, biochemistry, and toxicology, where it can be utilized to investigate metabolic disorders and neuroactive substances. -
Endogenous Metabolite
Erythronic acid is an endogenous metabolite derived from carbohydrates, playing a crucial role in metabolic pathways. It is instrumental in investigating metabolic diseases, particularly in understanding hyperuricemia and its association with mitochondrial dysfunction, especially in cases of transaldolase deficiency. This compound serves as a valuable tool for researchers exploring the biochemical mechanisms underlying these conditions.
