Moracin M is a phenolic compound derived from Mori Cortex that acts as a potent inhibitor of phosphodiesterase-4 (PDE4), exhibiting IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. This compound demonstrates significant anti-inflammatory activity, making it a valuable tool for research in inflammation and related signaling pathways. Its potential applications include studying the role of PDE inhibition in various disease models.
Moracin M is a phenolic compound derived from Mori Cortex that acts as a potent inhibitor of phosphodiesterase-4 (PDE4), exhibiting IC50 values of 2.9, 4.5, >40, and >100 μM for PDE4D2, PDE4B2, PDE5A1, and PDE9A2, respectively. This compound demonstrates significant anti-inflammatory activity, making it a valuable tool for research in inflammation and related signaling pathways. Its potential applications include studying the role of PDE inhibition in various disease models.
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