Fig. 1 · Structure
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Meglutol
Cat. No.
A39357
CAS
503-49-1
Endogenous Metabolite
Meglutol is an endogenous metabolite that functions as a lipid-lowering agent by inhibiting HMG-CoA reductase, a key enzyme in cholesterol biosynthesis. It effectively reduces levels of cholesterol, triglycerides, serum β-lipoprotein, and phospholipids. Additionally, Meglutol is noted for inducing significant lipid oxidative damage in brain tissue, making it a valuable tool for research in cardiovascular and metabolic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 503-49-1 |
| Applications | Endogenous Metabolite |
| Formula | C6H10O5 |
| Molecular Weight | 162.14 |
| Synonyms | Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid |
| SMILES | O=C(O)CC(C)(O)CC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.