Endogenous Metabolite

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  1. oncometabolite

    Fumaric acid is a fundamental unit of nucleic acids.. It is a oncometabolite or an endogenous, cancer causing metabolite. High levels of this organic acid can be found in tumors or biofluids surrounding tumors. Its oncogenic action appears to due to its ability to inhibit prolyl hydroxylase-containing enzymes.
  2. anticancer agent

    Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways.
  3. Stachyose is a prebiotic, a non-reducing tetrasaccharide in the rafnose family of oligosaccharides with few side efects.
  4. neurotropic agent

    Pyritinol, also known as pyrithioxine, is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.
  5. Purinergic P2 receptor antagonist

    Pyridoxyl phosphate is a purinergic P2 receptor antagonist potentially for the treatment of tardive dyskinesia
  6. L-Azetidine-2-carboxylic acid is an endogenous metabolite.

  7. Sodium D-Pantothenate is a vitamin that performs an important role in the oxidation of fats and carbohydrates and certain amino acids. It is also a precursor in the biosynthesis of coenzyme A.
  8. Longifolene is the common (or trivial) chemical name of a naturally occurring, oily liquid hydrocarbon found primarily in the high-boiling fraction of certain pine resins. The name is derived from that of a pine species from which the compound was isolated, Pinus longifolia (obsolete name for Pinus roxburghii Sarg.) Chemically, longifolene is a tricyclic sesquiterpene.
  9. Cortisone is a naturally occurring glucocorticoid. It has been used in replacement therapy for adrenal insufficiency and as an anti-inflammatory agent. Cortisone itself is inactive. It is converted in the liver to the active metabolite HYDROCORTISONE.
  10. Butylated hydroxytoluene is di-tert-butyl PHENOL with antioxidant properties.
  11. antioxidant

    Tartaric acid is an endogenous metabolite.
  12. L-Lactic acid is used as a substrate for lactic acid dehydrogenase and lactate oxidase.
  13. Hydroxyacetic acid is a dermatologic agent. It has also been used as a plant-tissue based biosensor and chemiluminescence flow sensor.
  14. antimicrobial pesticide

    Octanoic acid is an antimicrobial pesticide used as a food contact surface sanitizer.
  15. 2'-Deoxyguanosine (Deoxyguanosine) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.
  16. ADP
    Adenosine diphosphate is an adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
  17. Uridine 5'-monophosphate (5'-?Uridylic acid), a monophosphate form of UTP, can be acquired either from a de novo pathway or degradation products of nucleotides and nucleic acids in vivo and is a major nucleotide analogue in mammalian milk.
  18. Undecanoic acid (Undecanoate) is a monocarboxylic acid with antimycotic property, which inhibits the production of exocellular keratinase, lipase and the biosynthesis of several phospholipids in T. rubrum.
  19. Oxtriphylline is a cough medicine derived from xanthine that acts as a bronchodilator to open up airways in the lung. Chemically, it is a salt of choline and theophylline. It classifies as an expectorant.
  20. L-(-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions.
  21. neuroprotective agent

    Citicoline Sodium is a neuroprotective agent. It acts by enhancing cellular communication, stimulating the synthesis of SAMe, and increasing glucose metabolism.
  22. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
  23. non-essential amino acid

    DL-Glutamine (Glutamin, 2-amino-4-carbamoylbutanoic acid) is a non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes.
  24. cancer chemopreventive agent

    L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells.
  25. L-Asparagine is a non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue.
  26. Creatine is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine.
  27. Alanine is a non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.
  28. neurotransmitter

    Aspartic acid is one of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
  29. Methionine is a sulfur-containing essential L-amino acid that is important in many body functions.
  30. Cysteine is a thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
  31. Eicosapentaenoic Acid (EPA; Timnodonic acid) is an omega-3 fatty acid.
  32. Citicoline is a neuroprotective agent. It acts by enhancing cellular communication, stimulating the synthesis of SAMe, and increasing glucose metabolism.
  33. neurotropic agent

    Pyrithioxine HCl is a neurotropic agent which reduces permeability of blood-brain barrier to phosphate. It has no vitamin B6 activity.
  34. Undecylenic acid is a fatty acid with a terminal double bond. Undecylenic acid is an active ingredient in medications for skin infections, and to relieve itching, burning, and irritation associated with skin problems.
  35. Flavin Adenine Dinucleotide Disodium is a redox cofactor, more specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism.
  36. Tricaprilin, also known as Glyceryl trioctanoate, is a triglyceride drug candidate.
  37. Sodium deoxycholate is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
  38. Dichlorisone acetate is a Glucocorticoid.
  39. Bcl-2 Family activator

    (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299.
  40. (R)-Pantetheine is the biosynthetic precursor to CoA. (R)-Pantetheine and its corresponding disulfide pantethine, play a key role in metabolism as a building block of coenzyme A (CoA).
  41. Choline bitartrate is a form of the nutrient choline which is found in foods.
  42. Choline chloride is a quaternary ammonium salt used as an additive for animal feed.
  43. Deoxycorticosterone acetate (DOCA) is a corticosteroid.
  44. excitatory transmitter/agonist

    L-Glutamic acid monosodium salt acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). (S)-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
  45. Impulsin (AM 3112) is an active endogenous compound which can used for preventing virus infection of the respiratory tract.
  46. COX-2 inhibitor

    Salicylic acid (2-Hydroxybenzoic acid) is a beta hydroxy acid that occurs as a natural compound in plants which is an inhibitor of ethylene biosynthesis and cyclooxygenase activity.
  47. Sucralose is an activator of taste receptor, type 1, member 2 (T1R2) and taste receptor type 1, member 3 (T1R3).
  48. Vitamin D2 (Ergocalciferol) is a form of vitamin D, used as a vitamin D supplement.
  49. 3-methoxy Tyramine (HCl) is a natural metabolite of dopamine, produced by catechol-O-methyltransferase (COMT).
  50. Antioxidants

    Glutathione oxidized, or GSSG, results from glutathione undergoing oxidation. It plays a crucial role in neutralizing reactive oxygen species, a process that concurrently generates GSSG. This oxidized form of glutathione is pivotal in studies concerning sickle cells and erythrocytes, where it's utilized for research purposes.

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