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Endogenous Metabolite
Cis-5-Tetradecenoic acid is an endogenous metabolite that plays a significant role in metabolic processes. It is useful for investigating Long Chain 3 Hydroxyacyl CoA Dehydrogenase Deficiency and its associated biochemical pathways. This compound serves as a valuable tool in research aimed at understanding lipid metabolism and related disorders. -
Endogenous Metabolite
(S,S)-Dehydroemetine is an endogenous metabolite with antispasmodic properties, primarily targeting smooth muscle contraction. This compound exhibits inhibitory activity, making it a valuable reagent for research into disorders associated with aberrant smooth muscle activity, such as gastrointestinal and respiratory conditions. Its potential applications extend to the study of therapeutic strategies aimed at modulating smooth muscle function. -
Endogenous Metabolite
O-Acetyl-L-serine hydrochloride functions as an endogenous metabolite involved in various biochemical pathways. This compound plays a role in the synthesis of cysteine and is crucial for cellular metabolism. Its applications include research in metabolic disorders and studies related to amino acid metabolism. -
Endogenous Metabolite
1-Benzyl-3-phenylthiourea is an endogenous metabolite that acts as a sensor material for nerve agents and their simulants. This compound exhibits biosensor activity, enhancing the sensitivity and detection capabilities of various sensor systems. Its reactive characteristics closely mimic those of nerve agents, making it a reliable candidate for improving detection methods in chemical research applications. -
Endogenous Metabolite
(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate is an endogenous metabolite known for its role in cellular signaling pathways. It serves as a lipid mediator, influencing various biological processes such as cell proliferation and differentiation. This compound has applications in research related to metabolism, cell biology, and the study of lipid-related diseases. -
Endogenous Metabolite
Sodium creatine phosphate dibasic tetrahydrate is an endogenous metabolite that serves as a key substrate for creatine kinase. This compound plays a critical role in the resynthesis of ATP during skeletal muscle contraction, facilitating energy production in muscle tissues. It is widely used in biochemical research to study muscle metabolism and energy dynamics. -
Fungal Metabolite
D-Iditol is a fungal metabolite characterized as a sugar alcohol that accumulates in cases of galactokinase deficiency. It is of interest for its potential antitumor activity, making it a valuable compound for research related to cancer biology and metabolic disorders. Studies may explore its effects on cellular processes and its potential therapeutic applications. -
Endogenous Metabolite
Potassium 2-hydroxy-2-methylsuccinate is an endogenous metabolite that plays a critical role in metabolic pathways. It is known for its involvement in energy production and regulation of physiological processes. This compound can be utilized in research applications focusing on metabolic studies, biomarker identification, and the investigation of metabolic disorders. -
Endogenous Metabolite
Oxalic acid diammonium monohydrate is a strong dicarboxylic acid that serves as an endogenous metabolite, playing a significant role in various biological processes. Its applications include use as an analytical reagent and a general reducing agent in chemical research. This compound is particularly valuable in studies related to plant metabolism and the identification of organic compounds in biological samples. -
Endogenous Metabolite
L-(−)-Glyceraldehyde is an endogenous metabolite that plays a pivotal role as an intermediate in carbohydrate metabolism. It is involved in various biochemical pathways, contributing to glycolysis and other metabolic processes. This compound is essential for studying metabolic regulation and enzyme activity in research applications focused on energy metabolism and carbohydrate biosynthesis. -
Endogenous Metabolite
Indole-3-butyric acid potassium acts as a plant growth auxin, promoting the rooting of herbs and woody ornamental plants. This compound enhances fruit set and is a key precursor to indole-3-acetic acid (IAA) via peroxisomal β-oxidation. Its applications extend to agricultural research and horticultural studies, emphasizing its importance in plant developmental processes. -
Endogenous Metabolite
3-Aminocoumarin, an endogenous metabolite, functions as a key intermediate in the synthesis of metal complexes. This compound exhibits significant biological activity and is utilized in various research applications, including studies on coordination chemistry and the development of fluorescent probes. Its versatile structure facilitates exploration in medicinal chemistry and materials science. -
Endogenous Metabolite
Rac-1-Linoleoyl-3-linolenoyl-propanetriol is an endogenous metabolite that acts as a diacylglycerol. This compound features linoleic acid at the sn-1 position and α-linolenic acid at the sn-3 position, and is typically derived from olive oil through lipase-catalyzed glycerolysis using immobilized lipase B from C. antarctica. It is of significant interest in research related to lipid metabolism, signaling pathways, and potential health benefits associated with dietary fatty acids. -
Endogenous Metabolite
5-Aminoimidazole ribonucleotide (AIR) is an endogenous metabolite that serves as a key intermediate in purine biosynthesis. AIR undergoes further enzymatic modifications, ultimately leading to the production of inosine monophosphate (IMP), a precursor for the purine bases adenine and guanine. This compound is essential for research in metabolic pathways, nucleotide biosynthesis, and cellular energy regulation. -
Endogenous Metabolite
1,2-Dioctanoyl-3-decanoyl-rac-glycerol is a triglyceride that serves as an endogenous metabolite identified in microalgae biomass through ion mobility-mass spectrometry. This compound is essential for characterizing microalgae biomass, enabling researchers to investigate its distribution across various microalgae species and its interactions with other metabolites. Its applications extend to the field of biofuel production, making it a valuable tool for understanding lipid composition and optimizing biomass yields. -
Endogenous Metabolite
Rel-(2R,3S)-2,3-Dihydroxysuccinic acid hydrate is an endogenous metabolite that serves as a key intermediate in various metabolic processes. This compound exhibits significant biological activity, influencing metabolic pathways associated with energy production and cellular signaling. It is utilized in research applications focused on metabolic disorders and the biochemical mechanisms underlying cellular metabolism. -
Endogenous Metabolites
Taurodehydrocholic acid is a bile acid that acts as an endogenous metabolite, primarily influencing cholesterol metabolism. It is known to significantly enhance the expression of Abcg5 while reducing the expression of Abca8, thereby regulating biliary cholesterol secretion. This compound serves as a valuable tool for investigating mechanisms underlying cholesterol homeostasis and related metabolic disorders. -
Endogenous Metabolite
1,2-Dioleoyl-3-linoleoyl-rac-glycerol (OOL) is a triacylglycerol targeting endogenous lipid metabolism. It comprises oleic acid at the sn-1 and sn-2 positions and linoleic acid at the sn-3 position. OOL is present in various seed and vegetable oils, such as pumpkin seed, olive, and sesame oils, making it relevant for studies related to lipid profiles and metabolic pathways in nutritional and physiological research. -
Endogenous Metabolite
[(3R)-3-Hydroxydodecanoyl]-L-carnitine is an endogenous metabolite that primarily targets mitochondrial metabolism. This compound plays a critical role in the regulation of fatty acid oxidation and energy production. It is utilized in research applications investigating metabolic disorders, mitochondrial dysfunction, and the mechanisms of energy homeostasis. -
Endogenous Metabolite
7β,25-Dihydroxycholesterol is an endogenous metabolite that functions as a chemoattractant for immune cells expressing EBI2. This compound plays a significant role in modulating immune responses and has implications in studies related to inflammation and autoimmune diseases. Its ability to guide immune cell migration makes it a valuable tool for research exploring immune system dynamics and therapeutic interventions. -
Endogenous Metabolite
(±)-Equol 4'-sulfate sodium is a sodium salt of the endogenous metabolite derived from the isoflavonoid phytoestrogen (±)-Equol. It plays a crucial role in estrogenic activity and serves as a significant biomarker in hormone-related research. This compound is of interest for studies investigating the effects of phytoestrogens on health, as well as their potential implications in various biological pathways. -
Endogenous Metabolite
Quercetin 5-O-β-D-glucopyranoside is a flavonoid that acts as an endogenous metabolite. It plays a significant role in the metabolic processes of insects, as evidenced by its presence in the cocoon shell of Bombyx mori. This compound exhibits antioxidant properties and is utilized in various research applications, including studies on insect metabolism and the exploration of flavonoid biosynthesis in plants. -
Endogenous Metabolite
Urobilin hydrochloride is an endogenous metabolite derived from the breakdown of hemoglobin. This compound is primarily excreted through urine and feces in various mammals, serving as an important biomarker for assessing human waste pollution. Its detection and quantification can be utilized in environmental monitoring and studies related to metabolic disorders. -
Endogenous Metabolite
L-(+)-Fructose, 95% is the L-isomer of D-Fructose, functioning as an endogenous metabolite with a crucial role in glycolysis and gluconeogenesis. This reagent is essential for studies related to photosynthesis and carbohydrate storage in plant biology, offering insights into metabolic pathways. Additionally, L-(+)-Fructose, 95% can be utilized to explore the activity of fructokinase and other enzymes involved in fructose metabolism, aiding in the understanding of carbohydrate dynamics in various biological systems. -
Endogenous Metabolite
Tetrachlorvinphos is an organophosphorus compound that primarily acts as a cholinesterase inhibitor. This metabolite is commonly utilized in agricultural settings for pest control due to its effectiveness against a variety of insects. With low toxicity to mammals, tetrachlorvinphos serves as a useful tool for studying pesticide interactions and their effects on non-target organisms. -
Endogenous Metabolite
(S)-3-Hydroxypropane-1,2-diyl dioctanoate is an endogenous metabolite and a cell-permeable analog of the PKC-activating second messenger diacylglycerol (DAG). It plays a crucial role in cellular signaling processes and is known to induce the acrosome reaction in human sperm. This compound is valuable for studying mechanisms of sperm activation and related reproductive biology research. -
Endogenous Metabolite
C17 Sphingomyelin (d18:1/17:0) is a synthetic derivative of sphingomyelin, primarily functioning as an internal standard for the quantification of sphingomyelin levels in biological samples. It serves as a valuable tool in lipidomics research, facilitating the analysis of sphingolipid metabolism and its implications in various biological processes. This compound is essential for precisely measuring sphingomyelin concentrations and understanding its role in cellular function and disease mechanisms. -
Endogenous Metabolite
Isocolumbin is a diterpenoid metabolite derived from Jateorhiza palmate Miers, commonly known as Colombo root. It exhibits various biological activities, including anti-inflammatory and antioxidant effects. Isocolumbin serves as a valuable tool for research applications in pharmacology and natural product studies, potentially aiding in the discovery of therapeutic agents. -
Endogenous Metabolite
2-Keto-3-deoxy-6-phosphogluconate is an endogenous metabolite that plays a crucial role as an intermediate in the Entner-Doudoroff pathway. This compound is significant for understanding the degradation processes of sugar acids and sugar polymers in both human and plant pathogens. Its formation is catalyzed by KDPG aldolase, making it vital for metabolic research and studies focused on microbial metabolism. -
Endogenous Metabolite
L-2-Phosphoglyceric acid is an endogenous metabolite that plays a crucial role in cellular metabolism. It serves as an intermediate in the phosphoglycerate pathway, influencing biochemical reactions related to glycolysis and gluconeogenesis. This compound is of interest in research applications focusing on metabolic studies and investigations into energy production and regulation within cells. -
Endogenous Metabolite
CE(16:1(9Z)), also known as cholesteryl palmitoleate, is a cholesterol ester that serves as an endogenous metabolite. It is notably elevated in the plasma of ApoE-/- mice subjected to cigarette smoke exposure and in pediatric patients with biliary atresia. This compound is commonly used as a reference standard for the identification and study of cholesterol esters in human meibomian gland secretions, contributing to investigations in lipid metabolism and related disorders. -
Endogenous Metabolite
Ganglioside GD1b Disodium Salt (Bovine Brain) is an acidic glycosphingolipid that acts as an endogenous metabolite and is characterized by two sialic acid residues connected to an internal galactose unit. This compound is known to facilitate the formation of lipid microdomains through its interaction with cholesterol, thereby influencing intracellular and intercellular signaling. Elevated levels of Ganglioside GD1b have been associated with aging and higher grades of pilocytic astrocytoma, as well as being present in various gliomas, including glioblastomas, primitive neuroectodermal tumors, and anaplastic astrocytomas, highlighting its potential relevance in cancer research. -
Endogenous Metabolite
Dehydrochenodeoxycholic acid is an endogenous metabolite and a ketone bile acid that plays a role in various physiological processes. Its primary mechanism involves the modulation of bile acid synthesis and metabolism, influencing lipid digestion and absorption. This compound is used in research applications focused on gastrointestinal health, lipid metabolism, and potential therapeutic implications related to metabolic disorders and liver function. -
Endogenous Metabolite
UCM-05194 is a selective agonist of the LPA1 receptor, primarily targeting neuropathic pain pathways. This compound exhibits potent activity by triggering LPA1-mediated cellular effects, leading to receptor internalization and functional inactivation in primary sensory neurons. UCM-05194 effectively reduces pain perception in in vivo models, making it a valuable tool for investigating mechanisms underlying progressive systemic diseases and potential therapeutic applications in pain management. -
Endogenous Metabolite
2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol is a triglyceride functioning as an endogenous metabolite. This compound plays a critical role in lipid metabolism and cellular signaling pathways. Its biological activity makes it valuable for research applications related to metabolic disorders and the study of lipid profiles in various physiological and pathological states. -
Endogenous Metabolite
Bisphenol M is an endogenous metabolite recognized for its antioxidant properties. It is utilized in various industrial applications, particularly in the production of plastics and resins, where it serves as a stabilizer and preservative. Additionally, Bisphenol M is employed in certain food packaging materials to enhance product durability and safety, making it relevant for research in material science and food safety studies. -
Endogenous Metabolite
Pantoic acid is an endogenous metabolite involved in the biosynthesis of D-pantothenic acid, a crucial component of coenzyme A. This compound plays a significant role in various metabolic pathways, including fatty acid synthesis and energy metabolism. Pantoic acid is useful for research focused on metabolic processes and the regulation of coenzyme A levels in biological systems. -
Endogenous metabolites
Indole-3-lactate-O-β-D-glucopyranoside is an endogenous metabolite that functions as a plant growth regulator. It plays a critical role in mediating plant growth and development through hormone signaling pathways. This compound is useful in research applications focused on plant biology, including studies on growth regulation and metabolic profiling. -
Endogenous Metabolite
NCX 1000 is a liver-specific nitric oxide (NO) donor compound derived from ursodeoxycholic acid (UDCA). This endogenous metabolite facilitates the release of nitric oxide, which plays a crucial role in various physiological processes, particularly in liver function. NCX 1000 is primarily used in research applications focusing on hepatic biology, NO signaling pathways, and the investigation of liver-related diseases. -
Endogenous Metabolite
(±)-γ-Tocopherol is an endogenous metabolite that plays a critical role in various biological processes. It exhibits potent antioxidant properties and has been shown to influence cell signaling pathways that may be relevant in the context of cancer research. This compound is particularly useful for investigating its potential role in the pathogenesis of prostate and endometrial cancers. -
Endogenous Metabolite
aPKC-IN-2 is a selective inhibitor of atypical protein kinase C (aPKC), targeting its activity to modulate cellular signaling pathways. This compound effectively reduces vascular endothelial permeability in both in vitro and in vivo models, demonstrating significant actions against vascular endothelial growth factor (VEGF) and tumor necrosis factor (TNF). aPKC-IN-2 interferes with NFκB-mediated gene transcription, highlighting its role in regulating inflammatory responses. The EC50 value of aPKC-IN-2 is in the low nanomolar range, laying the groundwork for advancing small molecule aPKC inhibitors in therapeutic research. -
Endogenous Metabolite
3β,7α-Dihydroxycholest-5-enoic acid is an endogenous metabolite involved in cholesterol metabolism. This compound plays a role in bile acid synthesis and may influence lipid homeostasis. It is useful in research applications focused on lipid biology, metabolic disorders, and cholesterol-related diseases. -
Endogenous Metabolite
MAGL-IN-3 is a selective inhibitor of monoacylglycerol lipase (MAGL) with an IC50 of 34.1 nM. This compound effectively reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release in Neuro2a cells at a concentration of 1 μM. Additionally, administration of MAGL-IN-3 at a dosage of 10 mg/kg significantly elevates levels of 2-arachidonoyl glycerol in mouse brain, making it a valuable tool for studying endocannabinoid signaling and neurobiological processes. -
Endogenous Metabolite
1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol that features linoleic acid side chains at the sn-1 and sn-2 positions, targeting various metabolic pathways. It plays a significant role as a component of phosphatidic acid in rat liver mitochondria and spinach chloroplast membranes. Additionally, this compound is identified as a potential biomarker for predicting preeclampsia in early pregnancy, making it relevant for studies on pregnancy-related conditions and lipid metabolism. -
Endogenous Metabolite
Acetonitrile-15N is a stable isotope-labeled compound primarily utilized as an endogenous metabolite in metabolic research. With applications in biolabeling experiments, it facilitates the tracking of metabolic pathways and elucidation of chemical reaction mechanisms within various organisms. Additionally, Acetonitrile-15N is instrumental in environmental science, aiding in the study of pollutant migration and transformation processes. -
Endogenous Metabolite
Biotin sodium, an endogenous metabolite, functions as a critical coenzyme for five carboxylases in humans. It plays a vital role in various metabolic processes, including fatty acid synthesis, isoleucine and valine metabolism, and gluconeogenesis. This water-soluble B vitamin is essential for cell growth and the metabolism of fats and amino acids, making it valuable in biochemical research and applications related to metabolism and nutrition. -
Endogenous Metabolite
Methyl cyclohexanecarboxylate acts as an endogenous metabolite in various biological systems. This compound plays a role in metabolic pathways and can be utilized in research focusing on metabolomics and biochemical analysis. Its study may provide insights into metabolic regulation and physiological functions. -
Endogenous Metabolite
Jalapinolic acid (11-Hydroxyhexadecanoic acid; 11-Hydroxypalmitic acid) is an endogenous metabolite with potential roles in lipid metabolism and cellular signaling. This hydroxyhexadecanoic acid has been shown to influence various biological processes, making it valuable for research into metabolic disorders and the study of fatty acid derivatives. Its unique biochemical properties facilitate investigations into its effects on cellular functions and metabolic pathways. -
Endogenous Metabolite
Estriol 16α-(β-D-glucuronide) is an endogenous metabolite primarily involved in estrogen metabolism and is prevalent in urine. It serves as a valuable biomarker in pregnancy-related research, aiding in the assessment of fetal development and maternal health. This compound is essential for studies investigating hormonal changes during gestation and may provide insights into various pregnancy complications. -
Endogenous Metabolite
(±)7(8)-EpDPA is an epoxide derivative of docosahexaenoic acid (DHA) formed through CYP450-mediated metabolism. This compound serves as an endogenous metabolite and is involved in various cellular processes, including inflammation and cellular signaling. It is utilized in research to study the biochemical pathways of omega-3 fatty acids and their effects on physiological functions.

