Catalog No.
Product Name
Application
Product Information
Citations
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Purine Nucleoside Analog
3’-Deoxy-3’-fluoroinosine is a purine nucleoside analogue that interferes with DNA synthesis and induces apoptosis, demonstrating significant antitumor activity. This compound is primarily used in research related to indolent lymphoid malignancies, offering insights into therapeutic strategies targeting cancerous tissues. Its unique mechanism of action makes it a valuable tool for studying purine metabolism and apoptotic pathways in cancer biology. -
Adenosine Analog
N6-Methyladenosine N1-oxide is an adenosine analogue primarily known for its role as a smooth muscle vasodilator. This compound exhibits significant biological activity, including the potential to inhibit cancer progression, making it valuable in cancer research and cardiovascular studies. Its unique properties allow for exploration in various therapeutic applications within the realms of oncology and vascular biology. -
Nucleoside Analogue
1-(2-C-β-Methyl-β-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a nucleoside analogue featuring a nitropyridine core structure. This compound exhibits potential antiviral activity and is valuable in research exploring nucleoside metabolism and the development of antiviral therapies. Its unique structural modifications may serve as a tool for studying nucleotide synthesis and its implications in cellular processes. -
Purine Nucleoside Analog
1-β-D-Ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine is a purine nucleoside analog that exhibits significant antitumor properties. It primarily exerts its biological activity through the inhibition of DNA synthesis and the induction of apoptosis, making it valuable in the study of indolent lymphoid malignancies. This compound is useful for research applications focused on cancer therapeutics and the mechanisms of cancer cell proliferation. -
Purine Nucleoside Analog
9-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)-6-methyl-9H-purine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis in cancer cells. It serves as a valuable tool in cancer research for exploring mechanisms of action and developing new therapeutic strategies. -
Purine Nucleoside Analog
2',3'-Di-O-acetyl-8-benzyloxy-3'-deoxy-3'-fluoroguanosine is a purine nucleoside analog primarily known for its antitumor properties. This compound exhibits significant biological activity by inhibiting DNA synthesis and inducing apoptosis in cancer cells, making it a valuable tool in cancer research. It is particularly relevant for studies targeting indolent lymphoid malignancies, where purine nucleoside analogs can offer therapeutic potential. -
Purine Nucleoside Analog
2′-Deoxy-2′-fluoro-3-deaza-arabinouridine is a purine nucleoside analog that exerts significant antitumor effects by inhibiting DNA synthesis and inducing apoptosis. This compound is particularly beneficial for research involving indolent lymphoid malignancies, providing insights into potential therapeutic strategies for cancer treatment. Its unique structure enhances its biological activity, making it a valuable tool in anticancer research applications. -
Purine Nucleoside Analog
N3-Methyl-5-methyluridine is a purine nucleoside analog recognized for its potent antitumor activity against indolent lymphoid malignancies. This compound functions primarily by inhibiting DNA synthesis and inducing apoptosis, thereby regulating cell proliferation and promoting cancer cell death. Research applications include exploring mechanisms of cancer treatment and evaluating therapeutic strategies in hematological malignancies. -
Purine Nucleoside Analog
5-Bromo-2'-deoxy-2'-fluoro-β-D-arabinouridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA synthesis and induction of apoptosis, making it a valuable tool for cancer research. This compound is suitable for studies focused on understanding the molecular pathways of cancer and evaluating therapeutic interventions. -
Purine Nucleoside Analog
2'-Deoxy-2'-fluoro-6-S-methyl-6-thio-arabino-inosine is a purine nucleoside analog that exhibits significant antitumor activity against indolent lymphoid malignancies. Its mechanism of action primarily involves the inhibition of DNA synthesis and the induction of apoptosis. This compound is valuable for research focused on cancer therapeutics and understanding the molecular pathways involved in tumor growth. -
Purine Nucleoside Analog
3’-Azido-3’-deoxycytidine is a purine nucleoside analog that exhibits notable antitumor activity, primarily targeting indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a versatile click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it valuable in diverse chemical biology applications. -
Purine Nucleoside Analog
5-O-TBDPS-1,2-di-O-isopropylidene-3-keto-alpha-D-xylofuranoside is a purine nucleoside analog that serves as an effective tool in the study of cancer biology. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as the inhibition of DNA synthesis and induction of apoptosis. Its applications in research extend to the development of novel therapeutic strategies targeting specific malignancies. -
Purine Nucleoside Analog
N,N-Dimethyl-2′-O-methyladenosine is a purine nucleoside analogue that exhibits significant antitumor activity. Its primary mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in research focused on indolent lymphoid malignancies. This compound is utilized in studies aimed at understanding cancer biology and exploring therapeutic strategies for lymphoproliferative disorders. -
Nucleoside Metabolite
4-Oxo-4,5-dihydroimidazole-5-acetic acid is a nucleoside metabolite that plays a crucial role in nucleic acid metabolism. This compound influences the degradation and synthesis of nucleotides, making it valuable for studies focused on cellular proliferation and genetic regulation. Its applications extend to research in enzymatic activity involving nucleoside triphosphate pools and their effects on cellular processes. -
Thymidine Analog
2',3',5'-Tri-O-benzoyl-5-hydroxy methyluridine is a thymidine analog known for its ability to integrate into replicated DNA. This compound exhibits insertional activity, making it useful for cell labeling and monitoring DNA synthesis in various experimental settings. Its application is valuable in studies focused on nucleic acid metabolism and cellular proliferation. -
Purine Nucleoside Analog
9-(2'-O-Acetyl-5'-O-benzoyl-3'-deoxy-beta-D-ribofuranosyl)-6-chloropurine is a purine nucleoside analog that exerts broad antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research and therapeutic studies. This compound may also be useful in exploring the biochemical pathways associated with nucleoside metabolism and cancer cell proliferation. -
Purine Nucleoside Analog
5’-Deoxy-5’-N,N-dimethylamino thymidine is a purine nucleoside analog that primarily targets DNA synthesis. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, by inducing apoptosis and inhibiting cellular proliferation. This compound serves as a valuable tool for research in cancer biology and therapeutic development. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-N6,N6-dimethyladenosine is a purine nucleoside analogue that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. As a click chemistry reagent, it features an azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with reactive partners like DBCO or BCN. This versatility makes it a valuable tool for various research applications in chemical biology and medicinal chemistry. -
Purine Nucleoside Analog
6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog that primarily targets nucleic acid synthesis. Its biological activity includes broad antitumor properties, particularly effective against indolent lymphoid malignancies. Mechanistically, it functions through the inhibition of DNA synthesis and the induction of apoptotic pathways, making it a valuable tool for cancer research and therapeutic development. -
Purine Nucleoside Analog
N1-Methoxymethyl pseudouridine is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. This compound functions by inhibiting DNA synthesis and inducing apoptosis, contributing to its effectiveness in cancer research. N1-Methoxymethyl pseudouridine serves as a valuable tool for investigating mechanisms of cancer cell proliferation and therapeutic responses. -
Nucleoside Metabolite
CMP-2-Aminoethylphosphonate is a nucleoside metabolite that serves as a phosphonate analog of nucleotide structures. It is involved in various biochemical pathways and can be utilized in research applications focusing on nucleotide metabolism and cellular signaling. This compound may also provide insights into the role of nucleoside metabolites in cellular processes and their potential therapeutic applications. -
Purine Nucleoside Analog
2-Chloro-2′-deoxy-N,N-dimethyladenosine is a purine nucleoside analog that primarily targets purine metabolism. This compound exhibits substantial antitumor activity, particularly against indolent lymphoid malignancies, by mechanisms including inhibition of DNA synthesis and induction of apoptosis. It serves as an important tool for research in cancer biology and therapeutic development. -
Purine Nucleoside Analog
1-Beta-D-arabinofuranosyl-5-iodouracil is a purine nucleoside analog known for its broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research in cancer biology and therapeutic development. This compound is particularly useful in studies exploring the molecular pathways involved in tumor growth and resistance. -
Adenosine Analog
2'-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine is an adenosine analog that primarily targets adenosine receptors. This compound exhibits significant smooth muscle vasodilatory activity and has potential applications in inhibiting cancer progression. Its mechanism of action makes it a valuable tool for researchers studying cardiovascular function and cancer therapeutics. -
Nucleoside Metabolite
(Z)-But-1-ene-1,2,4-tricarboxylate, also known as cis-Homoaconitate, is a nucleoside metabolite that plays a crucial role in metabolic pathways. It has been implicated in various biological processes and can be utilized in research applications focused on nucleoside metabolism and related biochemical pathways. Its biochemical activities make it a valuable tool for investigating metabolic disorders and enzyme activity in cellular studies. -
Purine Nucleoside Analog
8-Benzyloxy-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exhibits potent antitumor activity. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it useful in the study of indolent lymphoid malignancies. This compound is valuable for research applications in cancer biology and therapeutic development targeting nucleoside metabolism. -
Purine Nucleoside Analog
2-Amino-7-cyclopropyl methyl-7,8-dihydro-8-oxo-9-(beta-D-xylofuranosyl)purine is a purine nucleoside analog that targets a variety of biological pathways. This compound exhibits broad antitumor activity, making it particularly relevant in the study of indolent lymphoid malignancies. Its mechanisms of action include inhibition of DNA synthesis and the induction of apoptosis, underscoring its potential as a therapeutic agent in cancer research. -
Histidine Metabolite
D-Erythro-1-(imidazol-4-yl)glycerol 3-phosphate is an important metabolite in the histidine metabolism pathway. This compound has potential utility as a biomarker for epilepsy, providing insights into its biochemical underpinnings. It serves as a valuable tool for researchers studying metabolic processes related to histidine and their implications in neurological disorders. -
Purine Nucleoside Analog
2’,3’,5’-Tri-O-benzoyl-2’-β-C-methyl-3-deazauridine is a purine nucleoside analog that exerts its biological activity by inhibiting DNA synthesis and inducing apoptosis. This compound demonstrates significant antitumor efficacy, particularly against indolent lymphoid malignancies. Research applications include investigating the mechanisms of action of nucleoside analogs in cancer therapy. -
Purine Nucleoside Analog
2-Deoxy-2’-deoxy-5’-(4,4’-dimethoxytrityl)uridine is a purine nucleoside analog primarily targeting DNA synthesis. This compound exhibits significant antitumor activity, particularly in the treatment of indolent lymphoid malignancies. Its mechanisms of action involve the inhibition of DNA replication and the induction of apoptosis in cancer cells, making it a valuable reagent for cancer research and therapeutic development. -
Nucleoside Metabolite
6β-Hydroxy-17β-estradiol is a nucleoside metabolite that serves as an important intermediate in estrogen metabolism. This compound exhibits key biological activities related to the modulation of estrogen receptor signaling pathways. It is valuable for research applications focused on understanding hormonal regulation, endocrine disorders, and estrogen-related diseases. -
Purine Nucleoside Analog
2',3',5'-Tri-O-benzoyl-6-azauridine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis. This compound is useful in cancer research focused on understanding nucleoside metabolism and developing new therapeutic approaches for lymphoid cancers. -
PNP Inhibitor
BCX-5 is a selective inhibitor of purine nucleoside phosphorylase (PNP), offering an inhibitory potency with a Ki value of 0.08 μM. This compound is known to impede cell proliferation and modulate mixed lymphocyte reactions by elevating levels of inosine and guanosine in plasma. BCX-5 is valuable for research applications in immunology, providing insights into purine metabolism and lymphocyte function. -
Purine Nucleoside Analog
2′,3′-Anhydroadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis in cancer cells. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Nucleotide Sugar
UDP-6-azido-6-Deoxy-D-Glc is a nucleotide sugar that serves as a valuable tool for biochemical research. This compound can be utilized for the selective labeling of 5-hydroxymethylcytosine (5-hmC) in genomic DNA, facilitating studies related to epigenetics and gene regulation. Its unique azide functionality allows for click chemistry applications, enabling further exploration of nucleotide sugar biosynthesis and modification processes. -
Purine Nucleoside Analog
3’-Azido-3’-deoxy-5-methyl-beta-L-cytidine is a purine nucleoside analog known for its antitumor activity, particularly in indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. Additionally, this compound serves as a click chemistry reagent, featuring an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. -
Thymidine Analog
5-[3-[(Trifluoroacetyl)amino]propyl]uridine is a thymidine analog that exhibits insertional activity towards replicated DNA. This compound is valuable for labeling cells and monitoring DNA synthesis in various research applications. Its structural similarity to thymidine allows for effective incorporation into DNA, facilitating studies in cellular proliferation and genetic analysis. -
Purine Nucleoside Analog
N6-Benzoyl-2’-chloro-2’-deoxyadenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its primary mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool in cancer research. This compound is commonly utilized in studies aimed at understanding the molecular pathways of cancer development and therapeutic response. -
Thymidine Analog
5-(Azidomethyl)-2’-O-(2-methoxyethyl)uridine is a thymidine analog exhibiting insertional activity towards replicated DNA. This compound is utilized for cellular labeling and tracking of DNA synthesis. It contains an azide group, making it a valuable click chemistry reagent capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-bearing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, offering versatility in chemical biology applications. -
DNA Methylation Inhibitor
Dihydro-5-azacytidine is a DNA methylation inhibitor that is incorporated into the DNA structure, disrupting normal methylation processes. This compound exhibits antitumor activity, making it a valuable tool for cancer research. Its properties are relevant for studies focused on epigenetic regulation and the development of therapeutic strategies targeting DNA methylation. -
Purine Nucleoside Analog
2-Chloro-N6-methyladenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms primarily involve the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for research applications in cancer biology and therapeutic development. This compound is suitable for studies investigating the molecular pathways involved in tumor progression and treatment response. -
Uridine Analog
4'-Cyanouridine is a uridine analog that serves as a valuable tool for exploring the biological functions of uridine in various physiological contexts. Its potential antiepileptic properties make it a candidate for studying anticonvulsant and anxiolytic activities. Additionally, 4'-Cyanouridine may contribute to the development of novel antihypertensive therapies, facilitating research into its therapeutic applications. -
Purine Nucleoside Analog
5'-Deoxy-5'-iodoguanosine is a purine nucleoside analog that functions by inhibiting DNA synthesis and promoting apoptosis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action make it a valuable tool in cancer research, providing insights into therapeutic strategies for nucleoside-based treatments. -
Nucleoside Metabolite
2-Oxo-(4R)-hydroxy-5-aminovaleric acid is a nucleoside metabolite with critical implications in cellular metabolism. It plays a significant role in the regulation of amino acid pathways and may influence nucleic acid synthesis. This compound is utilized in research to study metabolic pathways and their effects on cellular functions. -
Purine Nucleoside Analog
5-(Trifluoromethyl)uridine is a purine nucleoside analogue that exhibits significant anti-tumor activity, particularly against indolent lymphoid malignancies. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis. This compound is widely utilized in cancer research to elucidate therapeutic strategies and evaluate potential treatment pathways. -
Purine Nucleoside Analog
1,N6-Etheno-ara-adenosine is a purine nucleoside analog that exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its mechanism of action involves the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for cancer research. This compound is primarily utilized in studies focused on the development of novel therapeutic strategies for hematological cancers. -
Uridine Analog
N3-Allyluridine is a uridine analog that targets various biological pathways associated with nucleoside metabolism. It has demonstrated potential in exploring anticonvulsant and anxiolytic activities, positioning it as a useful tool for research in epilepsy and anxiety disorders. Additionally, N3-Allyluridine can aid in the development of novel antihypertensive agents, advancing the understanding of cardiovascular pharmacology. -
Purine Nucleoside Analog
1-β-D-Arabinofuranosyl-5-bromo-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog that exhibits significant antitumor activity. Its mechanisms of action include the inhibition of DNA synthesis and the induction of apoptosis, making it a valuable tool for targeting indolent lymphoid malignancies. This compound is instrumental in cancer research and therapeutic studies focused on nucleoside analogs. -
Purine Nucleoside Analog
N6-Dimethylamino methylidene-2’-deoxyisoguanosine is a purine nucleoside analog that targets key pathways in cellular metabolism. It exhibits significant antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms such as DNA synthesis inhibition and the induction of apoptosis. This compound is valuable for research applications focused on cancer biology and therapeutic development. -
Purine Nucleoside Analog
1-Amino-8-benzyloxy-9-(β-D-xylofuranosyl)guanine is a purine nucleoside analog that exerts its effects by targeting DNA synthesis pathways. This compound demonstrates notable antitumor activity, particularly against indolent lymphoid malignancies, through mechanisms including the inhibition of DNA replication and the induction of apoptosis. It is a valuable tool for researchers investigating cancer therapies and the pharmacological properties of nucleoside analogs.
