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DNA-GAG

Ricin toxin A-chain (RTA) Substrate

DNA-GAG is a specialized substrate for Ricin toxin A-chain (RTA), functioning as a slow-reacting compound. It facilitates the depurination of a specific adenylate within the GAGA stem-loop structure of eukaryotic 28S RNA, highlighting RTA's mechanism of action. This substrate is valuable in studying the biochemical pathways and toxicological effects associated with ricin exposure, aiding research in molecular biology and therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	54230-76-1
Applications	Ricin toxin A-chain (RTA) Substrate
Formula	C₃₀H₃₇N₁₅O₁₅P₂
Molecular Weight	909.65
SMILES	O=C1C(N=CN2[C@H]3C[C@H](OP(OC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)C[C@@H]4OP(OC[C@H]7O[C@@H](N(C=N8)C9=C8C(NC(N)=N9)=O)C[C@@H]7O)(O)=O)(O)=O)[C@@H](CO)O3)=C2N=C(N)N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.