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3’-β-Amino-2’,3’-dideoxy-5’-O-methoxy trityluridine

Purine Nucleoside Analog

3'-β-Amino-2',3'-dideoxy-5'-O-methoxy trityluridine is a purine nucleoside analog that effectively inhibits DNA synthesis. This compound exhibits significant antitumor activity, particularly against indolent lymphoid malignancies. Its pharmacological mechanisms include the induction of apoptosis and disruption of cellular proliferation, making it valuable for research in cancer biology and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2072145-31-2
Applications	Purine Nucleoside Analog
Formula	C₂₉H₂₉N₃O₅
Molecular Weight	499.56
SMILES	N[C@@H]1C[C@H](N(C(N2)=O)C=CC2=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.