2′-O-2-Propyn-1-ylguanosine is a guanosine analogue with notable immunostimulatory properties. It has been shown to induce type I interferons in various animal models, thereby exhibiting antiviral effects. The functional activity of this compound is linked to the activation of Toll-like receptor 7 (TLR7). Additionally, 2′-O-2-Propyn-1-ylguanosine serves as a click chemistry reagent, featuring an alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
2′-O-2-Propyn-1-ylguanosine is a guanosine analogue with notable immunostimulatory properties. It has been shown to induce type I interferons in various animal models, thereby exhibiting antiviral effects. The functional activity of this compound is linked to the activation of Toll-like receptor 7 (TLR7). Additionally, 2′-O-2-Propyn-1-ylguanosine serves as a click chemistry reagent, featuring an alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
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