VCC234718 is a selective inhibitor of inosine monophosphate dehydrogenase (GuaB2), effectively targeting Mycobacterium tuberculosis (Mtb) to inhibit its growth. With a K value of 100 nM, VCC234718 exhibits non-competitive inhibition involving both IMP and NAD+, demonstrating its ability to disrupt enzymatic function through direct interactions with these metabolites. This compound is valuable for studying mycobacterial infections and developing new treatments for tuberculosis.
VCC234718 is a selective inhibitor of inosine monophosphate dehydrogenase (GuaB2), effectively targeting Mycobacterium tuberculosis (Mtb) to inhibit its growth. With a K value of 100 nM, VCC234718 exhibits non-competitive inhibition involving both IMP and NAD+, demonstrating its ability to disrupt enzymatic function through direct interactions with these metabolites. This compound is valuable for studying mycobacterial infections and developing new treatments for tuberculosis.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
