Microbiology

Shop By

Items 1751-1800 of 2061

Page
per page
Set Descending Direction
Catalog No.
Product Name
Application
Product Information
Citations
  1. HIV-1 nucleotide reverse transcriptase inhibitor

    Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.
  2. HIV-1 nucleotide reverse transcriptase inhibitor

    Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor.
  3. HCV NS5A inhibitor

    Ledipasvir acetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
  4. Fosfomycin calcium is a MurA and isopentenyl mevalonate kinase inhibitor that prevents synthesis of bacterial cell walls.
  5. EV capsid inhibitor

    Pocapavir is an investigational enterovirus (EV) capsid inhibitor.
  6. β-lactamase inhibitor

    AAI-101, also known as Enmetazobactam, is a beta lactamase inhibitor potentially for the treatment of multi-drug resistant gram-negative bacterial infections.
  7. NRT inhibitor

    GS-7340 is a prodrug of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than TFV disoproxil fumarate.
  8. Calcineurin/PP2B inhibitor

    Ascomycin is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties. It has been researched for the treatment of autoimmune diseases and skin diseases, and to prevent rejection after an organ transplant.
  9. HIV fusion inhibitor

    Enfuvirtide Acetate (T-20) is a 36 amino acid peptide corresponding to a region of gp41, the transmembrane subunit of HIV-1 envelope protein.
  10. Antiviral fusion inhibitor

    Presatovir is a novel, orally bioavailable RSV fusion inhibitor, against a wide range of RSV A and B clinical isolates (mean EC50 = 0.43 nM).
  11. HIV maturation inhibitor

    GSK2838232-isomer is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection.

  12. HIV integrase inhibitor

    GSK744 is a potent HIV integrase inhibitor as an oral lead-in tablet and long-acting injectable for the treatment and prevention of HIV infection.
  13. HIV integrase inhibitor

    BI 224436 is a novel HIV-1 non-catalytic-site integrase inhibitor; has antiviral EC50s of <15 nM against different HIV-1 laboratory strains and cellular cytotoxicity of >90 μM.
  14. Allosteric IN inhibitor

    (±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.
  15. HIV integrase inhibitor

    Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
  16. Thyroid inhibitor

    Aminothiazole can be used as a thyroid inhibitor and it has antibacterial activity.
  17. arachidonic acid metabolism inhibitor

    Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements.
  18. NS5A inhibitor

    Elbasvir is an NS5A inhibitor, preventing hepatitis C viral RNA replication and virion assembly. Median EC50 values range from 0.2 to 3600?pmol/L, based on genotype.
  19. Flavin Mononucleotide (FMN) Inhibitor

    Ribocil B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN) with a KD of 6.6 nM.
  20. HIV replication inhibitor

    ABX-464, also known as SPL-464, is an inhibitor of the HIV replication potentially for the treatment of HIV infection.
  21. plasmodium ATP4 inhibitor

    (+)-SJ733 is an inhibitor of plasmodium ATP4, leading to rapid clearance in vivo by inducing physical changes in infected, treated red cells.
  22. HCV NS3/4A protease inhibitor

    Glecaprevir, also known as ABT-493 and A-1282576, is a novel HCV NS3/4A protease inhibitor, with IC50 values ranging from 3.5 to 11.3 nM.
  23. dipeptidase inhibitor

    Cilastatin is an inhibitor of dipeptidase (dehydropeptidase I), a renal dipeptidase.
  24. CYP51 inhibitor

    Tebuconazole is a triazole fungicide used agriculturally to treat plant pathogenic fungi.
  25. protein kinase A inhibitor

    Warangalone is a prenylated isoflavone from the insecticidal plant Derris scandens that acts as a powerful inhibitor of protein kinase A.
  26. asparaginyl endopeptidases inhibitors

    RR-11a analog is a potent and selective inhibitors of asparaginyl endopeptidases (AE) (Legumain), with IC50 values of 4.5 nM, 4.5 nM and 31 nM for AE1 in Trichomonas Vaginalis, AE in Ixodes ricinus and AE in Schistosoma mansoni, respectively.
  27. Adenosine deaminase inhibitor

    EHNA hydrochloride is a specific inhibitor of adenosine deaminase, prevents dAdo degradation and increases mitochondrial dATP levels in fibroblasts.
  28. Protein synthesis inhibitor

    Blasticidin S is a nucleoside antibiotic isolated from Streptomyces griseochromogenes. Blasticidin S is a potent inhibitor of protein synthesis in both prokaryotic and eukaryotic cells.
  29. HCV RNA replication inhibitor

    PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
  30. HCV RNA replication inhibitor

    Sofosbuvir impurity C is the less active impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
  31. HCV RNA replication inhibitor

    Sofosbuvir impurity A, an diastereoisomer of sofosbuvir, is the impurity of sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
  32. HBV inhibitor

    Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV) with an IC50 of 53 nM.
  33. HCV NS5B polymerase inhibitor

    NM107 (2'-C-Methylcytidine) is an nucleoside inhibitor of the hepatitis C virus (HCV) NS5B polymerase, the EC50 of NM107 in the wild-type replicon cells is 1.85 μM.
  34. nucleotide reverse transcriptase inhibitor

    Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
  35. HCV NS5B polymerase inhibitor

    PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase.
  36. cyclophilin inhibitor

    Alisporivir (DEB-025; Debio-025) is a cyclophilin inhibitor molecule with potent anti-hepatitis C virus (HCV) activity.
  37. RSV polymerase inhibitor

    Lumicitabine (ALS-008176) is an inhibitor of the respiratory syncytial virus (RSV) polymerase.
  38. HBV inhibitor

    RG7834 (RO 7020322) is a highly selective and orally bioavailable HBV inhibitor, potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells.
  39. RSV replication inhibitor

    RSV604 R enantiomer is the R-enantiomer of RSV604. RSV604 is an inhibitor of respiratory syncytial virus (RSV) replication. R-enantiomer is less active against RSV.
  40. Cruzain inhibitor

    Cruzain-IN-1 is a covalent and reversible Cruzain inhibitor, with an IC50 of 10 nM.
  41. β-lactamase inhibitor

    Zidebactam sodium salt (WCK-5107 sodium salt) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.
  42. Topoisomerase inhibitor

    Zabofloxacin hydrochloride (DW-224a) is a novel fluoronaphthyridone quinolone that is considered a potent antibacterial candidate for clinical trials.
  43. non-nucleoside reverse transcriptase inhibitor

    Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 ?M for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells.
  44. efflux pump inhibitor

    PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor.
  45. FIPV inhibitor

    GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC50 of 0.78 μM.
  46. beta-lactamase inhibitor

    Sulopenem (CP-70429) is an orally active, potent inhibitor of beta-lactamase. Sulopenem is a parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria.
  47. SARS-CoV Mpro inhibitor

    XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM.
  48. Candida albicans filamentation inhibitor

    Filastatin is a long-lasting inhibitor of Candida albicans filamentation. Filastatin inhibits adhesion by multiple pathogenic Candida species with an IC50 of ~3 μM in the GFP-based adhesion assay.
  49. neuraminidase inhibitor

    Neuraminidase-IN-1 is a neuraminidase inhibitor, with an IC50 of 0.21 μM. Neuraminidase-IN-1 has excellent activity against H1N1 influenza virus.
  50. depalmitoylase inhibitor

    JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1.

Items 1751-1800 of 2061

Page
per page
Set Descending Direction