Catalog No.
Product Name
Application
Product Information
Citations
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Fungicide Agent
Fluconazole mesylate is a triazole antifungal agent that targets fungal sterol biosynthesis by inhibiting the enzyme lanosterol demethylase. It exhibits significant antifungal activity against a variety of pathogenic fungi, making it effective in the treatment and prevention of both superficial and systemic fungal infections. This compound is widely utilized in clinical research and can aid in the development of antifungal therapies. -
Topical Antimicrobial
Voxvoganan (LTX-109) is a topical antimicrobial agent that targets Staphylococcus aureus with a minimum inhibitory concentration (MIC) range of 2 to 4 μg/mL. It demonstrates potent activity against bacterial skin infections and fungal infections. Additionally, Voxvoganan is applicable in studies involving nasal decolonization of methicillin-resistant Staphylococcus aureus (MRSA). -
Microbial Inhibitor
Antifungal agent 38 is a heterocyclic disulfide that acts as a potent microbial inhibitor. Its primary mechanism involves inducing hyphal shrinkage and disrupting the integrity of the plasma membrane, leading to cellular damage and leakage of intracellular contents. This compound is valuable for research applications focused on antifungal and antibacterial activities, offering insights into cell membrane dynamics and potential therapeutic approaches against microbial infections. -
Antifungal Agent
Antifungal Agent 118 (compound C22) primarily targets hyphal growth in pathogens, specifically inhibiting the development of V. mali. Through the induction of oxidative damage, it effectively disrupts the integrity of the cell membrane, showcasing significant antifungal properties. This compound is valuable for research applications focused on studying fungal pathogenesis and developing antifungal strategies. -
Antifungal Agent/HIV-1 Inhibitor
Amphotericin B methyl ester hydrochloride is a derivative of the polyene antibiotic amphotericin B, functioning primarily as an antifungal agent. This compound exhibits potent antifungal activity by binding to cholesterol in fungal cell membranes, leading to cell death. Additionally, it disrupts HIV-1 particle production and significantly inhibits HIV-1 replication, making it valuable for research in antifungal therapies and HIV treatment studies. -
Antifungal Agent
3,5-Dimethoxybenzoic acid is an aromatic organic acid primarily noted for its antifungal properties. It demonstrates potent antifungal activity against A. rabiei, with a minimum inhibitory concentration (MIC) of 0.125 mg/mL. In addition to its antifungal applications, this compound serves as an important intermediate in the synthesis of anticancer agents. Furthermore, 3,5-Dimethoxybenzoic acid is recognized for its anti-wrinkle, anti-inflammatory, antioxidant, and skin regeneration effects. -
QoI-Type Fungicide
Orysastrobin is a QoI-type fungicide that acts as a quinone outside inhibitor, effectively targeting fungal respiration. It demonstrates potent fungicidal activity against rice diseases such as leaf and panicle blast, as well as sheath blight. This compound is valuable for agricultural research focused on improving crop protection strategies and enhancing yield in rice cultivation. -
Anti-Fungal Agent
NP213 is a first-in-class synthetic antimicrobial peptide that exhibits potent anti-fungal activity. It targets the fungal cytoplasmic membrane, inducing membrane perturbation and disruption, which leads to cell death. NP213 has demonstrated effectiveness in treating nail fungal infections, offering a well-tolerated option for clinical applications in antifungal therapy. -
Antitumor Antibiotic
Oligomycin E is an antitumor antibiotic derived from Streptomyces. It exhibits potent antifungal activity, with minimum inhibitory concentration (MIC) values ranging from 2 to 75 μg/mL. Oligomycin E demonstrates significant cytotoxicity against HeLa cells, exhibiting an IC50 of 0.014 μg/mL, making it valuable for investigations into cancer therapeutics and antifungal mechanisms. -
Antifungal Substance
Pyromeconic acid functions as an antifungal agent, exhibiting significant activity against various fungal pathogens. Its unique mechanism involves disrupting fungal cell wall synthesis, thereby inhibiting growth and proliferation. This compound is utilized in research applications aimed at understanding fungal biology and developing new antifungal therapies. -
Antifungal Antibiotic/Iron Chelator
Dihydroaeruginoic acid functions as an antifungal antibiotic and iron chelator. This thiazoline derivative, synthesized from salicylate and cysteine, effectively chelates Fe(III) and inhibits ribonucleotide reductase, leading to suppressed DNA replication and a G1/S cell cycle block. It demonstrates significant activity against phytopathogenic fungi and bacteria, notably inhibiting the growth of Candida albicans and preventing biofilm formation in Agrobacterium tumefaciens through iron sequestration. Dihydroaeruginoic acid is valuable for research into phytopathogenic infections and leukemia treatment strategies. -
metabolite
4'-Methyl-β-naphthoflavone is a metabolite derived from naphthoflavones, specifically showing activity as a modulator of cytochrome P450 enzymes. Its key biological activity involves the regulation of CYP-450, which is critical for various metabolic processes in fungi. This compound is valuable for research investigating the enzymatic pathways influenced by naphthoflavones and their implications in fungal biology. -
Antitumor Agent
Kievitone is an isoflavanone that demonstrates significant antitumor activity. Isolated from the hypocotyls of Phaseolus vulgaris L. infected by Rhizoctonia solani Kühn, Kievitone also exhibits antifungal properties. This compound serves as an important tool for researchers investigating cancer biology and the mechanisms of antifungal defense. -
Macrolide Antibiotic
Oligomycin C is a macrolide antibiotic that specifically inhibits ATP synthase, thereby disrupting mitochondrial function. This compound demonstrates potent antifungal activity against a range of pathogens, including Aspergillus niger, Alternaria alternata, Botrytis cinerea, and Phytophthora capsici, making it a valuable tool for studying fungal infections and mitochondrial bioenergetics. Its selective action on fungi, with no antibacterial activity, further emphasizes its utility in antifungal research applications. -
Secondary Metabolite
Neosartoricin B is a secondary metabolite produced by Aspergillus nidulans. It has been shown to exert immunomodulatory effects, potentially influencing host interactions during fungal infections and colonization. This compound serves as a valuable tool in research focused on fungal pathogenesis and host defense mechanisms. -
Antifungal Agent
Antifungal Agent 98 primarily targets fungal pathogens and exhibits significant antifungal activity. At a concentration of 100 μg/mL, it demonstrates efficacy against various harmful fungi, including Bipolaris sorokinianum, Fusarium oxysporium f. sp. vasinfectum, Pyricularia oryzae, Alternaria brassicae, and Alternaria alternata, achieving death rates of 41.5%, 40.0%, 23.4%, 36.8%, and 35.0%, respectively. This compound is valuable for research focused on fungal control and plant health management. -
Antifungal Agent
Antifungal Agent 48 is a potent antifungal compound targeting Cryptococcus neoformans. Demonstrating a minimum inhibitory concentration (MIC) of 11 μM, it exhibits significant antifungal activity. This reagent is suitable for research applications focused on fungal infections and the development of antifungal therapies. -
Antifungal Agent
Caulilexin C is a phytoalexin derived from cruciferous plants that exhibits potent antifungal properties. It plays a significant role in plant defense by inhibiting the growth of various fungal pathogens. This compound is of particular interest in agricultural research for developing antifungal strategies and understanding plant-fungal interactions. -
Fungicide
Phenamacril is a potent fungicide that non-competitively inhibits myosin I activity, achieving an IC50 of 360 nM by suppressing ATPase activity. This compound demonstrates significant antifungal efficacy against Fusarium species, making it a valuable tool for research in fungal pathogenesis and the development of antifungal agents. -
Serine Palmitoyltransferase Inhibitor
Lipoxamycin is a potent serine palmitoyltransferase inhibitor, exhibiting an IC50 of 21 nM. This compound demonstrates significant antifungal activity, making it a valuable tool for studying lipid metabolism and sphingolipid biosynthesis. Lipoxamycin is applicable in research focused on fungal infections and potential avenues for therapeutic interventions targeting lipid-related pathways. -
Antifungal Agent
Voriconazole N-oxide is a potent antifungal agent primarily targeting fungal cell membrane biosynthesis. This compound exhibits both phototoxic and photocarcinogenic properties, which are important considerations in its biological evaluation. Additionally, Voriconazole N-oxide does not sensitize keratinocytes to ultraviolet B (UVB), making it relevant for studies in dermatological applications and the investigation of keratinocyte response to UV exposure. -
Antibacterial Compound
Di-O-methylhonokiol is a natural phenolic compound with notable antibacterial properties. It exhibits significant activity against Gram-positive bacteria, acid-fast bacilli, and various yeast and filamentous fungi. This compound is valuable for research applications focused on fungal infections and the development of antibacterial agents. -
Antibacterial Agent
(±)9-HpODE is a long-chain lipid hydroperoxide derived from the peroxidation of linoleic acid. This compound can induce the oxidation of intracellular glutathione (GSH), leading to alterations in cellular redox state. Additionally, (±)9-HpODE demonstrates antibacterial and antifungal activity, making it a valuable reagent for research into microbial pathogenesis and oxidative stress responses. -
Metal Complex
Chlorotris(triphenylphosphine)copper (CuCl(TPP)₃) is a DNA-targeted metal complex that interacts with DNA through non-covalent binding mechanisms, primarily utilizing the copper(I) center. This compound exhibits significant biological activities, including antibacterial, antifungal, and antitumor effects. It is valuable for research applications focused on the development of novel antimicrobial and anticancer agents, as well as studies investigating antioxidant properties. -
Antifungal Agent
Harzianum A is a trichothecene compound with potent antifungal activity. While it exhibits no antibacterial effects against Gram-negative and Gram-positive bacteria, it demonstrates cytotoxicity towards tumor cells. This compound is valuable for research applications focused on fungal infections and cancer therapeutics. -
Fungicide
Sedaxane is a novel broad-spectrum fungicide that targets the succinate dehydrogenase complex in fungal mitochondria, effectively inhibiting fungal respiration. This compound demonstrates extensive activity against various seed-borne and soil-borne fungal pathogens. Sedaxane is particularly useful in studying barley loose smut and barley stripe disease, providing valuable insights into fungal resistance and pathogen interaction in agricultural research. -
Fungal
Metiram is a polymeric dithiocarbamate fungicide that acts by inhibiting fungal growth and reproduction. It is commonly utilized in agricultural settings to protect a variety of crops, including tomatoes, potatoes, apples, and grapevines, from fungal diseases. Metiram plays a critical role in integrated pest management strategies, particularly for controlling significant plant health threats that may not be effectively managed through non-chemical methods. -
SDH Iinhibitor
SDH-IN-5 is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 value of 3.293 μM. It exhibits significant antifungal activity, achieving an EC50 of 0.046 μg/mL against Rhizoctonia solani. In agricultural applications, SDH-IN-5 effectively inhibits the growth of R. solani in rice leaves, showcasing substantial protective and curative efficacies against this pathogen. -
Tau Aggregation Inhibitor
Nimbin is a potent tau aggregation inhibitor derived from the limonoid class of compounds found in Azadirachta. It is shown to enhance cell viability while effectively inhibiting the envelope protein of the dengue virus. Additionally, Nimbin exhibits a range of biological activities, including anti-inflammatory, antifungal, antihistamine, antiseptic, antioxidant, anticancer, and antiviral properties. This diverse activity profile makes Nimbin a valuable reagent for research in neurodegenerative diseases and viral infections. -
Antifungal agent
Tolprocarb is an antifungal agent that targets the polyketide synthase enzyme involved in melanin synthesis. It exhibits potent inhibitory activity against the rice blast fungus, Magnaporthe grisea. This compound is widely utilized in research applications focusing on fungal pathogen control and plant disease management. -
Antibacterial And Antifungal Agent
2,4-Dinitrobenzenesulfonamide is an antibacterial and antifungal agent that targets dihydrofolate synthetase. It exhibits significant inhibitory activity against various microorganisms, including Aspergillus niger, Candida albicans, Bacillus subtilis, and Staphylococcus aureus. This compound is valuable for research applications focused on antimicrobial activity and the study of folate metabolism. -
Antifungal Agent
2-Desfluoro fluconazole is an azole antifungal agent that functions by inhibiting ergosterol synthesis, disrupting fungal cell membrane integrity. It exhibits broad-spectrum antifungal activity, particularly against various Candida and Cryptococcus species. This compound is valuable for research applications aimed at studying antifungal resistance mechanisms and developing new therapeutic strategies against fungal infections. -
Pesticide
Mansonone E is a natural pesticide derived from the heartwood of Mansonia gagei, with a primary mechanism of antifungal and antibacterial activity. It exhibits significant antifungal efficacy against Cladosporium cucumerinum, Candida albicans, and Phytophthora parasitica. Mansonone E demonstrates potent antibacterial properties, with MIC50 values of 7.8 μg/mL against Xanthomonas oryzae pv. oryzae and X. oryzae pv. oryzicola. Additionally, it possesses antifeedant and herbicidal activities, making it a valuable compound for agricultural and environmental research applications. -
Fungal Inhibitor
2,4′-Dichloroacetanilide is a fungistatic agent that inhibits the growth of fungi by targeting key cellular processes. It demonstrates significant antifungal activity against Trichosporon asteroides, with a minimum inhibitory concentration (MIC) of 6.25 μg/mL. This compound is valuable for research applications involving fungal pathogenesis and the development of antifungal therapies. -
Antibacterial/Antifungal Agent
Cyclo(L-leucyl-L-tryptophyl) is a cyclic dipeptide known for its antibacterial and antifungal properties. It functions as a melatonin receptor agonist, contributing to its diverse biological activities. This reagent is often utilized in studies focusing on microbial inhibition and its potential therapeutic applications in infectious diseases. -
Antibacterial Agent
4-Methylbenzohydrazide is an antibacterial agent that exerts its activity against a range of microbial targets. It demonstrates a potent minimum inhibitory concentration (pMIC) value of 1.38 against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Aspergillus niger. This compound is suitable for research applications focused on developing antibacterial therapies and studying microbial resistance mechanisms. -
Antifungal
Chloramultilide B is a lindenane dimer that exhibits potent antifungal activity. It specifically inhibits the growth of Candida albicans and Candida parapsilosis, demonstrating a minimum inhibitory concentration (MIC) of 0.068 μM. This compound can be utilized in research focused on antifungal treatments and the study of fungal pathogenesis. -
Fungal Inhibitor
Cyclo(Pro-dArg) is a potent chitinase inhibitor, primarily targeting fungal cell wall integrity. It effectively disrupts cell separation in Saccharomyces cerevisiae while having no significant impact on its overall growth. Additionally, Cyclo(Pro-dArg) inhibits the morphological transition of Candida albicans from yeast to filamentous forms, making it valuable for research in fungal biology and antifungal drug development. -
Antifungal Agent
Antifungal agent 112 (Compound 1e) primarily targets fungal pathogens, demonstrating significant antifungal activity against Candida albicans, Aspergillus niger, and Aspergillus fumigatus, with minimum inhibitory concentrations (MIC) of 0.0024, 0.0022, and 0.0028 M, respectively. This compound is valuable for research applications focused on antifungal drug development and the study of fungal infections. Its potent efficacy may contribute to therapeutic strategies against resistant fungal strains. -
Antimicrobial Agent
3-Methoxy-2,5-toluquinone is an antimicrobial agent that exhibits moderate antibacterial and antifungal activity. It has potential applications in the study of infectious diseases and the development of novel therapeutic strategies. This compound serves as a valuable tool for researchers investigating the mechanisms of action of antimicrobial agents in various biological contexts. -
Fungicide
Ethaboxam is a β-tubulin inhibitor that effectively targets and disrupts the microtubule formation in fungi. This compound demonstrates potent anti-oomycete activity, making it a valuable tool in the study of plant-pathogenic fungi. Its mechanism of action provides insight into fungal cell division and offers potential applications in agricultural research and crop protection strategies. -
Antifungal Agent
Nitrofungin (2-Chloro-4-nitrophenol) is an antifungal agent that disrupts fungal cell membrane integrity. Its primary mechanism involves interference with ergosterol synthesis, making it a valuable tool for antifungal research. Nitrofungin is useful in studies focusing on fungal infections and the development of antifungal therapies. Additionally, it is of interest for examining microbial degradation pathways in environmental microbiology. -
Antimicrobial Drug
Somantadine is an antimicrobial agent known for its potent antimicrobial and antifungal properties. It acts by disrupting microbial cell membranes, thereby inhibiting growth and facilitating clearance of infections. This compound is valuable in research settings focused on developing therapies for bacterial and fungal infections. Its effectiveness makes it a significant candidate for studying antimicrobial resistance and evaluating new therapeutic strategies. -
Fungal
(±)-Voriconazole is a potent antifungal agent targeting fungal pathogens. It exhibits broad-spectrum activity against various fungi, including Candida and Aspergillus species, making it valuable in both clinical and research applications. This compound is primarily utilized to study antifungal resistance mechanisms and to explore novel therapeutic strategies for fungal infections. -
Antifungal Agent
Antifungal agent 143 is a potent compound primarily targeting fungal pathogens. This agent exhibits significant antifungal activity against Candida albicans and Aspergillus niger, as well as antibacterial effects against various bacterial strains including Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pyogenes. Antifungal agent 143 is suitable for research applications focused on antimicrobial activity and the development of new therapeutic strategies. -
Antifungal Agent
β-Phenylethyl β-D-glucoside is a phenolic compound that serves as an antifungal agent. It exhibits significant antifungal activity against Candida albicans, making it relevant for the study of fungal infections. This compound can be isolated from the leaves of Piper crocatum and is useful in researching antifungal therapies and mechanisms. -
Immunogen Hapten
Procymidone is an immunogen hapten that serves as a crucial element for the production of polyclonal antibodies when conjugated with carrier proteins such as cOVA. This compound exhibits antifungal activity, making it valuable for research applications in immunology and toxicology, particularly in studies investigating immune responses to chemical haptens and the mechanisms of antifungal action. -
Antifungal Agent
(10E,12E)-9-Oxo-10,12-octadecadienoic acid (9-oxo-ODA) serves as an antifungal agent and is recognized for its role as a PPARα agonist. Isolated from the basidiomycete Gomphus floccosus, it enhances fatty acid oxidation through PPARα activation, thereby inhibiting triglyceride accumulation. This compound is suitable for research applications focused on metabolic processes and fungal inhibition. -
Antimicrobial Agent
7-(Carboxymethoxy)-4-methylcoumarin is an antimicrobial agent known for its antibacterial and antifungal properties. It exhibits inhibitory activity against a range of pathogens, including Staphylococcus aureus, Bacillus cereus, Staphylococcus luteus, Candida albicans, Candida glabrata, and Candida parapsilosis. This compound is valuable for research applications targeting microbial infections and studying antimicrobial mechanisms. -
Antifungal Agent
(Z)-Lanoconazole is an imidazole antifungal agent characterized by its Z configuration. It exhibits potent activity against a wide range of fungi, both in vitro and in vivo, by inhibiting sterol 14-alpha demethylase, thus disrupting ergosterol biosynthesis in fungal membranes. This compound is valuable for research into dermatophytosis and onychomycosis, providing insights into fungal infections and therapeutic interventions.
