Ledipasvir acetone

Catalog No.: A18055

HCV NS5A inhibitor

Ledipasvir acetone

Ledipasvir acetone Chemical Structure

CAS NO. 1441674-54-9

Ledipasvir acetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.

Availability: In stock

Package Price Qty
5 mg
$75.00
10 mg
$95.00
50 mg
$260.00
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Biological Activity

Ledipasvir acetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.56 mL 52.79 mL 105.59 mL
0.5 mM 2.11 mL 10.56 mL 21.12 mL
1 mM 1.06 mL 5.28 mL 10.56 mL
5 mM 0.21 mL 1.06 mL 2.11 mL

*The above data is based on the productmolecular weight 947.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18055
Actions Inhibitor
CAS No. 1441674-54-9
Formula C52H60F2N8O7
M. Wt 947.09
Solubility DMSO
Purity >98%
Synonyms Ledipasvir acetone;
SMILES COC(N[[email protected]](C(N1CC2(C[[email protected]]1c3[nH]c(c4cc5c(c6c(C(F)5F)cc(c(cc7)cc8c7nc([[email protected]@H]9[[email protected]]%10CC[[email protected]@H](N9C([[email protected]](C(C)C)NC(OC)=O)=O)C%10)[nH]8)cc6)cc4)cn3)CC2)=O)C(C)C)=O.CC(C)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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