Dengue Virus

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  1. DENV NS2B-NS3 protease inhibitor

    ZINC03129319 is a dengue virus (DENV) NS2B-NS3 protease inhibitor extracted from patent US20150141521A1, has inhibition constants (Ki1) of 92±15 μM and Ki3 of 20±4 μM.
  2. cholesterol synthesis/Hedgehog inhibitor

    U18666A, a cell permeable drug, is a cholesterol synthesis and transport inhibitor.
  3. flaviviruse inhibitor

    NITD008 is a potent and selective flaviviruse inhibitor which can inhibit Dengue Virus Type 2 (DENV-2) with an EC50 of 0.64 μM.

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