Dolutegravir Sodium

Catalog No.: A16162

HIV integrase inhibitor

Dolutegravir Sodium

Dolutegravir Sodium Chemical Structure

CAS NO. 1051375-19-9

Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$95.00
50 mg
$399.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Targets
HIV integrase
2.7 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.66 mL 113.29 mL 226.57 mL
0.5 mM 4.53 mL 22.66 mL 45.31 mL
1 mM 2.27 mL 11.33 mL 22.66 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16162
Actions Inhibitor
M. Wt 441.36
Formula C20H18F2N3NaO5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1051375-19-9
Synonyms DTG, GSK1349572
SMILES CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]

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