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Ro 48-8071

Catalog No.: A14203

OSC Inhibitor

Ro 48-8071

Ro 48-8071 Chemical Structure

CAS NO. 161582-11-2

Ro 48-8071 is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.

Availability: In stock

Package Price Qty
10 mg
$70.00
25 mg
$160.00
50 mg
$250.00
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Biological Activity

Ro 48-8071 is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.3 mL 111.52 mL 223.03 mL
0.5 mM 4.46 mL 22.3 mL 44.61 mL
1 mM 2.23 mL 11.15 mL 22.3 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14203
Actions Inhibitor
CAS No. 161582-11-2
Formula C23H27BrFNO2
M. Wt 448.37
Purity >98%
Synonyms Ro-48-8071, Ro48-8071
SMILES CN(CCCCCCOC1=CC(=C(C=C1)C(=O)C2=CC=C(C=C2)Br)F)CC=C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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