Other inhibitors

Items 351-400 of 980

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  1. Sugammadex soidum is an agent for reversal of neuromuscular blockade by the agent rocuronium in general anaesthesia.
  2. ABHD6 inhibitor

    WWL70 is a potent inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50 = 70 nM), an enzyme which catalyzes the hydrolysis of 2-arachidonylglycerol.
  3. PPCE inhibitor

    Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor.
  4. 4-Aminobenzoic acid is an intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi.
  5. 4-Aminoantipyrine is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties.
  6. i-Inositol is a chemical compound which is sugar alcohol. i-Inositol is involved in a number of biological processes including insulin signal transduction, cytoskeleton transduction and so on.
  7. Citric acid trilithium salt tetrahydrate is a pharmaceutical and construction material.
  8. Selective chymase substrate

    RETF-4NA is a chymase substrate peptide that is cleaved more avidly by α2-macroglobulin-bound chymase than the free, unbound form.
  9. Prolyl endopeptidase inhibitor

    Y-29794 oxalate, inhibitor of prolyl endopeptidase, is a serine peptidase that may be implicated in the biosynthesis of amyloid β-peptide.
  10. Proprotein convertases inhibitor

    Decanoyl-RVKR-CMK is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases.
  11. ECE inhibitor

    CGS 35066 is a a potent endothelin-converting enzyme (ECE) inhibitor.
  12. furin inhibitor

    Hexa-D-arginine is a inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 uM for furin, PACE4 and PC1 respectively).
  13. Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.
  14. SSAO/VAP-1 inhibitor

    PXS-4728A is a very potent and highly selective compound in development for the treatment of cardiometabolic diseases like the liver-related disease Nonalcoholic Steatohepatitis (NASH).
  15. Complex III modulator

    S3QEL 2 is a selective inhibitor of superoxide production from the outer Q-binding site of mitochondrial respiratory complex site III (IIIQo) without altering oxidative phosphorylation.
  16. TACC3 inhibitor

    SPL-B, Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells.
  17. Butamben is a long-duration local anesthetic used for the treatment of chronic pain.
  18. LSC inhibitor

    BRD 7116 is a potent and selective Inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM).
  19. The single isomer, 6-Carboxyfluorescein, contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid.
  20. HA15 is a molecule that targets specifically BiP/GRP78/HSPA5.
  21. Hydroquinidine is an antiarrhythmic agent.
  22. Molsidomine is an orally active, long acting vasodilating drug. Molsidomine is metabolized in the liver to the active metabolite linsidomine.
  23. Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus.
  24. D panthenol is an alcoholic analogue of D-pantothenic acid and cholinergic agent.
  25. Oxybenzone is an organic compound used in sunscreens; provides broad-spectrum ultraviolet coverage, including UVB and short-wave UVA rays.
  26. Ademetionine disulfate tosylate is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases.
  27. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid; component of a number of hair and skin conditioners.
  28. Dehydrocholic acid is a synthetic bile acid, manufactured by the oxidation of cholic acid.
  29. RS-1 is a RAD51-stimulatory compound, which increases the DNA binding activity of RAD51.
  30. Sulisobenzone is an ingredient in some sunscreens which protects the skin from damage by UVB and short-wave UVA ultraviolet light.
  31. Glutathione acts as an antioxidant, a free radical scavenger and a detoxifying agent.
  32. L-tyrosine is a non-essential amino acid. In animals it is synthesized from Ephenylalanine.
  33. cell cycle inhibitor

    ON-013100 is a cell cycle inhibitor and is potentially useful for the treatment of mantle cell lymphoma.
  34. Fibrillogenesis inhibitor

    Eprodisate is an orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.
  35. SCH00013 is a cardiotonic agent that primarily acts via an increase in myofibrillar Ca++ sensitivity, have a significant Ca(2+)sensitizing effect at pH 7.2 to 7.4.
  36. VMAT2 inhibitor

    Valbenazine is a potent and selective VMAT2 inhibitor.
  37. Cytohesin inhibitor

    SecinH3 is a selective cytohesin inhibitor with IC50 of 2.4 μM, 5.4 μM, 5.4 μM, 5.6 μM, 5.6 μM, and 65 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, and yGea2-S7, respectively.
  38. 3,3'-Diindolylmethane(DIM) is a major digestive product of indole-3-carbinol, a potential anticancer component of cruciferous vegetables.
  39. HMN-176 is a stilbene derivative which inhibits mitosis without significant effect on tubulin polymerization.
  40. HTHQ, which is a hydroquinone monoalkyl ether, is a potent anti-oxidative agent, even at low dose levels.
  41. 2-Aminoheptane is a nasal decongestant drug which is a sympathomimetic stimulant and vasoconstrictor.
  42. 4-Aminohippuric acid is a typical substrate of organic anion transport systems.
  43. 6-Acetamidohexanoic acid is a pharmaceutical intermediate.
  44. Aceglutamide is a psychostimulant, nootropic agent which functions as a prodrug to glutamine with improved potency and stability.
  45. Acesulfame potassium is a non-nutritive sweetener.
  46. Acetylleucine is a drug used in the treatment of vertigo.
  47. Aminoguanidine is a diamine oxidase and nitric oxide synthase inhibitor. It acts to reduce levels of advanced glycation end products (AGEs) through interacting with 3-deoxyglucosone.
  48. Antimony potassium tartrate trihydrate is a powerful emetic, also used in the treatment of schistosomiasis and leishmaniasis.
  49. Azaguanine-8 is a purine analogs showing antineoplastic activity by competing with guanine in the metabolism.

Items 351-400 of 980

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