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  1. Alpha-galactosidase inhibitor

    Deoxygalactonojirimycin Hydrochloride is a potent and selective Alpha-gal A (Alpha-galactosidase) inhibitor.
  2. squalene epoxidase inhibitor

    NB-598 is a potent competitive inhibitor of squalene epoxidase.
  3. PDHK inhibitor

    AZD7545 is a novel, selective small-molecule inhibitor of PDHK2 (PDH kinase2) with an IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2 respectively.
  4. OSC Inhibitor

    Ro 48-8071 is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.
  5. NQO1 inhibitor

    Dicoumarol is a competitive NADH quinone oxidoreductase (NQO1) inhibitor.
  6. cholinephosphotransferase inhibitor

    Meclofenoxate HCl is an anti-aging drug used to treat the symptoms of senile dementia and Alzheimer's disease, and also inhibits the activity of cholinephosphotransferase.
  7. cPLA2α inhibitor

    CAY10650 is a highly potent (IC50 = 12 nM) cPLA2α inhibitor.
  8. Factor VIIa Inhibitor

    PCI-27483 is a reversible small-molecule inhibitor of activated factor VII (factor VIIa) with potential antineoplastic and antithrombotic activities.
  9. beta-hexosaminidase inhibitor

    AB05831 is a highly potent and specific inhibitor of beta-hexosaminidase.
  10. TGH inhibitor

    GR148672X is a TGH inhibitor.
  11. RPA inhibitor

    HAMNO, also known as NSC-111847, is a potent and selective inhibitor of replication protein A (RPA) interactions with proteins involved in the replication stress response.
  12. PME-1 inhibitor

    AMZ30 is a selective, covalent inhibitors of protein phosphatase methylesterase-1(PME-1) with IC50 value of 600 nM.
  13. MPI inhibitor

    MLS0315771 is a potent competitive phosphomannose isomerase (MPI) inhibitor.
  14. ABHD16A inhibitor

    KC01 is a covalent inhibitor of ABHD16A.
  15. SEC inhibitor

    KL-1 is an inhibitor of SEC and transcription elongation by Pol II which disrupts the cyclin T1-AFF4 interaction within SEC, and attenuates SEC-dependent rapid transcriptional responses. KL-1 inhibits MYC transcriptional programs.
  16. PEPCK inhibitor

    SKF-34288 hydrochloride (3-Mercaptopicolinic acid) is a phosphoenolpyruvate carboxykinase (PEPCK) inhibitor. SKF-34288 hydrochloride is a potent hypoglycemic agent via inhibition of glucose synthesis through the specific inhibition of PEPCK in the gluconeogenesis pathway.
  17. NAC1 inhibitor

    NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity.
  18. FER tyrosine kinase inhibitor

    DS21360717 is a potent and orally active FER tyrosine kinase inhibitor, with an IC50 of 0.49 nM. Anti-cancer activity.
  19. DprE1 inhibitor

    AZ7371 is a a novel non-covalent DprE1 inhibitor.
  20. arginase inhibitor

    BEC HCl is a slow-binding, and competitive arginase inhibitor with Ki of 0.31 μM (pH7.5) and 0.4-0.6 μM for Arginase II and rat Arginase I, respectively.
  21. polyamine synthesis inhibitor

    Sardomozide is a second-generation polyamine synthesis inhibitor, which inhibits the activity of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (SAMDC).
  22. ABHD6 inhibitor

    WWL70 is a potent inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50 = 70 nM), an enzyme which catalyzes the hydrolysis of 2-arachidonylglycerol.
  23. PPCE inhibitor

    Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopeptidase (PPCE) inhibitor.
  24. Prolyl endopeptidase inhibitor

    Y-29794 oxalate, inhibitor of prolyl endopeptidase, is a serine peptidase that may be implicated in the biosynthesis of amyloid β-peptide.
  25. Proprotein convertases inhibitor

    Decanoyl-RVKR-CMK is a selective, irreversible, and cell-permeable competitive inhibitor of proprotein convertases.
  26. ECE inhibitor

    CGS 35066 is a a potent endothelin-converting enzyme (ECE) inhibitor.
  27. furin inhibitor

    Hexa-D-arginine is a inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 uM for furin, PACE4 and PC1 respectively).
  28. SSAO/VAP-1 inhibitor

    PXS-4728A is a very potent and highly selective compound in development for the treatment of cardiometabolic diseases like the liver-related disease Nonalcoholic Steatohepatitis (NASH).
  29. TACC3 inhibitor

    SPL-B, Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells.
  30. LSC inhibitor

    BRD 7116 is a potent and selective Inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM).
  31. cell cycle inhibitor

    ON-013100 is a cell cycle inhibitor and is potentially useful for the treatment of mantle cell lymphoma.
  32. Fibrillogenesis inhibitor

    Eprodisate is an orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis.
  33. VMAT2 inhibitor

    Valbenazine is a potent and selective VMAT2 inhibitor.
  34. Cytohesin inhibitor

    SecinH3 is a selective cytohesin inhibitor with IC50 of 2.4 μM, 5.4 μM, 5.4 μM, 5.6 μM, 5.6 μM, and 65 μM for hCyh2, hCyh1, mCyh3, hCyh3, drosophila steppke, and yGea2-S7, respectively.
  35. Stemness kinase inhibitor

    Amcasertib (BBI503), a first-in-class cancer stemness kinase inhibitor, is claimed to inhibit Nanog and other CSC pathways by targeting kinases with potential anticancer activity.
  36. Rio2 kinase (RIOK2) inhibitor

    NSC139021 (ERGi-USU) is a highly selective inhibitor for the growth of ERG-positive cancer cells with IC50s ranging from 30 to 400 nM.
  37. Type-I Kinase Inhibitor

    VI-16832 is a broad spectrum type-I kinase inhibitor
  38. LOXL2 inhibitor

    LOXL2-IN-1 HCl is a selective LOXL2 inhibitor with an IC50 of 126 nM.
  39. Heterotrimeric G-protein complex inhibitor

    PH-064 (BIM-46187) is an inhibitor of heterotrimeric G-protein complex.
  40. chymase inhibitor

    TY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively.
  41. Glyoxalase I (GLO1) inhibitor

    Glyoxalase I inhibitor (free base) is a potent Glyoxalase I (GLO1) inhibitor, candidate for anticancer agents.
  42. squalene epoxidase inhibitor

    FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.
  43. triazole DAGL(α) inhibitor

    DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100.
  44. enkephalin degrading enzymes inhibitor

    Kelatorphan is a full inhibitor of enkephalin degrading enzymes.
  45. CDC7 kinase inhibitor

    (R)-Simurosertib ((R)-TAK-931) is the (R)-enantiomer of Simurosertib, Simurosertib (TAK-931) is a selective cycle 7 (CDC7) kinase inhibitor, with an IC50<0.3 nM.
  46. SAMDC inhibitor

    Sardomozide is an S-adenosylmethionine decarboxylase (SAMDC) inhibitor with an IC50 of 5 nM.
  47. VP40 Inhibitor

    ASN03576800 is an inhibitor of the VP40 matrix protein.
  48. Ces3 inhibitor

    WWL229 is a selective inhibitor of Ces3 that acts by inhibiting recombinant Ces3 and recapitulating the effects of WWL113 in adipocytes.
  49. polymerase inhibitor

    ERDRP-0519 is an orally available inhibitor of polymerase that shows efficacy against a lethal morbillivirus infection in a large animal model.
  50. p18INK inhibitor

    NSC23005 is a p18INK inhibitor. NSC23005 potently promotes hematopoietic stem cell (HSC) expansion (ED50 = 5.21 nM).

Items 51-100 of 218

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