KL-1

Catalog No.: A18418

SEC inhibitor

KL-1

KL-1 Chemical Structure

CAS NO. 900308-84-1

KL-1 is an inhibitor of SEC and transcription elongation by Pol II which disrupts the cyclin T1-AFF4 interaction within SEC, and attenuates SEC-dependent rapid transcriptional responses. KL-1 inhibits MYC transcriptional programs.

Availability: In stock

Package Price Qty
1 mg
$60.00
5 mg
$280.00
10 mg
$460.00
50 mg
$680.00
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Biological Activity

KL-1 is an inhibitor of SEC and transcription elongation by Pol II which disrupts the cyclin T1-AFF4 interaction within SEC, and attenuates SEC-dependent rapid transcriptional responses. KL-1 inhibits MYC transcriptional programs.
In vitro DMSO 64 mg/mL (185.08 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.92 mL 144.6 mL 289.2 mL
0.5 mM 5.78 mL 28.92 mL 57.84 mL
1 mM 2.89 mL 14.46 mL 28.92 mL
5 mM 0.58 mL 2.89 mL 5.78 mL

*The above data is based on the productmolecular weight 345.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18418
Actions Inhibitor
CAS No. 900308-84-1
Formula C18H16ClNO4
M. Wt 345.78
Purity >98%
Synonyms KL1; KL 1; KL-1
SMILES O=C(NC1=CC(Cl)=CC=C1C)C(CC(C2=CC=CC(OC)=C2)=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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