KL-1

Catalog No.: A18418

SEC inhibitor

KL-1

KL-1 Chemical Structure

CAS NO. 900308-84-1

KL-1 is an inhibitor of SEC and transcription elongation by Pol II which disrupts the cyclin T1-AFF4 interaction within SEC, and attenuates SEC-dependent rapid transcriptional responses. KL-1 inhibits MYC transcriptional programs.

Availability: In stock

Package Price Qty
1 mg
$60.00
5 mg
$280.00
10 mg
$460.00
50 mg
$680.00
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Biological Activity

KL-1 is an inhibitor of SEC and transcription elongation by Pol II which disrupts the cyclin T1-AFF4 interaction within SEC, and attenuates SEC-dependent rapid transcriptional responses. KL-1 inhibits MYC transcriptional programs.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.92 mL 144.6 mL 289.2 mL
0.5 mM 5.78 mL 28.92 mL 57.84 mL
1 mM 2.89 mL 14.46 mL 28.92 mL
5 mM 0.58 mL 2.89 mL 5.78 mL

*The above data is based on the productmolecular weight 345.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18418
Actions Inhibitor
M. Wt 345.78
Formula C18H16ClNO4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 900308-84-1
Synonyms KL1; KL 1; KL-1
SMILES O=C(NC1=CC(Cl)=CC=C1C)C(CC(C2=CC=CC(OC)=C2)=O)=O

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