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Bombolitin IV

Catalog No.: A49778
Antimicrobial Peptide
Bombolitin IV is an antimicrobial peptide derived from bumblebee venom, known for its ability to disrupt membrane integrity. This compound exhibits potent lytic activity against erythrocytes and liposomes, making it a valuable tool for studying membrane-targeting mechanisms. Its applications extend to antimicrobial research, providing insights into new therapeutic strategies against resistant pathogens.
Bombolitin IV 95753-40-5 Antimicrobial Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBombolitin IV is an antimicrobial peptide derived from bumblebee venom, known for its ability to disrupt membrane integrity. This compound exhibits potent lytic activity against erythrocytes and liposomes, making it a valuable tool for studying membrane-targeting mechanisms. Its applications extend to antimicrobial research, providing insights into new therapeutic strategies against resistant pathogens.
Product Information
Catalog NumA49778
FormulaC88H158N24O20
Molecular Weight1872.34
CAS Number95753-40-5
SequenceIle-Asn-Ile-Lys-Asp-Ile-Leu-Ala-Lys-Leu-Val-Lys-Val-Leu-Gly-His-Val-NH2
Sequence shorteningINIKDILAKLVKVLGHV-NH2
SMILES[C@H](CC1=CN=CN1)(C(N[C@@H](C(C)C)C(N)=O)=O)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CC(N)=O)=O)[C@H](CC)C)=O)CCCCN)=O)CC(O)=O)=O)[C@H](CC)C)=O)CC(C)C)=O)C)=O)CCCCN)=O)CC(C)C)=O)C(C)C)=O)CCCCN)=O)C(C)C)=O)CC(C)C)=O)=O
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