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AMPR-22

Catalog No.: A49440
Antimicrobial Peptide
AMPR-22 is an antimicrobial peptide that interacts with bacterial membranes to induce membrane permeabilization. This compound exhibits significant antimicrobial activity, effectively targeting multidrug-resistant (MDR) strains in preclinical murine models of sepsis. AMPR-22 is a valuable tool for researchers investigating novel antimicrobial agents and strategies to combat antibiotic resistance.
AMPR-22 2569135-98-2 Antimicrobial Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAMPR-22 is an antimicrobial peptide that interacts with bacterial membranes to induce membrane permeabilization. This compound exhibits significant antimicrobial activity, effectively targeting multidrug-resistant (MDR) strains in preclinical murine models of sepsis. AMPR-22 is a valuable tool for researchers investigating novel antimicrobial agents and strategies to combat antibiotic resistance.
Product Information
Catalog NumA49440
FormulaC98H168N28O22S3
Molecular Weight2186.75
CAS Number2569135-98-2
SequenceLys-Lys-Met-Met-Lys-Lys-Gly-Gly-Lys-Phe-Gly-Thr-Phe-Met-Ala-Ile-Gly-Gly-Ile-Arg
Sequence shorteningKKMMKKGGKFGTFMAIGGIR
SMILES[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)[C@H](CC)C)=O)=O)=O)[C@H](CC)C)=O)C)=O)CCSC)=O)NC([C@@H](NC(CNC([C@H](CC2=CC=CC=C2)NC([C@@H](NC(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)CCCCN)=O)CCSC)=O)CCSC)=O)CCCCN)=O)CCCCN)=O)=O)=O)CCCCN)=O)=O)=O)[C@@H](C)O)=O
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