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Drosocin

Catalog No.: A49524
Bioactive Peptide
Drosocin is a bioactive peptide derived from Drosophila melanogaster that functions as a cationic antimicrobial agent. It exhibits significant antibacterial activity, which makes it a valuable tool for studying innate immunity and developing antimicrobial therapies. This synthetic variant retains the original 19-amino acid sequence but lacks the native disaccharide moiety, allowing for comprehensive research on peptide structure-activity relationships and applications in infectious disease models.
Drosocin 149924-99-2 Bioactive Peptide
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDrosocin is a bioactive peptide derived from Drosophila melanogaster that functions as a cationic antimicrobial agent. It exhibits significant antibacterial activity, which makes it a valuable tool for studying innate immunity and developing antimicrobial therapies. This synthetic variant retains the original 19-amino acid sequence but lacks the native disaccharide moiety, allowing for comprehensive research on peptide structure-activity relationships and applications in infectious disease models.
Product Information
Catalog NumA49524
FormulaC98H160N34O24
Molecular Weight2198.53
CAS Number149924-99-2
SequenceGly-Lys-Pro-Arg-Pro-Tyr-Ser-Pro-Arg-Pro-Thr-Ser-His-Pro-Arg-Pro-Ile-Arg-Val
Sequence shorteningGKPRPYSPRPTSHPRPIRV
SMILESC([C@H](CC1=CN=CN1)NC([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC(=O)[C@H]5N(C([C@H](CCCCN)NC(CN)=O)=O)CCC5)CCCNC(=N)N)=O)CCC4)CC6=CC=C(O)C=C6)=O)CO)=O)CCC3)CCCNC(=N)N)=O)CCC2)[C@@H](C)O)=O)CO)=O)(=O)N7[C@H](C(N[C@H](C(=O)N8[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](C)C)C(O)=O)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)CCC8)CCCNC(=N)N)=O)CCC7
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