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Mram 8

Catalog No.: A49412
Plant Peptide
Mram 8 is a cyclotide derived from Viola philippica, a member of the Violaceae family. This plant peptide exhibits unique structural properties that contribute to its stability and biological activity. Mram 8 is of particular interest for research applications involving peptide synthesis, functional studies of plant-derived compounds, and exploration of potential therapeutic uses in agriculture and biotechnology.
Mram 8 1803183-45-0 Plant Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMram 8 is a cyclotide derived from Viola philippica, a member of the Violaceae family. This plant peptide exhibits unique structural properties that contribute to its stability and biological activity. Mram 8 is of particular interest for research applications involving peptide synthesis, functional studies of plant-derived compounds, and exploration of potential therapeutic uses in agriculture and biotechnology.
Product Information
Catalog NumA49412
FormulaC132H208N36O39S6
Molecular Weight3115.67
CAS Number1803183-45-0
SequenceCyclo(Ala-Ile-Gly-Cys-Ser-Cys-Lys-Ser-Lys-Val-Cys-Tyr-Arg-Asn-Gly-Ile-Pro-Cys-Gly-Glu-Ser-Cys-Val-Phe-Ile-Pro-Cys-Leu-Thr-Ser) (Disulfide bridge: Cys4-Cys18,Cys6-Cys22,Cys11-Cys27)
Sequence shorteningCyclo(AIGCSCKSKVCYRNGIPCGESCVFIPCLTS) (Disulfide bridge: Cys4-Cys18,Cys6-Cys22,Cys11-Cys27)
SMILESO=C1N2[C@@](CCC2)(C(=O)N[C@@]3(C(=O)N[C@@H](CC(C)C)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@]([C@H](CC)C)(C(=O)NCC(=O)N[C@@]4(C(=O)N[C@@H](CO)C(=O)N[C@]5(CSSC[C@@](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N[C@]1([C@H](CC)C)[H])(NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@](NC(=O)[C@]7(N(C(=O)[C@]([C@H](CC)C)(NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC8=CC=C(O)C=C8)NC(=O)[C@](CSSC3)(NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC5=O)[H])[H])CCC7)[H])(CSSC4)[H])[H])[H])[H])[H])[H])[H])[H]
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