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BING

Catalog No.: A49755
Antimicrobial Peptide
BING is an antimicrobial peptide derived from Japanese medaka fish, targeting pathogenic bacteria with a broad-spectrum antibacterial activity, including effectiveness against drug-resistant strains. Its mechanism involves the deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, leading to a reduction in cpxR RNA levels, which are essential for antimicrobial resistance development. BING is a valuable tool for research in antimicrobial resistance and the development of novel therapeutic strategies.
BING 2396407-35-3 Antimicrobial Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBING is an antimicrobial peptide derived from Japanese medaka fish, targeting pathogenic bacteria with a broad-spectrum antibacterial activity, including effectiveness against drug-resistant strains. Its mechanism involves the deregulation of periplasmic peptidyl-prolyl isomerases in gram-negative bacteria, leading to a reduction in cpxR RNA levels, which are essential for antimicrobial resistance development. BING is a valuable tool for research in antimicrobial resistance and the development of novel therapeutic strategies.
Product Information
Catalog NumA49755
FormulaC67H125N21O15
Molecular Weight1464.84
CAS Number2396407-35-3
SequenceIle-Arg-Ile-Ile-Leu-Arg-Ala-Gln-Gly-Ala-Leu-Lys-Ile
Sequence shorteningIRIILRAQGALKI
SMILES[C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H]([C@H](CC)C)C(O)=O)=O)CCCCN)=O)CC(C)C)=O)C)=O)=O)CCC(N)=O)=O)C)=O)CCCNC(=N)N)=O)CC(C)C)=O)[C@H](CC)C
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