[Lys3]-Bombesin is a bioactive peptide that targets the gastrin-releasing peptide receptor (GRPR). Its primary application includes PET imaging for detecting GRPR-positive prostate cancer, facilitating non-invasive tumor visualization. Additionally, [Lys3]-Bombesin can be utilized in immunoconjugates with monoclonal antibodies to selectively induce CD64-dependent lysis of small cell carcinoma by monocytes and neutrophils, providing insights into targeted cancer therapies.
[Lys3]-Bombesin is a bioactive peptide that targets the gastrin-releasing peptide receptor (GRPR). Its primary application includes PET imaging for detecting GRPR-positive prostate cancer, facilitating non-invasive tumor visualization. Additionally, [Lys3]-Bombesin can be utilized in immunoconjugates with monoclonal antibodies to selectively induce CD64-dependent lysis of small cell carcinoma by monocytes and neutrophils, providing insights into targeted cancer therapies.
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