Garvicin KS, GakC is a 32-amino acid peptide that acts as a bacteriocin, specifically targeting the GarKS peptide. This compound exhibits significant antibacterial activity, particularly against Methicillin-Sensitive Staphylococcus aureus (MSSA), with minimal inhibitory concentration (MIC) values revealing a potency hierarchy of GakB > GakC > GakA. Additionally, Garvicin KS, GakC has been shown to inhibit fibroblast viability and proliferation, making it valuable for investigating antibacterial mechanisms and cellular responses in research applications.
Garvicin KS, GakC is a 32-amino acid peptide that acts as a bacteriocin, specifically targeting the GarKS peptide. This compound exhibits significant antibacterial activity, particularly against Methicillin-Sensitive Staphylococcus aureus (MSSA), with minimal inhibitory concentration (MIC) values revealing a potency hierarchy of GakB > GakC > GakA. Additionally, Garvicin KS, GakC has been shown to inhibit fibroblast viability and proliferation, making it valuable for investigating antibacterial mechanisms and cellular responses in research applications.
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