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Retrocyclin-2

Catalog No.: A49402
Antimicrobial Peptide
Retrocyclin-2 is an antimicrobial peptide primarily targeting viral infections. It exhibits potent activity against human immunodeficiency virus (HIV), influenza A, and herpes simplex virus (HSV). This compound is valuable for research applications focused on antiviral therapeutics and the study of peptide-based resistance mechanisms.
Retrocyclin-2 724760-20-7 Antimicrobial Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRetrocyclin-2 is an antimicrobial peptide primarily targeting viral infections. It exhibits potent activity against human immunodeficiency virus (HIV), influenza A, and herpes simplex virus (HSV). This compound is valuable for research applications focused on antiviral therapeutics and the study of peptide-based resistance mechanisms.
Product Information
Catalog NumA49402
FormulaC78H137N33O18S6
Molecular Weight2017.52
CAS Number724760-20-7
SequenceCyclo(Arg-Arg-Ile-Cys-Arg-Cys-Ile-Cys-Gly-Arg-Gly-Ile-Cys-Arg-Cys-Ile-Cys-Gly) (Disulfide bridge:Cys4-Cys17;Cys6-Cys15;Cys8-Cys13)
Sequence shorteningCyclo(RRICRCICGRGICRCICG) (Disulfide bridge:Cys4-Cys17;Cys6-Cys15;Cys8-Cys13)
SMILESO=C1[C@]2(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@]3(NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)[C@](CSSC3)(NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@](CSSC2)(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@]4(CSSC[C@](NC(=O)[C@]([C@H](CC)C)(N1)[H])(C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@]([C@H](CC)C)(C(=O)N4)[H])[H])[H])[H])[H])[H])[H])[H])[H]
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