Neuropeptide Y (human) free acid

Catalog No.: A62254
Neuropeptide
Neuropeptide Y (human) free acid is the deamidated variant of Neuropeptide Y, a key neuropeptide involved in various physiological processes. This compound lacks amidation at the C-terminal tyrosine, which is essential for triggering G protein signaling pathways. Its study is crucial for understanding neuropeptide signaling mechanisms, potential roles in appetite regulation, stress response, and various neurological disorders. This reagent is valuable for research in neurobiology and pharmacology, particularly in exploring the functional implications of peptide modifications.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNeuropeptide Y (human) free acid is the deamidated variant of Neuropeptide Y, a key neuropeptide involved in various physiological processes. This compound lacks amidation at the C-terminal tyrosine, which is essential for triggering G protein signaling pathways. Its study is crucial for understanding neuropeptide signaling mechanisms, potential roles in appetite regulation, stress response, and various neurological disorders. This reagent is valuable for research in neurobiology and pharmacology, particularly in exploring the functional implications of peptide modifications.
Product Information
Catalog NumA62254
FormulaC189H284N54O58S
Molecular Weight4272.67
CAS Number99575-89-0
SequenceTyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr
Sequence shorteningYPSKPDNPGEDAPAEDMARYYSALRHYINLITRQ
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