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Neuropeptide Y (22-36)

Catalog No.: A62258
Y2 Receptor Agonist
Neuropeptide Y (22-36) is a peptide fragment that acts as a selective agonist for the Y2 receptor. With subnanomolar affinity, it modulates various physiological processes, including appetite regulation, circadian rhythms, and stress response. This compound is valuable in neurobiological research, particularly in studies exploring the role of neuropeptides in neuroendocrine function and behavioral responses.
Neuropeptide Y (22-36) 119019-65-7 Y2 Receptor Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNeuropeptide Y (22-36) is a peptide fragment that acts as a selective agonist for the Y2 receptor. With subnanomolar affinity, it modulates various physiological processes, including appetite regulation, circadian rhythms, and stress response. This compound is valuable in neurobiological research, particularly in studies exploring the role of neuropeptides in neuroendocrine function and behavioral responses.
Product Information
Catalog NumA62258
FormulaC85H139N29O21
Molecular Weight1903.19
CAS Number119019-65-7
SequenceSer-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
Sequence shorteningSALRHYINLITRQRY-NH2
SMILES[C@@H](CC1=CC=C(O)C=C1)(NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CO)N)=O)C)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N)=O)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)CC(C)C)=O)CC(N)=O)=O)[C@H](CC)C)=O
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