Catalog No.
Product Name
Application
Product Information
Citations
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PROTAC Linker
2-(4-(Aminomethyl)piperidin-1-yl)ethanol is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to an E3 ubiquitin ligase, enabling selective degradation of specific proteins within the cell. Its application in chemical biology research allows for the investigation of protein functions and the development of innovative therapeutic strategies. -
PROTAC Linker
tert-Butyl 4-(azetidin-3-yl)piperazine-1-carboxylate functions as a PROTAC (Proteolysis Targeting Chimera) linker, facilitating the design and synthesis of targeted protein degraders. This compound enables the selective degradation of specific proteins, making it valuable for research applications in targeted therapy and cellular regulation studies. Its structural properties support the formation of stable PROTACs, thus advancing drug discovery and development initiatives. -
PROTAC Linker
Tert-butyl 4-(3-aminopropyl)piperidine-1-carboxylate is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in connecting ligand-binding domains to E3 ubiquitin ligases, enabling targeted degradation of specific proteins within cellular pathways. Its application in drug development and biochemical research supports the advancement of innovative therapeutic strategies. -
PROTAC Linker
Tert-butyl 4-(3-chloropropyl)piperazine-1-carboxylate serves as a versatile PROTAC linker, facilitating the development of proteolysis targeting chimeras. This compound plays a crucial role in molecular design by enabling the selective degradation of target proteins. Its application supports valuable research in targeted protein degradation and therapeutic interventions in various diseases. -
PROTAC Linker
tert-Butyl (5-iodopentyl)carbamate serves as a PROTAC linker, facilitating the development of targeted protein degraders. Its structure enables the effective connection of E3 ligases to the protein of interest, enhancing the recruitment and degradation of specific targets in cellular assays. This compound is essential for researchers exploring the potential of PROTAC technology in therapeutic applications. -
PROTAC Linker
1-Iodo-2-(2-iodoethoxy)ethane serves as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound's unique structure allows for efficient ubiquitination and subsequent degradation of target proteins, making it a valuable tool in targeted protein degradation studies. Researchers can utilize this linker in various applications within chemical biology and drug discovery targeting specific protein interactions. -
PROTAC Linker
4-Bromo-N-methylbutan-1-amine hydrobromide is a PROTAC linker designed to facilitate the synthesis of PROTACs. This compound plays a crucial role in assembling a bifunctional molecule that can simultaneously engage a target protein and an E3 ligase, leading to targeted protein degradation. It is an essential building block for researchers developing protein degradation strategies in various biological contexts. -
PROTAC Linker
Boc-azaspiro[3.3]heptane-NH-Me is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the selective degradation of target proteins by promoting the recruitment of E3 ligases. Its unique structural features contribute to effective molecular interactions, making it a valuable tool in targeted protein degradation studies and drug discovery applications. -
PROTAC Linker
Ethyl 7-aminoheptanoate hydrochloride functions as a PROTAC linker, facilitating the assembly of proteins for targeted degradation. This compound is instrumental in the development of proteolysis-targeting chimeras (PROTACs), enabling researchers to selectively degrade specific proteins within cellular environments. Its structural properties make it ideal for enhancing the efficacy of drug discovery and development in cancer research and other therapeutic areas. -
PROTAC Linker
3-(1-{[(9h-fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)propanoic acid serves as a versatile PROTAC linker, facilitating the assembly of targeted protein degradation agents. Its structure enables the effective conjugation of ligand pairs, promoting selective degradation of target proteins via the ubiquitin-proteasome system. This reagent is instrumental in the development of innovative therapeutic strategies for various diseases, including cancer. -
PROTAC Linker
tert-Butyl N-({3-aminobicyclo[1.1.1]pentan-1-yl}methyl)carbamate functions as a PROTAC linker, facilitating the design and synthesis of targeted protein degraders. This compound plays a crucial role in the construction of PROTACs, enabling selective degradation of protein targets via the ubiquitin-proteasome system. Researchers can utilize this reagent in various applications involving targeted protein modulation and therapeutic development. -
PROTAC Linker
tert-Butyl(4-iodobutoxy)dimethylsilane is a versatile PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enables the effective conjugation of target proteins to E3 ligases, facilitating targeted protein degradation. Its utility in the development of novel therapeutic strategies highlights its importance in chemical biology and drug discovery. -
PROTAC Linker
Piperazine-CH2-propargyl is a versatile PROTAC linker designed for the synthesis of protein-targeting chimeras. It facilitates targeted protein degradation by connecting a ligand to an E3 ligase recruiting component, enabling selective degradation of specific proteins. This compound is essential for researchers aiming to develop novel PROTACs for therapeutic applications in cancer and other diseases. -
PROTAC Linker
1,11-Dibromoundecane functions as a PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This bifunctional molecule is essential for promoting the selective degradation of target proteins through the recruitment of E3 ligases. It serves as a valuable tool in drug discovery and development, particularly in the study of targeted protein degradation pathways. -
PROTAC Linker
4-[[(1,1-Dimethylethoxy)carbonyl]amino]benzeneacetic acid acts as a PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in the targeted degradation of specific proteins within cellular environments. Its applications include advancing research on protein regulation and the development of innovative therapeutic strategies. -
PROTAC Linker
Diglycolic acid serves as a versatile PROTAC linker, facilitating the synthesis of proteolysis-targeting chimeras (PROTACs). This compound plays a crucial role in connecting target proteins to E3 ligases, enabling selective degradation pathways. Its application in drug discovery and development highlights its potential in studying protein regulation and therapeutic interventions. -
PROTAC Linker
Methyl 3-(methylamino)propanoate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates the conjugation of target proteins to E3 ligases, promoting selective protein degradation in cellular systems. This compound is essential for researchers focused on targeted protein modulation and therapeutic development in the field of cellular biology. -
PROTAC Linker
Tert-butyl methyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)carbamate is a PROTAC linker designed for the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the selective degradation of target proteins by connecting ligands to E3 ligases, enabling targeted protein modulation. Its application is crucial in studies aimed at the development of novel therapeutic strategies in cancer and other diseases through protein degradation technology. -
PROTAC Linker
tert-Butyl 3-(2-iodoethyl)azetidine-1-carboxylate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in achieving targeted protein degradation, allowing researchers to manipulate cellular pathways through selective protein modulation. Its application is essential in drug discovery and therapeutic development, particularly in the context of oncology and other diseases where protein deregulation occurs. -
PROTAC Linker
Methyl 4-(hydroxymethyl)bicyclo[2.2.2]octane-1-carboxylate serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in the synthesis of PROTACs by linking target proteins to E3 ligases for targeted degradation. Its precise structural properties make it suitable for various applications in chemical biology and drug discovery, particularly in the study and modulation of protein expression levels. -
PROTAC Linker
N1,N6-Dimethylhexane-1,6-diamine serves as a versatile PROTAC linker, facilitating the effective synthesis of PROTAC molecules. Its structural properties enhance the stability and bioavailability of the resulting conjugates, making it crucial for targeted protein degradation studies. This compound plays a significant role in advancing research applications in cancer therapy and other diseases by enabling the selective modulation of protein levels within cells. -
PROTAC Linker
2-(4-Aminocyclohexyl)acetic acid functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by linking an E3 ubiquitin ligase to the protein of interest, thereby promoting targeted protein regulation. It is a valuable tool in chemical biology for studying protein function and therapeutic applications. -
PROTAC Linker
6-Boc-(6-Azaspiro[3.4]octane)-2-amino is a specialized linker utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound facilitates the development of bifunctional molecules that can simultaneously bind to a target protein and an E3 ligase, leading to targeted degradation of substrates. Its structural attributes make it an important tool for researchers investigating targeted protein degradation and drug discovery applications. -
PROTAC Linker
9-Aminononan-1-ol is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). Its primary mechanism involves facilitating the selective degradation of specific target proteins through the recruitment of E3 ligases. This compound serves as an essential building block in the development of novel therapeutics aimed at modulating protein function, enhancing research in the fields of cancer and other diseases reliant on targeted protein degradation. -
PROTAC Linker
tert-Butyl 4-(3-bromopropyl)piperidine-1-carboxylate functions as a PROTAC linker, facilitating the design and synthesis of proteolysis-targeting chimeras (PROTACs). This compound is crucial for creating bifunctional molecules that promote selectivity in targeted protein degradation. Its unique structure allows researchers to effectively connect ligand components, enhancing the efficacy of PROTAC-mediated degradation pathways in various biological studies. -
PROTAC Linker
1,6-Hexanedithiol serves as a versatile linker in the synthesis of PROTACs (proteolysis targeting chimeras). It facilitates the connection between target proteins and E3 ligases, enabling targeted protein degradation. This compound is integral for research focused on protein modulation and therapeutic applications in cancer and other diseases. -
PROTAC Linker
Methyl 3-aminobicyclo[1.1.1]pentane-1-carboxylate serves as a versatile PROTAC linker, facilitating the development of bifunctional small molecules designed for targeted protein degradation. This compound enables effective conjugation between target proteins and ligands, promoting ubiquitination and cellular degradation pathways. Its application is crucial in research focused on protein homeostasis, cellular regulation, and therapeutic discovery in diseases associated with protein misfolding and dysfunction. -
PROTAC Linker
4-Methoxycarbonylcubanecarboxylic acid is a versatile PROTAC linker that plays a crucial role in the synthesis of PROTACs. This compound enhances the targeting and degradation of specific proteins within cells, facilitating studies on protein modulation and degradation pathways. Its unique structural properties make it a valuable tool for researchers investigating targeted protein degradation and therapeutic development. -
PROTAC Linker
Tert-butyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate serves as a PROTAC linker, playing a crucial role in the design and synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound enhances the specificity and efficacy of PROTACs by facilitating the conjugation of target proteins to E3 ligases for targeted degradation. Its unique structural properties make it valuable in research focused on protein regulation and therapeutic development. -
PROTAC Linker
Cbz-PEG2-C2-NH2 is a PROTAC linker designed to facilitate the synthesis of proteolysis-targeting chimeras (PROTACs). Its polyethylene glycol (PEG) structure enhances solubility and biocompatibility, making it suitable for applications in targeted protein degradation studies. Researchers utilize this linker to create more effective PROTACs that can selectively induce the ubiquitination and degradation of specific proteins, thereby advancing drug discovery and therapeutic development. -
PROTAC Linker
tert-Butyl (trans-4-hydroxymethylcyclohexylmethyl)carbamate is a novel PROTAC linker designed to facilitate the synthesis of Proteolysis Targeting Chimeras (PROTACs). It serves as a critical component in the development of bifunctional molecules, promoting targeted degradation of specific proteins within cells. This reagent is essential for researchers focused on protein modulation and therapeutic interventions in various diseases. -
PROTAC Linker
Benzyl (3-aminopropyl)carbamate hydrochloride serves as a PROTAC linker, facilitating the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound is critical in the development of innovative therapeutic strategies by promoting the selective degradation of target proteins. Its application extends to various studies in targeted protein degradation and cellular signaling pathways, making it a valuable tool in chemical biology research. -
PROTAC Linker
Methyl 4-(piperidin-4-ylmethyl)benzoate hydrochloride is a versatile PROTAC linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of targeted protein degradation strategies by facilitating the effective assembly of the targeting and degradation components. Its application is crucial in various research areas, including drug discovery and development, particularly for the modulation of specific protein levels within cellular environments. -
PROTAC Linker
tert-Butyl 7-iodoheptanoate is a versatile PROTAC linker designed for use in the synthesis of proteolysis-targeting chimeras (PROTACs). This compound facilitates the conjugation of target proteins to ubiquitin ligases, enabling targeted protein degradation. Its unique structure enhances the overall stability and efficacy of PROTACs in various biological systems, making it an essential tool for researchers investigating protein homeostasis and therapeutic interventions. -
PROTAC Linker
Methyl 7-bromoheptanoate is a PROTAC linker that facilitates the development of proteolysis-targeting chimeras (PROTACs) for targeted protein degradation. Its structural properties enable efficient conjugation to various ligands and proteins, enhancing the selectivity and efficacy in modulating protein levels within cells. This compound is essential for researchers focused on therapeutic strategies involving the regulation of protein function through targeted degradation. -
PROTAC Linker
((2-Iodoethoxy)methyl)benzene is a PROTAC linker designed for the synthesis of proteolysis targeting chimeras (PROTACs). This compound enables the selective degradation of target proteins by facilitating the formation of a ternary complex with an E3 ligase. Its application in the development of PROTACs provides a powerful strategy for targeted protein modulation in various biological research contexts. -
PROTAC Linker
Mal-amido-PEG9-acid is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the construction of bifunctional molecules that can induce targeted protein degradation, thereby providing a novel approach for modulating protein levels in research applications. Its unique structure enhances solubility and biocompatibility, making it a valuable tool for drug discovery and development in various biological studies. -
PROTAC Linker
Methyl 9-bromononanoate is a versatile PROTAC linker used in the synthesis of proteolysis-targeting chimeras (PROTACs). It facilitates the construction of bifunctional molecules that promote the degradation of target proteins through the ubiquitin-proteasome system. This reagent is crucial for research applications aimed at elucidating protein function and therapeutic intervention in disease models. -
PROTAC Linker
Pent-4-ynal is a versatile PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). By enabling the conjugation of target proteins to E3 ligases, it enhances the selective degradation of specific proteins within cellular pathways. This compound is valuable for research applications focused on targeted protein degradation and the exploration of therapeutic options in oncology and other diseases. -
PROTAC Linker
2-(3-((Tert-butoxycarbonyl)amino)cyclobutyl)acetic acid serves as a versatile PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound enhances the efficacy of protein degradation by linking target proteins with E3 ligases, enabling selective modulation of protein levels. It is valuable for research applications focusing on targeted protein degradation and therapeutic development. -
PROTAC Linker
N-Boc-N-methyl-3-chloro-1-propanamine is a PROTAC linker designed for the synthesis of PROTAC compounds. This reagent enables the construction of bifunctional molecules that can facilitate targeted protein degradation. It is instrumental in research applications focusing on the modulation of protein levels and the exploration of new therapeutic strategies in various disease models. -
PROTAC Linkers
β-Estradiol-6-one 6-(O-carboxymethyloxime) is a PROTAC linker designed for targeted protein degradation. This compound facilitates the development of PROTACs by providing a suitable moiety for conjugation with E3 ligases and target proteins. Its unique structure enables efficient cellular uptake and promotes the degradation of specific proteins, making it valuable for research in biopharmaceuticals and therapeutic applications. -
PROTAC Linker
tert-Butyl (10-bromodecyl)carbamate functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is crucial for creating bifunctional molecules that can selectively induce the degradation of specific proteins, enhancing the study of protein function and regulation. Its robust chemical properties make it an essential tool in targeted protein degradation research and related applications. -
PROTAC Linker
3-(Piperazin-1-yl)propan-1-ol serves as a key linker in PROTAC (Proteolysis Targeting Chimeras) synthesis. Its structure permits effective conjugation of ligand components necessary for targeted protein degradation. This compound is essential in research applications focused on the development and optimization of PROTAC-based therapeutic agents. -
PROTAC Linker
12-(Benzyloxy)-12-oxododecanoic acid serves as an effective PROTAC linker, facilitating the construction of proteolysis-targeting chimeras (PROTACs). This compound plays a critical role in the design of targeted protein degradation systems, enabling selective regulation of protein levels in cellular research. Its utility spans various applications in drug discovery and development, particularly in studies aiming to innovate therapeutic strategies through targeted protein modulation. -
PROTAC Linker
6-Bromohexanenitrile is a chemical linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This linker provides a functional handle for conjugating various target ligands, facilitating the selective degradation of specific proteins within cellular contexts. It plays a crucial role in enhancing the efficacy of targeted protein degradation strategies in pharmaceutical research and drug discovery. -
PROTAC Linker
4-(4-Boc-Piperazino)benzylamine functions as a PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound is essential for the construction of bifunctional molecules that degrade specific disease-related proteins via the ubiquitin-proteasome pathway. It plays a crucial role in targeted protein degradation research and in the design of innovative therapeutic strategies. -
PROTAC Linker
Boc-3,3'-biazetidine hemioxalate is a PROTAC linker designed for the synthesis of PROTAC molecules. This compound facilitates the effective recruitment of E3 ligases, enhancing targeted protein degradation. Its application in drug discovery research allows for the development of innovative therapeutic strategies aimed at modulating protein levels within cells. -
PROTAC Linker
Boc-C17-COOH is a PROTAC (Proteolysis Targeting Chimeras) linker that facilitates the synthesis of PROTACs, enabling targeted protein degradation. Its chemical structure supports the effective conjugation of target proteins and E3 ligases, making it a valuable tool for research in protein homeostasis and regulation. This linker plays a crucial role in advancing studies on targeted therapeutics and the development of innovative treatments for various diseases. -
PROTAC Linker
Methyl 8-bromooctanoate serves as a PROTAC linker, facilitating the development of Proteolysis Targeting Chimeras (PROTACs) that can selectively degrade target proteins. This compound plays a crucial role in expanding the toolbox for targeted protein degradation research and therapeutic applications. Its unique structure enhances the potency and specificity of PROTACs in various biological assays.
